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HOLOENZYME [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2011-01-11

English

Subject field(s)
  • Biological Sciences
  • Biotechnology
DEF

Non-protein substance essential for one or more related enzyme reactions. They include prosthetic groups and coenzymes.

OBS

An enzyme-cofactor complex is termed a holoenzyme while the enzyme alone(inactive without its cofactor) is the apoenzyme.

French

Domaine(s)
  • Sciences biologiques
  • Biotechnologie
DEF

Molécule non protéique servant de cocatalyseur qui reste attaché à l'enzyme pendant tout le cycle réactionnel. Il constitue avec certaines régions des chaînes polypeptidiques le centre actif proprement dit.

Spanish

Campo(s) temático(s)
  • Ciencias biológicas
  • Biotecnología
Save record 1

Record 2 2003-05-23

English

Subject field(s)
  • Biological Sciences
DEF

The catalytically active compound formed by combination of an apoenzyme and its appropriate coenzyme.

CONT

An adsorbent prepared by immobilizing pyridoxamine phosphate as a ligand on CNBr-activated Sepharose was... used for the purification of glutamate-oxoaloacetate transaminase, which has pyrodixal phosphate as a coenzyme. From the chromatographic pattern, it is clear that the holoenzyme(containing enzyme) is not adsorbed on this adsorbent, but the apoenzyme is adsorbed.

French

Domaine(s)
  • Sciences biologiques
DEF

Enzyme complète constituée d'une partie protéique non dialysable, l'apoenzyme, et d'une partie non protéique, dialysable, la coenzyme.

CONT

Quand on compare les domaines de fixation du coenzyme de l'apoenzyme et de l'holoenzyme, les positions des atomes des domaines catalytiques diffèrent considérablement; si on fait tourner le domaine catalytique autour de la charnière, afin de refermer les deux domaines d'environ dix degrés, la plupart des atomes du domaine catalytique de l'apoenzyme se superposent aux atomes correspondants dans l'holoenzyme.

Spanish

Campo(s) temático(s)
  • Ciencias biológicas
Save record 2

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