TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
MONOGENIC [12 records]
Record 1 - internal organization data 2024-09-23
Record 1, English
Record 1, Subject field(s)
- Hygiene and Health
- Human Diseases - Various
Record 1, Main entry term, English
- early-onset obesity
1, record 1, English, early%2Donset%20obesity
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The most common monogenic cause of early-onset obesity is a heterozygous mutation in the gene encoding for the melanocortin 4 receptor(MC4R), a critical regulator of appetite and energy metabolism... 2, record 1, English, - early%2Donset%20obesity
Record 1, Key term(s)
- early onset obesity
Record 1, French
Record 1, Domaine(s)
- Hygiène et santé
- Maladies humaines diverses
Record 1, Main entry term, French
- obésité à début précoce
1, record 1, French, ob%C3%A9sit%C3%A9%20%C3%A0%20d%C3%A9but%20pr%C3%A9coce
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- obésité d'apparition précoce 2, record 1, French, ob%C3%A9sit%C3%A9%20d%27apparition%20pr%C3%A9coce
correct, feminine noun
- obésité précoce 3, record 1, French, ob%C3%A9sit%C3%A9%20pr%C3%A9coce
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les sujets porteurs de mutations de MC4R [récepteur aux mélanocortine de type 4] ont souvent une obésité à début précoce. 1, record 1, French, - ob%C3%A9sit%C3%A9%20%C3%A0%20d%C3%A9but%20pr%C3%A9coce
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2024-09-23
Record 2, English
Record 2, Subject field(s)
- Hygiene and Health
- Genetics
Record 2, Main entry term, English
- polygenic obesity
1, record 2, English, polygenic%20obesity
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
... rare forms of monogenic obesity distinguish themselves from polygenic obesity, which is the most common clinical situation... In polygenic obesity, each susceptibility gene, taken individually, would only have a slight effect on weight. Furthermore, the cumulative contribution of these genes would become significant only in an obesogenic environment(such as overfeeding, sedentary living, stress, etc.). 2, record 2, English, - polygenic%20obesity
Record 2, French
Record 2, Domaine(s)
- Hygiène et santé
- Génétique
Record 2, Main entry term, French
- obésité polygénique
1, record 2, French, ob%C3%A9sit%C3%A9%20polyg%C3%A9nique
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Comme pour toutes les maladies multifactorielles, la contribution de l'hérédité à l'obésité peut être schématisée : - par mutations rares des gènes à fort impact sur l'obésité [...] - soit par l'interaction de plusieurs variants géniques avec un environnement permissif (obésité polygénique). Chaque gène de susceptibilité pris individuellement a de faibles effets sur le poids, et la contribution cumulative de ces gènes ne devient significative qu'en interaction avec des facteurs environnementaux prédisposant à leur expression phénotypique. 2, record 2, French, - ob%C3%A9sit%C3%A9%20polyg%C3%A9nique
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2024-08-19
Record 3, English
Record 3, Subject field(s)
- Hygiene and Health
- Human Diseases - Various
Record 3, Main entry term, English
- syndromic obesity
1, record 3, English, syndromic%20obesity
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
... "syndromic" obesity, in which obesity occurs as one manifestation of a broader syndrome(including monogenic syndromes; hypothyroidism, Cushing's disease, or other endocrinopathies; and such rare causes of obesity as hypothalamic injury). 1, record 3, English, - syndromic%20obesity
Record 3, French
Record 3, Domaine(s)
- Hygiène et santé
- Maladies humaines diverses
Record 3, Main entry term, French
- obésité syndromique
1, record 3, French, ob%C3%A9sit%C3%A9%20syndromique
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Le terme d'obésité syndromique est appliqué aux syndromes dont l'obésité est l'une des constellations de nombreux symptômes, d'ordre endocrinien, neurosensoriel, comportemental et de développement. 1, record 3, French, - ob%C3%A9sit%C3%A9%20syndromique
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2024-08-19
Record 4, English
Record 4, Subject field(s)
- Human Diseases - Various
Record 4, Main entry term, English
- monogenic non-syndromic obesity
1, record 4, English, monogenic%20non%2Dsyndromic%20obesity
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
- monogenic nonsyndromic obesity 2, record 4, English, monogenic%20nonsyndromic%20obesity
correct
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
Monogenic non-syndromic obesity is described as rare and severe early onset obesity associated with endocrine disorders. It is mainly due to mutations in genes of the leptin/melanocortin pathway... 1, record 4, English, - monogenic%20non%2Dsyndromic%20obesity
Record 4, French
Record 4, Domaine(s)
- Maladies humaines diverses
Record 4, Main entry term, French
- obésité monogénique non syndromique
1, record 4, French, ob%C3%A9sit%C3%A9%20monog%C3%A9nique%20non%20syndromique
