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HARMONIC IMAGING [2 records]

Record 1 2015-02-12

English

Subject field(s)
  • Nervous System
CONT

In the last decades, imaging membrane potential has become a fruitful approach to study neural circuits, especially in invertebrate preparations with large, resilient neurons. At the same time, particularly in mammalian preparations, voltage imaging methods suffer from poor signal to noise and secondary side effects, and they fall short of providing single-cell resolution when imaging of the activity of neuronal populations. As an introduction to these techniques, we briefly review different voltage imaging methods(including organic fluorophores, SHG [second harmonic generation] chromophores, genetic indicators, hybrid, nanoparticles, and intrinsic approaches) and illustrate some of their applications to neuronal biophysics and mammalian circuit analysis.

French

Domaine(s)
  • Système nerveux
CONT

Les neurobiologistes ont besoin de moyens plus efficaces et moins invasifs pour observer les circuits cérébraux, où des signaux électriques passent d'un neurone à l'autre. [...] Imagerie de voltage. Dans cette technique, on implante un colorant au sein du neurone afin de déterminer si la cellule est active. Il constitue un capteur, qui émet une fluorescence lorsque le champ électrique à travers la membrane cellulaire change de polarité; cela se produit quand un signal électrique passe.

Spanish

Save record 1

Record 2 2010-12-15

English

Subject field(s)
  • Diagnostic Procedures (Medicine)
  • Magnetic Resonance Imaging
DEF

[A] medical imaging technique that images propagating mechanical waves using MRI [magnetic resonance imaging] [to] non-invasively measure... the stiffness of biological tissues.

CONT

Magnetic Resonance Elastography(MRE) uses MRI [magnetic resonance imaging] combined with harmonic mechanical excitation to the tissue to determine how quickly a wave propagates through the organ.... 3 main steps... : send mechanical waves to the region of interest; use modified MRI imaging techniques to image the propagating mechanical waves throughout the organ(wave image) ;process the wave image into an elastogram(mapping of local elasticity).

French

Domaine(s)
  • Méthodes diagnostiques (Médecine)
  • Imagerie par résonance magnétique
CONT

[...] élastographie par résonance magnétique [...] La technique consiste à utiliser un appareil d’imagerie par résonance magnétique (IRM) afin de mesurer les déplacements induits dans les tissus par un vibreur sollicitant le milieu de manière monochromatique (50 à 1000 Hz). [...] Bien que l’élastographie par résonance magnétique permette de reconstituer des cartes d’élasticité en trois dimensions, elle possède deux inconvénients majeurs : le temps d’acquisition et l’immobilité forcée des sujets [...]

Spanish

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