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THROMBOCYTOPENIA [14 records]

Record 1 2025-07-10

English

Subject field(s)
  • Human Diseases - Various
  • Blood
  • Immunology
CONT

The researchers who studied the German and Austrian patients... had initially called the syndrome vaccine-induced prothrombotic immune thrombocytopenia; [two teams of researchers] now suggest a slightly simpler name : vaccine-induced immune thrombotic thrombocytopenia(VITT).

OBS

... the patients had unusual antibodies that trigger clotting reactions, which use up the body's platelets and can block blood vessels, leading to potentially deadly strokes or embolisms. The symptoms resemble a rare reaction to the drug heparin, called heparin-induced thrombocytopenia(HIT), in which the immune system makes antibodies to a complex of heparin and a protein called platelet factor 4(PF4), triggering platelets to form dangerous clots throughout the body.

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
  • Immunologie

Spanish

Campo(s) temático(s)
  • Enfermedades humanas varias
  • Sangre
  • Inmunología
CONT

La trombocitopenia trombótica inmunitaria inducida por vacunas (VITT, por sus siglas en inglés) se define como un síndrome clínico caracterizado por todas las anomalías de laboratorio y radiológicas descritas a continuación que ocurren en individuos de 4 a 30 días después de la vacunación con Ad26.COV2 (Johnson & Johnson) o ChAdOx1 nCoV-19(Oxford-A. Zeneca).

Save record 1

Record 2 2025-02-26

English

Subject field(s)
  • Symptoms (Medicine)
  • Blood
CONT

Thrombocytopenia is a condition in which you have a low blood platelet count. Platelets(thrombocytes) are colorless blood cells that help blood clot.

OBS

Thrombocytopenia means you have fewer than 150, 000 platelets per microliter of circulating blood.

Key term(s)
  • thrombocytopaenia
  • thrombopaenia

French

Domaine(s)
  • Symptômes (Médecine)
  • Sang
DEF

Diminution du nombre de plaquettes au-dessous de 150 000 par mm³ de sang circulant [...]

Spanish

Campo(s) temático(s)
  • Síntomas (Medicina)
  • Sangre
DEF

Descenso del nivel de plaquetas por debajo de ciertos parámetros.

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Record 3 2024-12-17

English

Subject field(s)
  • Human Diseases - Various
  • Blood
  • Medication
CONT

Ordinarily, heparin prevents clotting and does not affect the platelets, components of the blood that help form blood clots. Triggered by the immune system in response to heparin, HIT causes a low platelet count(thrombocytopenia).

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
  • Médicaments

Spanish

Campo(s) temático(s)
  • Enfermedades humanas varias
  • Sangre
  • Medicamentos
DEF

Reacción adversa protrombótica, mediada por activación de anticuerpos antiplaquetarios (mayoritariamente IgG [inmonoglobulinas G) contra el complejo formado por el factor plaquetario y la heparina, en individuos en tratamiento con este fármaco.

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Record 4 2023-07-21

English

Subject field(s)
  • Animal Diseases
  • Horse Husbandry
CONT

Equine infectious anemia(EIA), also known as "swamp fever, "is an infectious disease of horses and other equids characterized by recurrent episodes of fever, lethargy, inappetence, thrombocytopenia, and anemia.

French

Domaine(s)
  • Maladies des animaux
  • Élevage des chevaux
CONT

L'anémie infectieuse des équidés (AIE), appelée jadis fièvre des marais, est une virose infectieuse qui peut être mortelle. Le virus de l'anémie infectieuse des équidés (AIE) appartient à la famille des «Retroviridae», genre «Lentivirus». La maladie affecte les chevaux, mais aussi d'autres équidés comme les ânes et les mulets. Cette infection persistante se caractérise par les symptômes suivants : fièvre, dépression, faiblesse progressive, amaigrissement, œdèmes des membres et de l'abdomen, anémie. La plupart des chevaux atteints sont asymptomatiques; ils demeurent néanmoins porteurs du virus toute leur vie et constituent ainsi une source d'infection pour les animaux sensibles.

Spanish

Campo(s) temático(s)
  • Enfermedades de los animales
  • Cría de ganado caballar
Save record 4

Record 5 2021-10-22

English

Subject field(s)
  • Human Diseases - Various
  • Blood
  • Medication
CONT

Heparin-induced thrombocytopenia with thrombosis(HITT) is a paradoxical prothrombotic complication of anticoagulant therapy. As many as 3% of patients undergoing cardiac surgery develop clinical HIT [heparin-induced thrombocytopenia] presenting as thrombocytopenia with or without thrombosis within 5–10 days of heparin exposure. Thrombotic complications associated with HIT carry a mortality rate of 5–10%.

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
  • Médicaments

Spanish

Save record 5

Record 6 2017-12-06

English

Subject field(s)
  • Blood
OBS

Cf. "Improved assay for detection of platelet specific PLA1 antibodies in neonatal alloimmune thrombocytopenia". Vox Sanguinis, 1982, vol. 43, pp. 76-81.

Key term(s)
  • neonatal allo-immune thrombocytopenia

French

Domaine(s)
  • Sang
CONT

Les thrombopénies néonatales allo-immunes (TNA) sont dues à une immunisation de la mère contre des antigènes portés par les plaquettes du fœtus. Dans la majorité des accidents, c'est le système PLA OU ZW qui est en cause, une femme de groupe PLA1 négatif développe un anticorps contre l'antigène PLA1 de son fœtus.

OBS

thrombopénie néonatale alloimmune : Source : Revue française de transfusion et immuno-hématologie, vol. 28, 1985, n° 6, p. 625.

