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METASTASIS [18 records]

Record 1 2025-05-29

English

Subject field(s)
  • Visual Disorders
  • Radiotherapy
CONT

Choroidal melanoma is an ominous malignant tumor of the eye, with propensity for hematogenous metastasis to the liver, lung, and other sites. The management of choroidal melanoma is primarily with enucleation or forms of radiotherapy, including plaque radiotherapy or proton beam radiotherapy.... Despite excellent control, radiotherapy for choroidal melanoma can lead to visually disabling radiation side effects, particularly in patients with macular involvement. These side effects include cataract, retinopathy, papillopathy, and maculopathy. Radiation maculopathy is one of the most common causes of visual loss following radiotherapy and can lead to irreversible blindness.

French

Domaine(s)
  • Troubles de la vision
  • Radiothérapie
OBS

radique : Provoqué par une radiothérapie.

Spanish

Save record 1

Record 2 2018-03-22

English

Subject field(s)
  • Information Processing (Informatics)
  • Biotechnology
  • Genetics
CONT

In this field, user can search all the useful annotations in [the] database, including biological pathway, associated disease, interactors with cancer metastasis-related genes, transcription factors related with cancer metastasis genes, and genomic locations in our database. These search is particularly useful for collecting a gene list with similar bioinformatics annotations.

Key term(s)
  • bio-informatics annotation

French

Domaine(s)
  • Traitement de l'information (Informatique)
  • Biotechnologie
  • Génétique
CONT

On distingue généralement trois niveaux d'annotations bioinformatiques, permettant respectivement de répondre aux questions : où, quoi, et comment?

Key term(s)
  • annotation bio-informatique

Spanish

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Record 3 2015-07-14

English

Subject field(s)
  • Cancers and Oncology
CONT

Peritoneal mesothelioma is the second most common type of mesothelioma.... Spread(metastasis) to distant sites is not common with peritoneal mesothelioma and it does not usually spread to lymph nodes.

French

Domaine(s)
  • Cancers et oncologie
CONT

Le mésothéliome péritonéal est le deuxième type le plus courant de mésothéliome. [...] La propagation (métastases) à distance n’est pas courante pour le mésothéliome péritonéal et il ne se propage généralement pas aux ganglions lymphatiques.

Spanish

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Record 4 2012-02-03

English

Subject field(s)
  • Bronchi
DEF

A malignant tumor(of the lung), usually developing from a nevus and consisting of black masses of cells with a marked tendency to metastasis.

French

Domaine(s)
  • Bronches
DEF

Mélanome malin prenant naissance dans une grosse bronche sous forme d'un lésion sessile infiltrante, pigmentée ou non.

Spanish

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Record 5 2012-02-01

English

Subject field(s)
  • Cancers and Oncology
DEF

Pertaining to, characterized or produced by metastasis; the speading of cancer.

CONT

Metastatic disease. Common sites of metastases of bronchogenic carcinomas include brain, bone, adrenal, and liver.

French

Domaine(s)
  • Cancers et oncologie
DEF

Relatif à une métastase, de la nature d'une métastase (cancer qui se développe par dissémination à distance à partir du foyer primitif).

CONT

Lésions d'origine métastatique.

Spanish

Campo(s) temático(s)
  • Tipos de cáncer y oncología
Save record 5

Record 6 2010-04-29

English

Subject field(s)
  • Genetics
CONT

Colorectal carcinoma is an epithelial neoplastic transformation that results from the accumulation of distinct genetic alterations. There are K-RAS oncogenes on chromosome 12q and there are deletions of the tumor suppressive genes FAP, p53, and DCC on chromosomes 5, 17, and 18, respectively. The deletion of the short arm of chromosome 17 or the long arm of chromosome 18 and activation of the p53, and the deleted colorectal carcinoma(DCC) gene on chromosomes 17 and 18q, respectively, may result in the genetic alterations associated with metastasis.

French

Domaine(s)
  • Génétique
CONT

Des chercheurs américains se sont intéressés au gène DCC (deleted cancer colorectal) et à son expression dans les cellules tumorales. Ce gène est en effet proche d'une région connue du chromosome 18q qui, lorsqu'elle est absente (ou délétée) sur un des chromosomes homologues, est associée à une évolution défavorable du cancer.

