TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

An effect resulting from a treatment that differs from its intended therapeutic effect.  3, record 1, English, - side%20effect

Record number: 1, Textual support number: 1 OBS

A side effect may be harmful, unpleasant or beneficial.  3, record 1, English, - side%20effect

Record number: 1, Textual support number: 2 OBS

This can be an effect carried beyond the desired limit, as hemorrhaging from an anticoagulant, or a reaction unrelated to the primary object of the therapy, as an anaphylactic reaction to an antibiotic. Usually, although not necessarily, the effect is undesirable, and may manifest itself as nausea, dry mouth, dizziness, blood dyscrasias, blurred vision, discolored urine, or tinnitus.  4, record 1, English, - side%20effect

Record number: 1, Textual support number: 3 OBS

side effect: designation standardized by the Health Technology Assessment (HTA) Glossary English Editorial Board and the Translation Bureau.  5, record 1, English, - side%20effect

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Effet d'un traitement qui diffère de l'effet thérapeutique recherché.  2, record 1, French, - effet%20secondaire

Record number: 1, Textual support number: 1 OBS

Un effet secondaire peut être néfaste, désagréable ou bénéfique.  2, record 1, French, - effet%20secondaire

Record number: 1, Textual support number: 2 OBS

effet secondaire : désignation normalisée par l'Institut national d'excellence en santé et en services sociaux (INESSS) et le Bureau de la traduction.  3, record 1, French, - effet%20secondaire

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Acción no deseada que producen algunos medicamentos, como anemia, dolor de cabeza, cansancio, náusea, fatiga, gastritis, neutropenia, pancreatitis, prurito, alopecia y muchos más; normalmente estos efectos desaparecen al suspender la administración de los medicamentos que los producen.  2, record 1, Spanish, - efecto%20secundario

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 OBS

Cavalier Therapeutic Riding Club is designed for people with various disabilities, as a therapy tool. Using the horses’ repetitive movement, various muscles and skeletal systems are rejuvenated and the emotional/disciplinary aspect is reinforced. Cavalier Therapeutic Riding Club has been in effect for 30 years and... is a non profit organization.  3, record 2, English, - Cavalier%20Riding%20Club

Record number: 2, Textual support number: 2 OBS

What makes CRC special is that [it] not only [offers] a different type of therapy, known as hippotherapy, but [it] also [teaches its] riders how to ride ...  4, record 2, English, - Cavalier%20Riding%20Club

Record 2,  Textual support,  French

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

A substance used in controlled experiments(such as a double-blind study of a drug) that has no therapeutic effect on the condition being treated but may produce side effects(such as drowsiness or nausea) similar to those of the substance whose effectiveness is being tested.  1, record 3, English, - active%20placebo

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Un placebo actif est un vrai médicament qui produit des effets secondaires mais n'est pas censé avoir de bénéfices thérapeutiques pour la maladie qu'il traite. Il est utilisé pour empêcher les patients dans les essais cliniques de lever l'insu – c'est-à-dire, de deviner le groupe auquel ils ont été assignés sur base des effets secondaires.  3, record 3, French, - placebo%20actif

Record number: 3, Textual support number: 1 OBS

placébo : Cette graphie, puisée des Rectifications de l'orthographe recommandées par le Conseil supérieur de la langue française, est attestée dans le Petit Robert (2004).  2, record 3, French, - placebo%20actif

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

A study of the therapeutic effect of a technology through comparison of the results of multiple measurements taken before and after the technology is used in a given group of subjects.  1, record 4, English, - interrupted%20time%20series

Record number: 4, Textual support number: 1 OBS

The value of this type of study can be strengthened by the addition of a control group in which the technology has not been tried and which is observed at the same points in time. Also, multiple time series can be studied by staggering the introduction of the technology.  1, record 4, English, - interrupted%20time%20series

Record number: 4, Textual support number: 2 OBS

interrupted time series: noun used with a singular verb.  2, record 4, English, - interrupted%20time%20series

Record number: 4, Textual support number: 3 OBS

interrupted time series: term and definition standardized by the Health Technology Assessment (HTA) Glossary English Editorial Board and the Translation Bureau.  3, record 4, English, - interrupted%20time%20series

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Étude de l’effet thérapeutique d’une technologie par la comparaison des résultats des multiples mesures prises avant et après son utilisation auprès d’un groupe de sujets donné.  1, record 4, French, - %C3%A9tude%20de%20s%C3%A9ries%20temporelles%20interrompues

Record number: 4, Textual support number: 1 OBS

La valeur de ce type d’étude peut être renforcée par l’ajout d’un groupe témoin n'ayant pas fait l’essai de la technologie qui est observé aux mêmes moments. On peut également étudier plusieurs séries temporelles en échelonnant sur une certaine période l’introduction de la technologie.  1, record 4, French, - %C3%A9tude%20de%20s%C3%A9ries%20temporelles%20interrompues