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Obésités monogéniques non syndromiques. L'impact de la génétique est ici majeur et très peu dépendant des facteurs environnementaux. Ces obésités sont principalement causées par des mutations dans les gènes de la voie leptine-mélanocortines qui joue un rôle clé dans le contrôle de la prise alimentaire [...] 1, record 4, French, - ob%C3%A9sit%C3%A9%20monog%C3%A9nique%20non%20syndromique
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2024-08-19
Record 5, English
Record 5, Subject field(s)
- Hygiene and Health
- Genetics
Record 5, Main entry term, English
- genetic obesity
1, record 5, English, genetic%20obesity
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
Genetic obesity is categorized into several types based on the way genes are involved... Monogenic obesity : Excessive weight caused by a mutation in a single gene.... Polygenic obesity : Variations in multiple genes contribute to the susceptibility to obesity in small ways.... Syndromic obesity : Genetic changes in specific diseases, like Prader-Willi syndrome, can directly lead to obesity. 2, record 5, English, - genetic%20obesity
Record 5, French
Record 5, Domaine(s)
- Hygiène et santé
- Génétique
Record 5, Main entry term, French
- obésité génétique
1, record 5, French, ob%C3%A9sit%C3%A9%20g%C3%A9n%C3%A9tique
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2024-08-19
Record 6, English
Record 6, Subject field(s)
- Hygiene and Health
- Genetics
Record 6, Main entry term, English
- monogenic obesity
1, record 6, English, monogenic%20obesity
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
Monogenic obesity is defined as obesity resulting from a mutation or deficiency of a single gene. 2, record 6, English, - monogenic%20obesity
Record 6, French
Record 6, Domaine(s)
- Hygiène et santé
- Génétique
Record 6, Main entry term, French
- obésité monogénique
1, record 6, French, ob%C3%A9sit%C3%A9%20monog%C3%A9nique
correct, feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
L'obésité monogénique, une forme rare d’obésité qui affecte un seul gène. Plusieurs formes rares d'obésité [...] résultent de mutations sur des gènes uniques, ou mutations monogéniques, notamment sur ceux qui jouent un rôle dans le contrôle de l'appétit. La sensation de faim est donc très importante, voire irrépressible, entrainant de facto une prise de poids qui mène à l'obésité. 2, record 6, French, - ob%C3%A9sit%C3%A9%20monog%C3%A9nique
Record 6, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2011-09-07
Record 7, English
Record 7, Subject field(s)
- Mathematics
Record 7, Main entry term, English
- Riemann surface
1, record 7, English, Riemann%20surface
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 DEF
The relation between complex numbers "z" and complex numbers "w" expressed by the monogenic analytic function "w=f(z) "might be one-to-one, one-to-many, many-to-one, or many-to-many. 2, record 7, English, - Riemann%20surface
Record 7, French
Record 7, Domaine(s)
- Mathématiques
Record 7, Main entry term, French
- surface de Riemann
1, record 7, French, surface%20de%20Riemann
correct, feminine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 OBS
En 1857, le mathématicien allemand Bernhardt Riemann fonda la théorie des fonctions algébriques où apparaît la conception des «surfaces de Riemann». 2, record 7, French, - surface%20de%20Riemann
Record 7, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 2003-09-09
Record 8, English
Record 8, Subject field(s)
- Genetics
Record 8, Main entry term, English
- apospory
1, record 8, English, apospory
correct
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record number: 8, Textual support number: 1 CONT
The most important tropical forages are Brachiaria spp. Existing cultivars are natural, polyploid, aposporous apomicts. Breeding programs seek to combine attributes from the tetraploid apomicts B. brizantha and B. decumbens. Apomixis is monogenic and dominant. We sought to synthesize an allogomous, sexual, breeding population containing germplasm from selected apomicts. Apospory was not detected in a large open-pollinated progeny of sexual hybrids from sexual-by-apomictic crosses. 2, record 8, English, - apospory
Record 8, French
Record 8, Domaine(s)
- Génétique
Record 8, Main entry term, French
- aposporie
1, record 8, French, aposporie
correct, feminine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 DEF
Reproduction des végétaux par développement du gamétophyte à partir d'une cellule végétative diploïde du sporophyte (et non pas d'une spore haploïde). 1, record 8, French, - aposporie
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Genética
Record 8, Main entry term, Spanish
- aposporia
1, record 8, Spanish, aposporia
correct, feminine noun
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
Record 8, Textual support, Spanish
Record number: 8, Textual support number: 1 DEF
Apomixia o reproducción sin fecundación basada en la producción de un gametofito a partir de un grupo de células del esporofito. 1, record 8, Spanish, - aposporia
Record 9 - internal organization data 2003-06-02
