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SICKLE HEMOGLOBIN [5 records]
Record 1 - internal organization data 2024-07-31
Record 1, English
Record 1, Subject field(s)
- Genetics
- Blood
Record 1, Main entry term, English
- sickle cell hemoglobin
1, record 1, English, sickle%20cell%20hemoglobin
correct
Record 1, Abbreviations, English
- HbS 1, record 1, English, HbS
correct
Record 1, Synonyms, English
- sickle hemoglobin 2, record 1, English, sickle%20hemoglobin
correct
- HbS 2, record 1, English, HbS
correct
- HbS 2, record 1, English, HbS
- hemoglobin S 3, record 1, English, hemoglobin%20S
correct
- HbS 3, record 1, English, HbS
correct
- HbS 3, record 1, English, HbS
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Sickle cell hemoglobin(HbS) is a hemoglobin(Hb) variant characterized by point mutation causing replacement of glutamic acid by valine at position 6 of the β globin chain, which results in sickling phenomenon in low oxygen states, acidosis, and dehydration. 1, record 1, English, - sickle%20cell%20hemoglobin
Record 1, Key term(s)
- sickle-cell hemoglobin
- sickle cell haemoglobin
- sickle-cell haemoglobin
- sickle haemoglobin
- haemoglobin S
Record 1, French
Record 1, Domaine(s)
- Génétique
- Sang
Record 1, Main entry term, French
- hémoglobine drépanocytaire
1, record 1, French, h%C3%A9moglobine%20dr%C3%A9panocytaire
correct, feminine noun
Record 1, Abbreviations, French
- HbS 1, record 1, French, HbS
correct, feminine noun
Record 1, Synonyms, French
- hémoglobine S 2, record 1, French, h%C3%A9moglobine%20S
correct, feminine noun
- HbS 3, record 1, French, HbS
correct, feminine noun
- HbS 3, record 1, French, HbS
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La production d'une hémoglobine mutée appelée hémoglobine S (HbS) est à l'origine de nombreuses complications. Cette HbS a la particularité de polymériser en conditions désoxygénées engendrant la falciformation des globules rouges. 3, record 1, French, - h%C3%A9moglobine%20dr%C3%A9panocytaire
Record number: 1, Textual support number: 1 OBS
hémoglobine S : Dans cette désignation, l'abréviation «S» provient du mot anglais «sickle» qui signifie «faucille». 4, record 1, French, - h%C3%A9moglobine%20dr%C3%A9panocytaire
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2024-07-24
Record 2, English
Record 2, Subject field(s)
- Human Diseases - Various
- Genetics
- Blood
Record 2, Main entry term, English
- sickle cell disease
1, record 2, English, sickle%20cell%20disease
correct
Record 2, Abbreviations, English
- SCD 2, record 2, English, SCD
correct
Record 2, Synonyms, English
- sickle cell disorder 3, record 2, English, sickle%20cell%20disorder
correct
- SCD 4, record 2, English, SCD
correct
- SCD 4, record 2, English, SCD
- sickle-cell disorder 5, record 2, English, sickle%2Dcell%20disorder
correct
- drepanocytosis 6, record 2, English, drepanocytosis
obsolete
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
Any of the diseases associated with the presence of hemoglobin S and sickle cells... 7, record 2, English, - sickle%20cell%20disease
Record number: 2, Textual support number: 1 OBS
[It includes] sickle cell anemia, sickle cell-hemoglobin C disease, sickle cell-hemoglobin D disease, and sickle cell-thalassemia disease. 7, record 2, English, - sickle%20cell%20disease
Record 2, Key term(s)
- sickle-cell disease
Record 2, French
Record 2, Domaine(s)
- Maladies humaines diverses
- Génétique
- Sang
Record 2, Main entry term, French
- maladie falciforme
1, record 2, French, maladie%20falciforme
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- drépanocytose 2, record 2, French, dr%C3%A9panocytose
correct, feminine noun
- maladie drépanocytaire 2, record 2, French, maladie%20dr%C3%A9panocytaire
correct, feminine noun
- affection drépanocytaire 3, record 2, French, affection%20dr%C3%A9panocytaire
correct, feminine noun
- affection à hématies falciformes 4, record 2, French, affection%20%C3%A0%20h%C3%A9maties%20falciformes
feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Les altérations cellulaires sont une constante de la maladie drépanocytaire. En effet, dans sa forme désoxygénée l'HbS [hémoglobine S] polymérise et déforme le globule rouge qui devient fragile et rigide. Ce dernier prend alors la forme d’une faucille d'où le nom de falciformation donné à ce phénomène. 5, record 2, French, - maladie%20falciforme
