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The Government of Canada’s terminology and linguistic data bank.

NGF [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2001-11-22

English

Subject field(s)
  • Biochemistry
  • Morphology and General Physiology
CONT

Nerve growth factor(NGF) is the prototype for the neurotrophin family of polypeptides which are essential in the developments and survival of certain sympathetic and sensory neurons in both the central and peripheral nervous systems. NGF was discovered when mouse sarcoma tissue transplants in chicken embryos caused an increase in the size of spinal ganglia.

French

Domaine(s)
  • Biochimie
  • Morphologie et physiologie générale
DEF

Facteur de croissance neurotrophique nécessaire à la survie neuronale et stimulant la croissance des neurites.

OBS

Elle intervient dans la régulation de la mort neuronale programmée au cours du développement embryonnaire et dans la croissance axonale pendant la regénération nerveuse.

OBS

Facteur ayant une application thérapeutique potentielle dans la maladie d'Alzheimer et dans les cas de neuropathologies liés au diabète.

Spanish

Save record 1

Record 2 1991-08-30

English

Subject field(s)
  • Biochemistry
CONT

Retinoic acid promotes the neuronal survival properties of the class 1 heparin-binging growth factor(HBGF-1) on 8-day-old chick ciliary and sensory neurones. It has little or no effect on the survival promoting properties of class 2 heparin-binding growth factor(HBGF-2) on these cell types. Nerve growth factor(NGF) promoted survival of sympathetic and sensory neurones, and was unaffected at any concentration of retinoic acid.

OBS

Tiré de Brain Research, 1991, 552 (1), 29-34.

French

Domaine(s)
  • Biochimie
CONT

Les facteurs angiogéniques sont nombreux; beaucoup d'entre eux ont la propriété de se fixer à l'héparine ou à des glucosaminoglycanes de la matrice extracellulaire. Ils forment ainsi la famille des HBGF (heparin-binding growth factors). HBGS-1 est identique au FGF acide (fibroblast growth factor) alors que HBGF-2 est le FGF basique.

Spanish

Save record 2

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