Record number: 4, Textual support number: 2 OBS

étude de séries temporelles interrompues; étude sérielle : termes et définition normalisés par l'Institut national d'excellence en santé et en services sociaux (INESSS) et le Bureau de la traduction.  2, record 4, French, - %C3%A9tude%20de%20s%C3%A9ries%20temporelles%20interrompues

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

A nano-object with all three external dimensions in the nanoscale.  2, record 5, English, - nanoparticle

Record number: 5, Textual support number: 1 CONT

In biomedical applications nanoparticles are used as drug carriers or imaging agents. For this purpose the nanoparticle may have a hollow structure providing a central reservoir that can be filled with anticancer drugs, detection agents, or chemicals, known as "reporters, "that can signal if a drug is having a therapeutic effect. The surface of a nanoparticle can also be adorned with various targeting agents, such as antibodies, drugs, imaging agents, and reporters. Most nanoparticles are constructed to be small enough to pass through blood capillaries and enter cells.  3, record 5, English, - nanoparticle

Record number: 5, Textual support number: 2 CONT

Nanoparticles that are naturally occurring (e.g. volcanic ash, soot from forest fires) or are the incidental byproducts of combustion processes (e.g. welding, diesel engines) [and] are usually physically and chemically heterogeneous and often termed "ultrafine particles." Engineered nanoparticles are intentionally produced and designed with very specific properties related to shape, size, surface properties and chemistry. These properties are reflected in aerosols, colloids or powders.  4, record 5, English, - nanoparticle

Record number: 5, Textual support number: 1 OBS

Nanoparticles are thus larger than angstroms (Å), but smaller than micrometres. At the small end of the size range, nanoparticles are often referred to as clusters (physics).  3, record 5, English, - nanoparticle

Record number: 5, Textual support number: 2 OBS

If the lengths of the longest to the shortest axes of the nano-object differ significantly (typically by more than three times), the term "nanofibre" or "nanoplate" is intended to be used instead of the term "nanoparticle."  2, record 5, English, - nanoparticle

Record number: 5, Textual support number: 3 OBS

nanoparticle: term and definition standardized by the International Organization for Standardization (ISO).  5, record 5, English, - nanoparticle

Record number: 5, Textual support number: 1 PHR

Core-shell, magnetic, metal, viral nanoparticle.  6, record 5, English, - nanoparticle

Record number: 5, Textual support number: 2 PHR

Nanoparticule formation, seeding, suspension, synthesis.  6, record 5, English, - nanoparticle

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Nano-objet dont les trois dimensions externes sont à la nano-échelle.  4, record 5, French, - nanoparticule

Record number: 5, Textual support number: 1 CONT

Les nanoparticules se situent à la frontière entre la matière à l'échelle macroscopique et [la matière] à l'échelle atomique ou moléculaire. Elles ont un intérêt à la fois fondamental et appliqué et sont très étudiées actuellement. De nombreux physiciens et chimistes les synthétisent, d'autres physiciens les étudient afin de comprendre la physique de ces objets nanométriques, et des biologistes les utilisent comme marqueurs cellulaires.  5, record 5, French, - nanoparticule

Record number: 5, Textual support number: 1 OBS

Si les valeurs de la plus longue dimension et de la plus courte dimension du nano-objet diffèrent de façon significative (généralement d'un facteur plus grand que trois), on utilise le terme «nanofibre» ou «nanofeuillet» à la place du terme «nanoparticule».  4, record 5, French, - nanoparticule

Record number: 5, Textual support number: 2 OBS

nanoparticule : terme et définition normalisés par l'Organisation internationale de normalisation (ISO).  6, record 5, French, - nanoparticule

Record number: 5, Textual support number: 1 PHR

Habillage sur mesure d'une nanoparticule.  7, record 5, French, - nanoparticule

Record number: 5, Textual support number: 2 PHR

Nanoparticule agrégée, conductrice, fabriquée artificiellement, isolée, semi-conductrice.  7, record 5, French, - nanoparticule

Record number: 5, Textual support number: 3 PHR

Nanoparticule offrant une plus grande surface d'échange, permettant de renforcer l'intensité aromatique.  7, record 5, French, - nanoparticule

Record number: 5, Textual support number: 4 PHR

Nanoparticule de séléniure de cadmium (CdSe).  7, record 5, French, - nanoparticule

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 CONT

Si las tres dimensiones de un material están en la nanoescala, hablamos de nanopartículas; si dos de sus dimensiones lo están, tenemos nanocables o nanovarillas, y si solo una de sus dimensiones pertenece a esa escala, tenemos películas delgadas.  1, record 5, Spanish, - nanopart%C3%ADcula