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2012-03-05
Record 3, English
Record 3, Subject field(s)
- Blood
Record 3, Main entry term, English
- hemoglobinopathy
1, record 3, English, hemoglobinopathy
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
Any inherited disorder caused by abnormalities of hemoglobin, resulting in conditions such as sickle cell anemia, hemolytic anemia, or thalassemia. 1, record 3, English, - hemoglobinopathy
Record 3, French
Record 3, Domaine(s)
- Sang
Record 3, Main entry term, French
- hémoglobinopathie
1, record 3, French, h%C3%A9moglobinopathie
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Groupe de maladies caractérisées par une anomalie de l'hémoglobine. 2, record 3, French, - h%C3%A9moglobinopathie
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2007-08-08
Record 4, English
Record 4, Subject field(s)
- Blood
Record 4, Main entry term, English
- sickle cell
1, record 4, English, sickle%20cell
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
- drepanocyte 2, record 4, English, drepanocyte
correct
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
An erythrocyte shaped like a sickle or crescent, the abnormal shape caused by the presence of varying proportions of hemoglobin S. 1, record 4, English, - sickle%20cell
Record number: 4, Textual support number: 1 OBS
When a person with sickle cell anemia is exposed to dehydration, infection, or low oxygen supply, their fragile red blood cells form liquid crystals and assume a crescent shape causing red cell destruction and thickening of the blood. 1, record 4, English, - sickle%20cell
Record 4, Key term(s)
- crescent cell
Record 4, French
Record 4, Domaine(s)
- Sang
Record 4, Main entry term, French
- drépanocyte
1, record 4, French, dr%C3%A9panocyte
correct, masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
La drépanocytose [...] la polymérisation de l'Hb [l'hémoglobine] en de longues fibres [déforme le globule rouge] en lui donnant l'aspect d'une faucille (drépanocyte). 2, record 4, French, - dr%C3%A9panocyte
Record 4, Key term(s)
- érythrocyte en faucille
- cellule en faucille
- cellule falciforme
- érythrocyte falciforme
- hématie falciforme
- hématie en faucille
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Sangre
Record 4, Main entry term, Spanish
- drepanocito
1, record 4, Spanish, drepanocito
correct, masculine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
- célula falciforme 2, record 4, Spanish, c%C3%A9lula%20falciforme
correct, feminine noun
Record 4, Textual support, Spanish
Record number: 4, Textual support number: 1 DEF
Hematíe maduro en forma de hoz, debido a la presencia de una hemoglobina anormal. 2, record 4, Spanish, - drepanocito
Record 5 - internal organization data 2004-12-03
Record 5, English
Record 5, Subject field(s)
- Blood
Record 5, Main entry term, English
- hemolysis
1, record 5, English, hemolysis
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
Destruction of the red cell membrane causing release of hemoglobin. 2, record 5, English, - hemolysis
Record number: 5, Textual support number: 1 CONT
Hemolysis of sickle cells is both extravascular and intravascular. The former is due to the effects of unstable Hb [hemoglobin] S and recurrent sickling on causing oxidative damage to cell membranes. 3, record 5, English, - hemolysis
Record 5, Key term(s)
- haemolysis
- haemocytolysis
Record 5, French
Record 5, Domaine(s)
- Sang
Record 5, Main entry term, French
- hémolyse
1, record 5, French, h%C3%A9molyse
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 DEF
Destruction des globules rouges provoquant la libération de l'hémoglobine. 2, record 5, French, - h%C3%A9molyse
Record number: 5, Textual support number: 1 CONT
hémolyse intra-vasculaire. 3, record 5, French, - h%C3%A9molyse
Record 5, Key term(s)
- hemocytolyse
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Sangre
Record 5, Main entry term, Spanish
- hemólisis
1, record 5, Spanish, hem%C3%B3lisis
correct, feminine noun
Record 5, Abbreviations, Spanish
Record 5, Synonyms, Spanish
- hemocitólisis 2, record 5, Spanish, hemocit%C3%B3lisis
feminine noun
Record 5, Textual support, Spanish
Record number: 5, Textual support number: 1 DEF
Destrucción de glóbulos rojos. 3, record 5, Spanish, - hem%C3%B3lisis
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