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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

The traffic through the nuclear envelope is mediated by a protein family which can be divided into exportins and importins. Binding of a molecule(a "cargo") to exportins facilitates its export to the cytoplasm. Importins facilitate import into the nucleus.  2, record 1, English, - importin

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Caryophérine du cytosol qui assure, au niveau d'un pore nucléaire, le transport vers l'intérieur du noyau de protéines pourvues d'une séquence d'importation nucléaire.  2, record 1, French, - importine

Record number: 1, Textual support number: 1 OBS

importine : terme et définition publiés au Journal officiel de la République française le 12 septembre 2019.  3, record 1, French, - importine

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

The traffic through the nuclear envelope is mediated by a protein family which can be divided into exportins and importins. Binding of a molecule(a "cargo") to exportins facilitates its export to the cytoplasm. Importins facilitate import into the nucleus.  2, record 2, English, - exportin

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Caryophérine du noyau cellulaire, qui assure, au niveau d'un pore nucléaire, le passage, dans le cytoplasme, d'ARN [acide ribonucléique], notamment messager, et de protéines pourvues d'une séquence d'exportation nucléaire.  2, record 2, French, - exportine

Record number: 2, Textual support number: 1 OBS

exportine : terme et définition publiés au Journal officiel de la République française le 12 septembre 2019.  3, record 2, French, - exportine

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

An organism(e. g., a bacterium or a blue-green alga), which does not have a true nucleus, the nuclear membrane being absent and the nuclear structures being collected in a nuclear region, or nucleoid, and the chromosomes lying naked(not combined with protein) in the cytoplasm of the cell. They usually have a rigid cell wall; they lack internal cellular structures such as mitochondria. All reproduce by cell division.  3, record 3, English, - prokaryote

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Organisme simple tel que les bactéries ou les algues bleues ne possédant ni membrane nucléaire ni organites limités par une membrane. Le matériel chromosomique baigne directement dans le cytoplasme.  2, record 3, French, - procaryote

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

A 96-amino acid(14 kd) protein, which is incorporated into the virion. It interacts with the p6gag part of the Pr55gag precursor. Vpr detected in the cell is localized to the nucleus. Proposed functions for Vpr include the nuclear import of preintegration complexes, cell growth arrest, transactivation of cellular genes, and induction of cellular differentiation. Found in HIV-1, HIV-2, SIVmac and SIVmnd. It is homologous to VPX of SIVagm.  2, record 4, English, - viral%20protein%20u

Record number: 4, Textual support number: 1 OBS

Glossary in molecular biology (Portions of the glossary text were taken directly or modified from definitions in the U.S. Congress Office of Technology Assessment document).  3, record 4, English, - viral%20protein%20u

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Une des protéines du rétrovirus HIV-1 qui participe avec la protéine Vif à la maturation du virus.  2, record 4, French, - prot%C3%A9ine%20virale%20u

Record 4,  Textual support,  Spanish

Record number: 4, Textual support number: 1 OBS

Uno de los tres genes auxiliares del VIH [virus de la inmunodeficiencia humana].  1, record 4, Spanish, - vpu

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

[After a patient, Smith] an uncharacterized nuclear antigen that is a nonhistone acidic protein not complexed with DNA or RNA; anti-Sm antibodies make up a part of the antinuclear antibodies in about one-third of patients with systemic lupus erythematosus, but do not occur in other connective tissue diseases, except mixed connective tissue disease.  1, record 5, English, - Sm%20antigen

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

Anticorps anti-Sm. Découvert pour la première fois chez un malade dénommé Smith, cet anticorps est très spécifique du LED (20 à 30% des malades). L'antigène Sm est composé de polypeptides présents dans les "small nuclear ribonucleoproteins" (snRNP) contenant des petits ARN riches en uridine (U snRNP) qui participent à l'épissage de l' ARN messager.  1, record 5, French, - antig%C3%A8ne%20Sm

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 CONT

The mature MA protein remains associated with the inner side of the lipid envelope. In addition, MA plays a role in the transport of the preintegration complex to the nucleus. A nuclear localization signal(NLS) has been proposed within the MA protein, located between residues 14-36 and 107-116 of the HIV-1 p17MA protein.  3, record 6, English, - nuclear%20localization%20signal

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

L'une des bases moléculaires du transport nucléaire réside dans l'existence d'une signalétique particulière. De courts signaux peptidiques présents au sein des molécules à transporter sont reconnus par des récepteurs spécifiques et déterminent ainsi la nature de la molécule et sa destination finale au travers de la membrane nucléaire. Le signal de localisation nucléaire NLS (nuclear localization signal) est le mieux caractérisé. Composé d'acides aminés basiques, il permet aux protéines qui le possèdent d'être importées dans le noyau cellulaire.  1, record 6, French, - signal%20de%20localisation%20nucl%C3%A9aire