Spanish

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Record 7 2012-01-31

English

Subject field(s)
  • Blood
DEF

The attachment or clumping of platelets together.

CONT

In Glanzmann's thrombocytopenia, two membrane glycoproteins(GPIIb-IIIa) that normally serve as the receptor for fibrinogen in activated platelets are markedly deficient. Fibrinogen binding to platelets is required for platelet aggregation.

French

Domaine(s)
  • Sang
DEF

Processus par lequel des thrombocytes se fixent les uns aux autres de façon à former un agrégat (collection).

Spanish

Campo(s) temático(s)
  • Sangre
Save record 7

Record 8 2011-01-19

English

Subject field(s)
  • Immunology
CONT

SLE is a disease of unknown cause that may produce variable combinations of fever, rashes, hair loss, arthritis, pleuritis, pericarditis, nephritis, anemia, leukopenia, thrombocytopenia, and central nervous system(CNS) disease. The clinical course is characterized by periods of remissions and acute or chronic relapses. Patients with SLE develop characteristic immune abnormalities, especially antibodies to a number of nuclear and other cellular antigens.

French

Domaine(s)
  • Immunologie
CONT

Le lupus érythémateux disséminé ou systémique (encore appelé maladie lupique) est une maladie inflammatoire chronique d'origine inconnue et qui affecte la peau, les articulations, le rein, les poumons, le système nerveux, les séreuses et/ou d'autres organes. Il est associé à des anomalies immunologiques spécifiques notamment la production de certains anticorps anti-nucléaires.

Key term(s)
  • LES
  • LED

Spanish

Campo(s) temático(s)
  • Inmunología
Save record 8

Record 9 2009-04-08

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
OBS

An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects.

OBS

Chemical formula: C11H12N2S

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
OBS

Formule chimique : C11H12N2S

Spanish

Campo(s) temático(s)
  • Elementos y compuestos químicos
  • Medicamentos
Entrada(s) universal(es)
Save record 9

Record 10 2006-05-08

English

Subject field(s)
  • Immunology
DEF

A combination of chronic(rheumatoid) arthritis, splenomegaly, leukopenia, pigmented spots on the skin of the lower extremities, and other inconsistent evidence of hypersplenish, namely, anemia and thrombocytopenia.

French

Domaine(s)
  • Immunologie
DEF

Association d'une polyarthrite rhumatoïde, d'une splénomégalie et d'une neutropénie.

Spanish

Campo(s) temático(s)
  • Inmunología
Save record 10

Record 11 2004-11-02

English

Subject field(s)
  • Microbiology and Parasitology
DEF

Toxin that is released only after death of the bacterial cell. Nowadays the term is a synonym for the lipopolysaccharides (O antigen) of Gram-negative bacteria.

DEF

A substance containing lipopolysaccharide complexes found in the cell walls of microorganisms, principally gram-negative bacteria, associated with a wide variety of biological effects, such as fever, shock, transient leukopenia, and thrombocytopenia.

French

Domaine(s)
  • Microbiologie et parasitologie
DEF

Toxine liée au corps bactérien, libérée uniquement lors de la lyse de certaines bactéries à Gram négatif et constituée par l'antigène somatique situé dans la paroi de ces bactéries.

Spanish

Campo(s) temático(s)
  • Microbiología y parasitología
DEF

Toxina bacteriana que se libera sólo cuando la célula se desintegra.

OBS

Del griego endon: dentro de; toxikon: veneno

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Record 12 2002-04-24

English

Subject field(s)
  • Blood
DEF

A rare disease of unknown etiology, usually characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and neurologic abnormalities, fever, renal involvement, proteinuria, hematuria, azotemia, and casts.

French

Domaine(s)
  • Sang
CONT

Le purpura thrombopénique thrombotique, appelé aussi syndrome hémolytique et urémique ou PTT, est un trouble caractérisé par la coagulation anormale et la destruction des globules sanguins, entraînant ainsi une formation de caillots sanguins dans tout le corps.

Spanish

Save record 12

Record 13 2002-03-26

English

Subject field(s)
  • Blood
CONT

An autosomal dominant disorder associated with the presence of giant platelets, moderate thrombocytopenia and bright blue Döhle-body like inclusions in WBC [white blood cells] that are composed of parallel filaments.

Key term(s)
  • May-Hegglin's anomaly

French

Domaine(s)
  • Sang
CONT

L'anomalie de May-Hegglin est caractérisée par des plaquettes géantes et des anomalies polynucléaires qui présentent des corps de Döhle.

Spanish

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Record 14 1993-01-23

English

Subject field(s)
  • Immunology
CONT

Immunologic disorders of platelets are similar to those described for immunohemolytic anemias in which antiplatelet antibodies play a major role in several clinical disorders such as : acute idiopathic thrombocytopenic purpura, chronic idiopathic thrombocytopenic purpura, post-transfusion purpura, isoimmune neonatal thrombocy-topenia, and drug-induced thrombocytopenia.

CONT

Autoantibodies to platelets are seen in up to 70 % of cases of idiopathic thrombocytopenic purpura ....

French

Domaine(s)
  • Immunologie
CONT

Des anticorps antiplaquettaires peuvent également être retrouvés (par agglutination ou mieux par test de Dixon). Ils peuvent provoquer une thrombopénie et un purpura. (...) Purpuras (...) dus à la destruction des plaquettes sanguines par des autoanticorps antiplaquettes (...)

DEF

Les anticorps anti-plaquettes sont des anticorps dirigés contre les antigènes des plaquettes.

CONT

(Les) purpuras thrombopéniques idiopathiques sont dus à la destruction des plaquettes sanguines par des autoanticorps antiplaquettes.

Spanish

Save record 14

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