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 CONT

Benzatropine is an anticholinergic medication used for treating Parkinsons illness and related conditions such as parkinsonism, dystonia, and akathasia. Its effects have been shown to have an effective and significant therapeutic value in the management of the symptoms of parkinsonism. It counteracts the effects of the neurotransmitter acetylcholine and balances the levels of acetylcholine and dopamine in the body, which may help reduce the symptoms of Parkinson's illness in its early stages. It can also be used to treat movement disorders resulting from the use of other antipsychotic medication. Aside from its anticholinergic effect, doctors have also observed an antihistaminic activity approaching that of pyrilamine maleate.  2, record 6, English, - benzatropine

Record number: 6, Textual support number: 1 OBS

Active ingredient commonly sold under the name Akitan.  3, record 6, English, - benzatropine

Record number: 6, Textual support number: 2 OBS

Chemical formula: C₂₁H₂₅NO  3, record 6, English, - benzatropine

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Les anticholinergiques (atropine, benzatropine, trihexiphénidyle, etc.) s'opposent à l'action du système nerveux végétatif parasympathique en se fixant sur les récepteurs des cellules nerveuses à la place de l'acétylcholine. Ils sont prescrits dans le traitement des excès de sécrétion gastrique, des vomissements, de la maladie de Parkinson et administrés par voie orale ou par injection.  2, record 6, French, - benzatropine

Record number: 6, Textual support number: 1 OBS

Principe actif couramment commercialisé sous le nom de Akitan.  3, record 6, French, - benzatropine

Record number: 6, Textual support number: 2 OBS

Formule chimique : C₂₁H₂₅NO  3, record 6, French, - benzatropine

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

Treatment of behavior disorders in which two or more patients and the psychotherapist participate to resolve difficulties and effect therapeutic changes.  2, record 7, English, - group%20psychotherapy

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 DEF

Psychothérapie [...] qui permet de traiter simultanément plusieurs malades avec l'aide d'un ou plusieurs thérapeutes par utilisation des réactions inter-psychologiques [...]  1, record 7, French, - psychoth%C3%A9rapie%20de%20groupe

Record number: 7, Textual support number: 1 OBS

thérapie de groupe : Source - base de données PASCAL. Terme parfois utilisé comme synonyme de «psychothérapie de groupe», quoique différent dans le contexte de dynamiques de groupe.  2, record 7, French, - psychoth%C3%A9rapie%20de%20groupe

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 DEF

An inactive treatment or procedure that is intended to mimic as closely as possible a therapy in a clinical trial.  1, record 8, English, - placebo%20therapy

Record number: 8, Textual support number: 1 CONT

The ideal sham therapy is indistinguishable from the experimental therapy but could not have therapeutic effect.  3, record 8, English, - placebo%20therapy

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

On fait l'expérience une fois avec la thérapie à tester (groupe test), et une autre fois - avec un autre groupe - en utilisant une «thérapie placebo» (groupe témoin).  1, record 8, French, - th%C3%A9rapie%20placebo

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

Another example for saturable metabolism is phenytoin. The therapeutic range of phenytoin is usually given as 10 to 20 mg/L, but due to saturable elimination the difference between doses that result in a subtherapeutic effect and doses that cause toxicity is very small.  3, record 9, English, - saturable%20metabolism

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 CONT

La phénytoïne subit son catabolisme par l'action des enzymes hépatiques du cytochrome P450 et, à cause d'un métabolisme saturable, elle est très vulnérable aux interactions médicamenteuses inhibitrices. L'inhibition du métabolisme peut provoquer des élévations importantes des concentrations de phénytoïne circulante et augmenter ainsi le risque d'intoxication médicamenteuse.  2, record 9, French, - m%C3%A9tabolisme%20saturable

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 CONT

No drug known is completely specific in the sense of acting on exclusively one type of cell or tissue, to produce only one type of effect. However, the therapeutic usefulness of a drug is usually directly related to its degree of specificity.  2, record 10, English, - specificity

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 CONT

La spécificité d'un médicament signifie que son action est particulièrement efficace sur une seule maladie.  1, record 10, French, - sp%C3%A9cificit%C3%A9

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

Multifunctional nano-devices based on dendritic polymer components will be developed that target neoplastic cells and sense the earliest signatures of cancer. The dendritic nano-devices will be designed to support the specific release of a therapeutic agent within a tumor, and analyze the effect of the therapeutic identifying evidence of residual disease.  2, record 11, English, - dendritic%20polymer

Record number: 11, Textual support number: 2 CONT

Dendritic polymers containing disulfide functional groups which are essentially inert under non-reducing conditions, but which form sulfhydryl groups upon being subjected to a reducing agent are prepared by synthesizing dendritic polymers having a core with a disulfide linkage or by reacting a dendritic polymer with a molecule containing a disulfide linkage and reactive terminal groups.  3, record 11, English, - dendritic%20polymer