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

The Food and Drug Administration has approved an enzyme immunoassay for the in vitro quantitative determination of nuclear matrix protein NMP22 in stabilized voided urine, the Matritech NMP22R Test Kit(Matritech Inc.). The test kit is indicated as an aid in the management of patients with transition cell carcinoma of the urinary tract, after surgical treatment to identify those patients with occult or rapidly recurring cancer.  3, record 7, English, - transition%20cell%20carcinoma

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

Parmi les affections malignes du système urinaire, le cancer de la vessie ou carcinome des cellules de transition (TCC) est le plus répandu. Pour les seuls États-Unis, par exemple, il touche 51 000 personnes.  1, record 7, French, - carcinome%20des%20cellules%20de%20transition

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

A very original set of experiments carried out by the Unit of Molecular Biology of Gene Expression concerns another protein essential for mouse development that is also a transcription factor. This factor known as KBF2 or RBP-Jk is homologous to a Drosophila gene product, Su(H)(Suppressor of Hairless), which belongs to the Notch signal transduction cascade involved in regulating the competence of a cell to respond to specific developmental cues. A likely function of the Su(H) protein is to serve as an anchor on DNA for non DNA-binding transcriptional activators. This function is conserved in the Notch pathway : the activation of this transmembrane receptor likely involves a proteolytic cleavage step which releases its intracellular domain; following nuclear translocation, it activates its target genes by binding to the Su(H) protein, which is already bound to several sites in the target promoters.  2, record 8, English, - Su%28H%29%20protein

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

La protéine Su(H), impliquée dans l'activité de transmission de ce signal, semble capable de s'associer à la région intracellulaire de Notch. C'est un facteur de transcription qui se lie à certaines séquences localisées dans les promoteurs de plusieurs des gènes cibles de Notch.  1, record 8, French, - prot%C3%A9ine%20Su%28H%29

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

We report the cDNA deduced primary structure of a wheat germ agglutinin-reactive nuclear pore complex(NPC) protein of rat. The protein, termed Nup98(for nucleoporin of 98 kDa), contains numerous GLFG and FG repeats and some FXFG repeats and is thus a vertebrate member of a family of GLFG nucleoporins that were previously discovered in yeast.  1, record 9, English, - nucleoporin

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 CONT

Les nucléoporines, constituants des pores nucléaires, règlent le trafic nucléo-cytoplasmique de protéines et d'ARN.  1, record 9, French, - nucl%C3%A9oporine

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 DEF

A 96-amino acid(14 kd) protein, which is incorporated into the virion. It interacts with the p6gag part of the Pr55gag precursor. the Vpr detected in the cell is localized to the nucleus. Proposed funtions for Vpr include the nuclear import of preintegration complexes, cell growth arrest, transactivation of cellular genes, and induction of cellular differentiation. Found in HIV-1, HIV-2, SIVmac and SIVmnd, It is homologous to VPX of SIVmgm.  2, record 10, English, - virus%2Dencoded%20protein

Record number: 10, Textual support number: 1 OBS

Glossary of molecular biology (portions of the glossary text were taken directly or modified from definitions in the U.S. Congress Office of Technology Assessment document).  3, record 10, English, - virus%2Dencoded%20protein

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 CONT

Le processus de transcription inverse commence pendant l'encapsidation de l'ARN. Il n'est pas initié par un ARN de transfert, comme chez les rétrovirus, mais par une protéine virale qui n'est autre que la polymérase.  3, record 10, French, - prot%C3%A9ine%20virale

Record number: 10, Textual support number: 1 OBS

Équivalents français approuvés par l'Unité de recherche en vaccinologie, Laboratoire et Service d'infectiologie, Centre hospitalier de l'université Laval (CHUL), Québec.  4, record 10, French, - prot%C3%A9ine%20virale

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

Activin, a member of the transforming growth factor-beta family of peptides, is implicated in the regulation of cell growth and differentiation in a variety of biological systems. We have sought to identify immediate early genes whose altered expression may provide a common nuclear event involved in activin-regulated phenotypic changes in many cell types. In both human K562 myelogenous leukemia and rat PC12 pheochromocytoma cells, activin treatment caused transient transcription-dependent and protein synthesis-independent increases of junB messenger RNA(mRNA) within 1 hour... [Source : PASCAL database].  1, record 11, English, - activin

Record number: 11, Textual support number: 1 OBS

Activin A not only stimulates the synthesis and release of pituitary follicle-stimulating hormones but exerts various effects on haematopoietic cells, embryos, and fibroblasts [Source: PASCAL database].  1, record 11, English, - activin

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 CONT

Les activines, des inducteurs du mésoderme axial chez le xénope et le poulet. Nous avons rapporté [...] que l'inducteur mésodermique XTC-MIF (mesoderm inducing factor dérivé de la lignée de xénope XTC), appartenant à la famille TGF B, était l'équivalent de l'activine chez Xenopus.  1, record 11, French, - activine

Record 11,  Textual support,  Spanish