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MICRONUCLEUS [4 records]

Record 1 2017-12-14

English

Subject field(s)
  • Cytology
  • Biotechnology
DEF

[Related] to or characterized by amitosis.

CONT

Tetrahymena is a single-celled ciliated eukaryote with two nuclei, the macronucleus and the micronucleus. The macronucleus is a large, polyploid nucleus that simply pinches itself off in an amitotic division.

French

Domaine(s)
  • Cytologie
  • Biotechnologie
CONT

L'œsophage, exposé au dommage mécanique causé par l'ingestion de bois haché, est capable de se régénérer rapidement par un processus de division cellulaire simplifié, dit amitotique, qu'on n'a pas l'habitude d'observer dans les tissus des métazoaires où la mitose est de règle.

Spanish

Campo(s) temático(s)
  • Citología
  • Biotecnología
Save record 1

Record 2 2012-01-05

English

Subject field(s)
  • Molecular Biology
DEF

A smaller nucleus located close to and lying partly within a depression on the oral side of the macronucleus.

CONT

A micronucleus(MN) is formed during the metaphase/anaphase transition of mitosis(cell division). It may arise from a whole lagging chromosome(aneugenic event leading to chromosome loss) or an acentric chromosome fragment detaching from a chromosome after breakage(clastogenic event) which do not integrate in the daughter nuclei.

French

Domaine(s)
  • Biologie moléculaire
DEF

Petit noyau, présent en plus du noyau principal des cellules et séparé de celui-ci, produit pendant la télophase de la mitose (méiose) par des chromosomes ou des fragments de chromosomes retardataires.

Spanish

Campo(s) temático(s)
  • Biología molecular
DEF

Núcleo distinto y menor que el núcleo principal de una misma célula.

OBS

Normalmente se forma en telofases anómalas, tanto meióticas como mitóticas, donde los cromosomas individuales o sus fragmentos no alcanzan el polo del huso acromático.

Save record 2

Record 3 2011-08-10

English

Subject field(s)
  • Scientific Research
  • Cytology
  • Pharmacology
CONT

Fluticasone propionate did not induce gene mutation in prokaryotic or eukaryotic cells in vitro. No significant clastogenic effect was seen in cultured human peripheral lymphocytes in vitro or in the mouse micronucleus test when administered at high doses by the oral or subcutaneous routes.

French

Domaine(s)
  • Recherche scientifique
  • Cytologie
  • Pharmacologie

Spanish

Campo(s) temático(s)
  • Investigación científica
  • Citología
  • Farmacología
Save record 3

Record 4 2011-08-09

English

Subject field(s)
  • Genetics
  • Toxicology
CONT

(The micronucleus) test is based on the formation of micronuclei... The procedure is to treat animals with clastogenic agents and, at an appropriate time after treatment,... the total number of polychromatic and normochromatic erythrocytes with and without micronuclei are recorded....

French

Domaine(s)
  • Génétique
  • Toxicologie
CONT

[...] connu sous le nom de «test du micronoyau», [cet essai] destiné à l'étude des lésions chromosomiques [...] est basé sur une augmentation du nombre des micronoyaux dans les érythrocytes polychromatiques des animaux traités [...]

OBS

test micronucleus; test d'induction du micronoyau : équivalents français tirés de la base de données PASCAL.

Spanish

Campo(s) temático(s)
  • Genética
  • Toxicología
DEF

Ensayo in vivo a corto plazo destinado a descubrir las lesiones cromosómicas o del aparato mitótico inducidas por sustancias químicas.

OBS

Este ensayo de basa en un aumento del número de micronúcleos en los eritrocitos policromáticos de los animales tratados respecto de los animales testigo.

Save record 4

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