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GRAFT HYBRID [1 record]

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Record 1 1997-12-04

English

Subject field(s)
  • Immunology
  • Surgery
CONT

At the NIH, Ildstad and her mentor, David Sachs, tried to induce the same kind of "chimeric" organ tolerance in adult mice. They used a mixture of marrow from the donor and the recipient. To prevent graft vs. host, they filtered mature T cells out. Their hope was that immature immune cells in the mixed bone marrow would grow inside the mouse into a functioning immune system. If all went well, the hybrid immune system would tolerate both donor and recipient cells as "self. "

French

Domaine(s)
  • Immunologie
  • Chirurgie
CONT

Ces cellules se dispersent dans l'organisme et s'y multiplient, créant ainsi un système immunitaire hybride, provenant partiellement de l'animal et partiellement du receveur.

Spanish

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