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 DEF

Polymère présentant une structure fractale formée de ramifications successives qui, en se développant à partir d'une molécule centrale, forme une sphérule.  1, record 11, French, - dendrim%C3%A8re

Record number: 11, Textual support number: 1 CONT

La surface extérieure des sphérules de dendrimères compte une infinité d'extrémités qui constituent autant de point d'ancrage. Cette particularité pourrait être utilisée pour améliorer les propriétés des lubrifiants, augmenter la transformabilité des plastiques, etc. De plus, les ramifications de la molécule ménagent des espaces pouvant abriter d'autres substances qui sont ensuite relâchées plus ou moins rapidement. C'est pourquoi on pense utiliser des dendrimères pour la libération contrôlée de médicaments. On a constaté aussi que l'ADN s'enroulait autour de certains dendrimères, qui pourraient ainsi servir au transport de gènes en thérapie génique.  1, record 11, French, - dendrim%C3%A8re

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 DEF

The dose of a drug that produces the intended therapeutic effect.  3, record 12, English, - effective%20dose

Record 12,  Textual support,  French

Record 12,  Textual support,  Spanish

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 DEF

Opposition in therapeutic effect between two or more medicines.  1, record 13, English, - therapeutic%20incompatibility

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 DEF

Propriété que peuvent avoir deux médicaments qui, lorsqu'ils sont mélangés, se neutralisent l'un l'autre.  1, record 13, French, - incompatibilit%C3%A9%20th%C3%A9rapeutique

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 DEF

Method of psychotherapy in which the therapeutic effect sought is "purgative" : an adequate discharge of pathogenic affects. The treatment allows the patient to evoke and even to relive the traumatic events to which these affects are bound, and to abreact them.  2, record 14, English, - cathartic%20method

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Toute méthode thérapeutique qui vise à obtenir une situation de crise émotionnelle telle que cette manifestation critique provoque une solution du problème que la crise met en scène.  1, record 14, French, - m%C3%A9thode%20cathartique

Record 14,  Textual support,  Spanish

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 CONT

Duration of drug action. It is usually assumed that a drug is effective when its concentration in the central compartment is greater than a minimal, threshold level(C/effective). C/effective may not be identical to C/therapeutic which is the concentration to achieve a specific therapeutic effect. Consequently, drug action is maintained as long as this condition of exceeding the minimum effective concentration is fulfilled.  1, record 15, English, - duration%20of%20drug%20action

Record 15,  Textual support,  French

Record number: 15, Textual support number: 1 CONT

Le chlorpropamide qui a une durée d'action de 24 à 60 heures n'est pas recommandé chez les personnes âgées.  1, record 15, French, - dur%C3%A9e%20d%27action

Record 15,  Textual support,  Spanish

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 CONT

In addition to the possibility of improved therapeutic effect for an individual patient, long-acting neuroleptic drugs offer a guaranteed delivery system of the agent.  1, record 16, English, - long%2Dacting%20neuroleptic%20drug

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 CONT

Les neuroleptiques à action prolongée résultent en général de l'estérification par un acide gras d'une fonction alcool primaire des neuroleptiques d'origine (...). L'action prolongée de ces esters est due à leur libération lente à partir de la solution huileuse injectée.  1, record 16, French, - neuroleptique%20%C3%A0%20action%20prolong%C3%A9e

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 CONT

When medication is administered to the patient so that his body is given an opportunity to respond, the medication is said to be made biologically available. If for some reason the drug is not made available, the desired therapeutic effect cannot be induced.  1, record 17, English, - desired%20therapeutic%20effect

Record number: 17, Textual support number: 2 CONT

Conservative drug therapy is designed to strengthen the vital powers of the patient's own defense mechanisms. Therefore, always administer the smallest amount of the least potent drug that will achieve the desired therapeutic effect.  1, record 17, English, - desired%20therapeutic%20effect

Record 17,  Textual support,  French

Record number: 17, Textual support number: 1 CONT

(...) ce qui importe en dernière analyse, c'est le nombre de molécules actives qui vont arriver en un point donné de l'organisme pour y exercer l'effet thérapeutique recherché (...) (les performances que l'on souhaite atteindre (...).  1, record 17, French, - effet%20th%C3%A9rapeutique%20recherch%C3%A9

Record number: 17, Textual support number: 2 CONT

Les voies d'administration des médicaments sont évidemment nombreuses et le choix de l'une d'entre elles dépend de l'effet thérapeutique recherché.  2, record 17, French, - effet%20th%C3%A9rapeutique%20recherch%C3%A9

Record 17,  Textual support,  Spanish