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MICRONUCLEUS TEST [2 records]

Record 1 2011-08-10

English

Subject field(s)
  • Scientific Research
  • Cytology
  • Pharmacology
CONT

Fluticasone propionate did not induce gene mutation in prokaryotic or eukaryotic cells in vitro. No significant clastogenic effect was seen in cultured human peripheral lymphocytes in vitro or in the mouse micronucleus test when administered at high doses by the oral or subcutaneous routes.

French

Domaine(s)
  • Recherche scientifique
  • Cytologie
  • Pharmacologie

Spanish

Campo(s) temático(s)
  • Investigación científica
  • Citología
  • Farmacología
Save record 1

Record 2 2011-08-09

English

Subject field(s)
  • Genetics
  • Toxicology
CONT

(The micronucleus) test is based on the formation of micronuclei... The procedure is to treat animals with clastogenic agents and, at an appropriate time after treatment,... the total number of polychromatic and normochromatic erythrocytes with and without micronuclei are recorded....

French

Domaine(s)
  • Génétique
  • Toxicologie
CONT

[...] connu sous le nom de «test du micronoyau», [cet essai] destiné à l'étude des lésions chromosomiques [...] est basé sur une augmentation du nombre des micronoyaux dans les érythrocytes polychromatiques des animaux traités [...]

OBS

test micronucleus; test d'induction du micronoyau : équivalents français tirés de la base de données PASCAL.

Spanish

Campo(s) temático(s)
  • Genética
  • Toxicología
DEF

Ensayo in vivo a corto plazo destinado a descubrir las lesiones cromosómicas o del aparato mitótico inducidas por sustancias químicas.

OBS

Este ensayo de basa en un aumento del número de micronúcleos en los eritrocitos policromáticos de los animales tratados respecto de los animales testigo.

Save record 2

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