Spanish

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Record 7 2010-02-08

English

Subject field(s)
  • Radiography (Medicine)
  • Musculoskeletal System
CONT

Geographic bone destruction. The geographic pattern is the least aggressive pattern of bone destruction, as it is generally indicative of a slow-growing lesion. The margin of the lesion is well defined and easily separated from the surrounding normal bone. This margin may be smooth or irregular, but in either instance, it is usually clearly demarcated, with a short zone of transition from normal to abnormal bone. Benign bone tumors usually demonstrate geographic bone destruction. Malignant diseases(such as plasma cell myeloma and metastasis) and osteomyelitis(particularly granulomatous infections) can demonstrate a similar pattern of bone destruction, however.

French

Domaine(s)
  • Radiographie (Médecine)
  • Appareil locomoteur (Médecine)
CONT

L'ostéolyse géographique se traduit par une lacune à bords nets, à l'emporte-pièce, parfois polycyclique. La séparation entre os sain et os tumoral est nette. Le cortex peut être soit détruit, soit érodé et aminci, mais conservé; il peut être plus ou moins soufflé. Une ostéolyse de type géographique correspond à un processus d'évolution lente. [D'après EMSQU, 31520, A10, s.d., p. 2.]

Spanish

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Record 8 2008-01-09

English

Subject field(s)
  • Cancers and Oncology
CONT

Sweat gland adenocarcinoma is a rare malignancy with high metastatic potential seen more commonly in later years of life. Scalp is the most common site of occurrence and it usually spreads to lymph nodes. Liver, lung and bones are the distant sites of metastasis with fatal results. The differentiation between apocrine and eccrine metastatic sweat gland carcinoma is often difficult.

French

Domaine(s)
  • Cancers et oncologie

Spanish

Save record 8

Record 9 2008-01-03

English

Subject field(s)
  • Cancers and Oncology
DEF

The spread of cancer from its original site to another part of the body.

OBS

The spread of cancer happens because cancer cells break off the original tumor and spread via the blood or lymphatic system.

OBS

The plural form of metastasis is metastases.

Key term(s)
  • metastases

French

Domaine(s)
  • Cancers et oncologie
DEF

Prolifération de [cellules] néoplasiques dans un tissu ou un organe situé à distance d'une tumeur primitive et issue d'elle.

Spanish

Campo(s) temático(s)
  • Tipos de cáncer y oncología
DEF

Propagación de un foco canceroso en un órgano distinto de aquel en que se inició.

Save record 9

Record 10 2005-02-18

English

Subject field(s)
  • Cancers and Oncology
CONT

The osseous metastasis exists in 56 per cent of the cases at the time the primitive neoplasy was discovered, and their presence burdens the final prognostic.

French

Domaine(s)
  • Cancers et oncologie

Spanish

Save record 10

Record 11 2005-02-18

English

Subject field(s)
  • Cancers and Oncology
  • Vertebrae and Bone Marrow
CONT

When reading this study it seems that, in front of vertebral metastasis from thyroidal origin, we should choose the most radical therapeutic attitude as much as possible.

French

Domaine(s)
  • Cancers et oncologie
  • Vertèbres et moelle
CONT

Le nombre de jours d'installation des signes neurologiques était en moyenne de 12 jours (2 à 30 jours) mais n'a pu être précisé que dans 8 cas sur 13. Le délai moyen entre le diagnostic du cancer primitif et l'apparition de la métastase vertébrale était de 69 mois (0 mois - 18 ans).

CONT

Tumeurs primitives responsables des métastases vertébrales et localisations rachidiennes des hémopathies malignes.

Spanish

Save record 11

Record 12 2004-12-03

English

Subject field(s)
  • Cancers and Oncology
DEF

A malignant tumor growing at a secondary site derived from cells which spreads from the original neoplasm.

OBS

The plural form of metastasis is metastases.

French

Domaine(s)
  • Cancers et oncologie
DEF

Tumeur secondaire due à la dissémination de cellules cancéreuses dans divers tissus.

