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HAEMAGGLUTININ [3 records]

Record 1 2018-03-09

English

Subject field(s)
  • Immunology
CONT

Where reverse genetics is used to generate the reassortant vaccine virus, the influenza haemagglutinin and neuraminidase genes may be derived from a variety of sources(egg isolate, mammalian cell isolate, virus in clinical specimen).

CONT

Very few A(H3N2) viruses have been isolated during the 1986-1987 season; however, several appear similar to the A/Stockholm/8/85 variant. The 1986-1987 variant, A/Leningrad/360/86, an egg isolate suitable for vaccine production, appears closely related to A/Stockholm/8/85.

French

Domaine(s)
  • Immunologie
CONT

[Méthode] virologique : isolement viral sur œufs embryonnés avec identification virale par HA [hémagglutination] et IHA [inhibition de l'hémagglutination] (différencier avec autres Paramyxovirus aviaires et virus Influenza) (délai de réponse en cas de résultats négatifs : 6 jours).

Spanish

Save record 1

Record 2 2010-04-20

English

Subject field(s)
  • Immunology
DEF

SB-3(InfanrixTM-DTPa1) is one of a new generation of vaccines for immunisation against pertussis(whooping cough), diphtheria and tetanus. It is a 3-component(pertussis toxin, filamentous haemagglutinin and pertactin) chemically inactivated acellular pertussis-diphtheria-tetanus toxoid(DTaP) vaccine, and it differs from conventional whole-cell pertussis-diphtheria-tetanus toxoid(DTwP) vaccines in that it comprises inactivated purified Bordetella pertussis antigens rather than whole cells of the bacillus.

French

Domaine(s)
  • Immunologie
CONT

L'ELISA et l'immuno-empreinte. Ces techniques permettent de doser séparément des anticorps sériques spécifiques des Bordetelles dirigés contre différents antigènes : toxines telles que la toxine pertussique (PTX) ou l'adényl cyclase-hémolysine (AC-Hly), adhésines telles que l'hémagglutinine filamenteuse (FHA), la pertactine (PRN) et certains agglutinogènes(AGG).

Spanish

Save record 2

Record 3 1987-03-25

English

Subject field(s)
  • Genetics
CONT

A baculovirus transfer vector was constructed using a cloned copy of the autography californica nuclear polyhedrosis virus(AcNPV) polyhedrin gene. The ATG translation initiation codon and 32 bases of the polyhedrin mRNA 5’ leader sequences were deleted and replaced with a cDNA clone of the A/PR/8/34 influenza virus haemagglutinin(HA) gene. The hybrid HA/polyhedrin gene was transferred to AcNPV and polyhedrin-negative recombinants identified which expressed HA activity.

OBS

Extracted from the Pascal data base.

French

Domaine(s)
  • Génétique
OBS

La polyédrine, protéine d'un virus, n'est pas exprimé dans le recombinant génétique

OBS

Proposition d'un biologiste au ministère de la Santé et du Bien-Etre, Canada.

Spanish

Save record 3

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