TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Since alleles derived from different parental origins that are identical in nucleotide sequence may exhibit imprinting, the differences between the paternal and maternal genetic material are due to differential programming during spermatogenesis or oogenesis. The different packaging constraints of the sperm cell compared with the ovum also may be important. The regulatory mechanisms superimpose on the nucleotide sequence of a gene to determine the location, timing and degree of expression, and are termed epigenetic effects. Epigenetic modification(rather than genetic divergence of the gametes) of the DNA is likely to be the signal that marks the sperm and egg alleles as different. Imprinting is a special type of epigenetic inheritance that is passed through the gene line into somatic tissues of the progeny and is parent-specific.  1, record 1, English, - epigenetic%20modification

Record number: 1, Textual support number: 1 OBS

epigenetic: The absence of factors in the genotype that exerts an effect upon the phenotype.  2, record 1, English, - epigenetic%20modification

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Altération chromosomique pouvant être héritée et réversible, qui se surimpose à la séquence nucléotidique.  1, record 1, French, - modification%20%C3%A9pig%C3%A9n%C3%A9tique

Record number: 1, Textual support number: 1 OBS

Le niveau supplémentaire d'information ainsi créé permettrait, par exemple, de distinguer l'origine parentale des chromosomes.  1, record 1, French, - modification%20%C3%A9pig%C3%A9n%C3%A9tique

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

In vivo assembly of infectious AAV virion requires the presence of the inverted terminal repeats on the packaged DNA suggesting that the signal for packaging in vivo is located within the TR sequences(Samulski et al. 1989 J. Virol. 63 : 3822-3828; McLaughlin et al. 1988 J. Virol. 62 : 1963-1973).  3, record 2, English, - inverted%20terminal%20repeat

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Le génome de l'AAV est constitué d'une copie d'ADN simple brin de 4,7 kb incluse dans une capside dépourvue d'enveloppe. L'organisation génétique est simple, ne comportant que deux cadres de lecture (rep et cap) et deux répétitions terminales (ITR) d'environ 140 pb.  3, record 2, French, - r%C3%A9p%C3%A9tition%20terminale%20invers%C3%A9e

Record 2,  Textual support,  Spanish