TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

SIGNALING FUNCTION [3 records]

Record 1 2025-04-08

English

Subject field(s)
  • Morphology and General Physiology
  • Molecular Biology
CONT

Transient receptor potential(TRP) channels are transmembrane protein complexes that play important roles in the physiology and pathophysiology of both the central nervous system(CNS) and the peripheral nerve system(PNS). TRP channels function as non-selective cation channels that are activated by several chemical, mechanical, and thermal stimuli as well as by pH [potential of hydrogen], osmolarity, and several endogenous or exogenous ligands, second messengers, and signaling molecules.

French

Domaine(s)
  • Morphologie et physiologie générale
  • Biologie moléculaire
CONT

La sensibilité des canaux TRP à une grande variété de stimuli physiques et chimiques leur permet d'être des acteurs essentiels de différentes fonctions sensorielles telles que la vision, l'audition, le goût, les sensations thermiques et tactiles, l'état d'oxydoréduction, et la douleur.

OBS

TRP : L'abréviation «TRP» provient du terme anglais «transient receptor potential».

Spanish

Save record 1

Record 2 2004-10-05

English

Subject field(s)
  • Viral Diseases
DEF

The spectrum of immunodeficiency and disease associated with HIV infection.

OBS

Characterized by a gradual deterioration of immune function. During the course of infection, crucial immune cells called CD4+ T cells are disabled and killed, and their numbers progressively decline. CD4+ T cells play a crucial role in the immune response, signaling other cells in the immune system to perform their special functions.

OBS

The term AIDS is used to indicate only the most severe diseases or clinical conditions (i.e., infections, neoplasm) observed in the continuum of illness related to infection with the retrovirus human immunodeficiency virus type 1 (HIV-1). Infection with HIV and AIDS are not synonymous terms.

Key term(s)
  • infection with HIV

French

Domaine(s)
  • Maladies virales
OBS

Classification des infections à V.I.H. Les conséquences de l'infection par le V.I.H. ne se limitent pas à la forme majeure de cette infection : le S.I.D.A. Par le passé, des formes intermédiaires ont été décrites dénommées par des termes imparfaits de pré-S.I.D.A. ou de para-S.I.D.A.; celui qui s'est imposé le plus longtemps est celui d'A.R.C. (A.I.D.S. related complex).

CONT

personne susceptible de contracter l'infection au VIH

Key term(s)
  • infection à V.I.H.
  • infection par le V.I.H.
  • infection au VIH

Spanish

Campo(s) temático(s)
  • Enfermedades víricas
OBS

La infección comienza cuando el virus encuentra a una célula CD4; entonces la glucoproteína 120 (Gp120) de la superficie del VIH se une estrechamente al receptor CD4 en la superficie de la célula; las membranas del virus y la célula se fusionan con la intervención de otra glucoproteína de la superficie del virus, llamada Gp41, para que las proteínas, enzimas y el corazón viral que contiene el RNA del VIH, sean introducidas en la célula ahora infectada.

Key term(s)
  • infección con VIH
  • infección del VIH
Save record 2

Record 3 2001-06-06

English

Subject field(s)
  • Biotechnology
CONT

Molecular Neuroscience includes the Neurobiotechnology faculty as well as other individual investigators from the Colleges of Biological Sciences, Dentistry, Medicine, Pharmacy, and Social and Behavioral Sciences. The projects in molecular neuroscience range from studies aimed at understanding the regulation of gene expression in nervous tissue to elucidating the molecular mechanisms that regulate nervous system function which are illustrated in the following areas : cell signaling mechanisms, neural degeneration, neuronal adhesion, nervous system development, aging, tumorigenesis, synapse formation, the developmental regulation of neurotransmitter peptides and receptor gene expression, genetics of neurological diseases and developmental biology of limb formation and regeneration.

French

Domaine(s)
  • Biotechnologie
CONT

Empêcher la mort des neurones, ou les remplacer par d'autres cellules. Telles sont les deux grandes voies de recherche proposées par des neurobiotechnologies encore balbutiantes, mais dont on attend beaucoup pour lutter contre les maladies neurodégénératives et mentales.

Spanish

Save record 3

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