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GOODPASTURES SYNDROME [1 record]

Record 1 2006-05-05

English

Subject field(s)
  • Immunology
DEF

Glomerulonephritis, usually of a generalized proliferative crescent-forming histologic type with a rapidly progressive course, marked by circulating anti-GBM antibodies and linear deposits of immunoglobulin and complement along the glomerular basement membrane. When associated with pulmonary hemorrhage, the condition is called Goodpasture's syndrome.

OBS

In the Merck Manual, these two diseases are synonymous.

French

Domaine(s)
  • Immunologie
CONT

Glomérulonéphrites auto-immunes. La plupart des glomérulonéphrites ont une origine immunitaire. Si le dépôt ou la formation locale de complexes immuns représente le mécanisme le plus fréquemment en cause, l'action néphrotoxique d'autoanticorps dirigés contre la membrane basale glomérulaire (GBM) a été bien démontrée chez certains malades.

Spanish

Campo(s) temático(s)
  • Inmunología
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