Record 9, English
Record 9, Subject field(s)
- Genetics
Record 9, Main entry term, English
- monogenic
1, record 9, English, monogenic
correct, adjective
Record 9, Abbreviations, English
Record 9, Synonyms, English
Record 9, Textual support, English
Record number: 9, Textual support number: 1 CONT
monogenic diseases : genetic diseases associated with a single gene(e. g. sickle cell anemia). 2, record 9, English, - monogenic
Record 9, French
Record 9, Domaine(s)
- Génétique
Record 9, Main entry term, French
- monogénique
1, record 9, French, monog%C3%A9nique
correct, adjective
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 CONT
Les progrès réalisés dans ce domaine ont déjà permis d'isoler des gènes associés à des maladies tant monogéniques que multifactorielles (cancers familiaux du sein et du côlon, obésité, maladie de Hungtington, syndrome de Menkes, ataxie-télangiactasie, etc.). 2, record 9, French, - monog%C3%A9nique
Record 9, Spanish
Record 9, Campo(s) temático(s)
- Genética
Record 9, Main entry term, Spanish
- monogénico
1, record 9, Spanish, monog%C3%A9nico
correct, adjective
Record 9, Abbreviations, Spanish
Record 9, Synonyms, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 1999-05-19
Record 10, English
Record 10, Subject field(s)
- Mathematics
Record 10, Main entry term, English
- lacunary space
1, record 10, English, lacunary%20space
correct
Record 10, Abbreviations, English
Record 10, Synonyms, English
Record 10, Textual support, English
Record number: 10, Textual support number: 1 DEF
A space in the z-plane no point of which is covered by the domain of existence of a given monogenic analytic function. 2, record 10, English, - lacunary%20space
Record 10, French
Record 10, Domaine(s)
- Mathématiques
Record 10, Main entry term, French
- espace lacunaire
1, record 10, French, espace%20lacunaire
correct, masculine noun
Record 10, Abbreviations, French
Record 10, Synonyms, French
Record 10, Textual support, French
Record 10, Spanish
Record 10, Textual support, Spanish
Record 11 - internal organization data 1998-09-03
Record 11, English
Record 11, Subject field(s)
- Petrography
- Geology
Record 11, Main entry term, English
- monogenic breccia
1, record 11, English, monogenic%20breccia
correct
Record 11, Abbreviations, English
Record 11, Synonyms, English
- monomict breccia 2, record 11, English, monomict%20breccia
correct
Record 11, Textual support, English
Record number: 11, Textual support number: 1 DEF
Breccia in which all the fragments have essentially the same composition ... 2, record 11, English, - monogenic%20breccia
Record number: 11, Textual support number: 1 CONT
Breccias by impregnation and disruption... appear as monogenic breccias formed by angular fragments of similar composition bound by a homogeneous nonclastic cement... 3, record 11, English, - monogenic%20breccia
Record 11, Key term(s)
- monogenetic breccia
Record 11, French
Record 11, Domaine(s)
- Pétrographie
- Géologie
Record 11, Main entry term, French
- brèche monogénique
1, record 11, French, br%C3%A8che%20monog%C3%A9nique
correct, feminine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
Record 11, Textual support, French
Record 11, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 1997-03-20
Record 12, English
Record 12, Subject field(s)
- Genetics
Record 12, Main entry term, English
- monogenic hereditary disease
1, record 12, English, monogenic%20hereditary%20disease
correct
Record 12, Abbreviations, English
Record 12, Synonyms, English
Record 12, Textual support, English
Record number: 12, Textual support number: 1 CONT
The foundation for our current studies has been a detailed investigation of the molecular genetics of retinoblastoma, a paradigm for familial cancer predisposition and a classic monogenic hereditary disease. 1, record 12, English, - monogenic%20hereditary%20disease
Record number: 12, Textual support number: 1 OBS
monogenic character : a character determined by a single gene. 2, record 12, English, - monogenic%20hereditary%20disease
Record 12, French
Record 12, Domaine(s)
- Génétique
Record 12, Main entry term, French
- maladie héréditaire monogénique
1, record 12, French, maladie%20h%C3%A9r%C3%A9ditaire%20monog%C3%A9nique
correct, feminine noun
Record 12, Abbreviations, French
Record 12, Synonyms, French
Record 12, Textual support, French
Record number: 12, Textual support number: 1 CONT
Surtout, on entrevoit de claires indications à la thérapie génique. À côté des maladies héréditaires monogéniques, où l'on compte quelques succès (déficit ADA, mucopolysaccharidoses) et des échecs temporaires (muscovidose), l'intérêt de la thérapie génique s'est vite déplacée vers les maladies acquises polygéniques comme le cancer. 1, record 12, French, - maladie%20h%C3%A9r%C3%A9ditaire%20monog%C3%A9nique
Record number: 12, Textual support number: 1 OBS
Génétique moléculaire. 2, record 12, French, - maladie%20h%C3%A9r%C3%A9ditaire%20monog%C3%A9nique
Record 12, Spanish
Record 12, Textual support, Spanish
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