CONT

La propriété la plus importante d'une tumeur maligne est sa capacité, d'une part, à envahir les tissus proches; d'autre part, à se disséminer dans les organes éloignés; cette dissémination à distance, par la circulation sanguine ou lymphatique, est appelée «métastase». La nouvelle tumeur qui en résulte, appelée également «métastase», se met à évoluer pour son propre compte.

Spanish

Campo(s) temático(s)
  • Tipos de cáncer y oncología
DEF

Nuevo foco de una enfermedad debido a la transferencia de su agente causante [...] a otra parte del organismo, desarrollando una lesión similar a la original en el nuevo lugar.

OBS

La metástasis puede ser por contigüidad, por vía linfática o por vía hematógena.

Save record 12

Record 13 2003-01-16

English

Subject field(s)
  • Mineralogy
OBS

... of, relating to, or caused by metastasis...

French

Domaine(s)
  • Minéralogie
OBS

Se dit d'un cristal dont la forme est celle du solide primitif.

Spanish

Campo(s) temático(s)
  • Mineralogía
Save record 13

Record 14 2002-04-26

English

Subject field(s)
  • Histology
  • Biotechnology
CONT

The overall aim of [the Proteases and Tissue Remodeling Unit] is to understand the function of matrix degrading proteolytic enzymes in physiological and pathological tissue remodeling processes, including cancer invasion and metastasis. An area of emphasis is the study of the biochemistry, biology, and pathology of the plasminogen activation system. Ongoing studies include the identification of the target substrates for plasmin during selected physiological and pathological tissue remodeling events...

French

Domaine(s)
  • Histologie
  • Biotechnologie
CONT

[...] cette structure tridimensionnelle (une éponge ou un treillis de polymères, par exemple) sera colonisée après greffe par les cellules de l'hôte, et son architecture servira de guide au remodelage du tissu, pour que ce processus de cicatrisation conduise à un tissu fonctionnel plutôt qu'à un tissu fibreux non fonctionnel.

Spanish

Save record 14

Record 15 1999-06-16

English

Subject field(s)
  • Biochemistry
CONT

Oncogene abnormalities and the microenvironment of the cells, including the extracellular matrix and hormonal milieu, are now understood to be critical determinants of tumorigenesis and metastasis. The molecules we are targeting that participate in tumorigenesis include estrogen, the HER-2/neu tyrosine kinase, and the extracellular matrix protein fibulin-1, thought to function during embryogenesis in the conversion of epithelial cells to migratory mesenchymal cells.

French

Domaine(s)
  • Biochimie
CONT

Les fibulines du latin fibul «étreinte, boucle» sont des protéines de la matrice extracellulaire que l'on retrouve aussi en très faibles concentrations dans le plasma. Elles comprennent trois protéines différentes.

Spanish

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Record 16 1998-12-02

English

Subject field(s)
  • Genetics
CONT

We are examining the effects of MUC1 deficiency on the development and progression of the tumors, as well as studying the effects on metastasis and immunological modulation. A transgenic mouse expressing human MUC1 appropriately as a self molecule has also been developed to provide an appropriate preclinical model for assessing the use of MUC1 protein in immunotherapy.

French

Domaine(s)
  • Génétique
CONT

Les greffes sont rejetées quand l'hôte et le donneur ne partagent pas les mêmes « molécules du soi ».

Spanish

Save record 16

Record 17 1998-07-20

English

Subject field(s)
  • Symptoms (Medicine)
DEF

An enlargement of a single lymph node, usually in the left supraclavicular group. The node is the site of carcinomatous metastasis from a primary lesion in the upper abdomen.

OBS

The term "Virchow’s node" was recommended by the Medical Signs and Symptoms Committee.

French

Domaine(s)
  • Symptômes (Médecine)

Spanish

Save record 17

Record 18 1996-03-21

English

Subject field(s)
  • Vertebrae and Bone Marrow
CONT

Define a specific therapeutic for spinal metastasis from thyroidal origin.

French

Domaine(s)
  • Vertèbres et moelle
CONT

Ces métastases rachidiennes entraînent de par leur localisation des risques d'instabilité mécanique et de complications neurologiques avec en particulier la présence d'épidurite par atteinte le plus souvent de plusieurs vertèbres.

Spanish

Save record 18

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