TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
TNF-ALPHA [4 records]
Record 1 - internal organization data 2021-02-26
Record 1, English
Record 1, Subject field(s)
- Cytology
- Immunology
- Medication
Record 1, Main entry term, English
- tumour necrosis factor
1, record 1, English, tumour%20necrosis%20factor
correct
Record 1, Abbreviations, English
- TNF 1, record 1, English, TNF
correct
Record 1, Synonyms, English
- tumor necrosis factor 2, record 1, English, tumor%20necrosis%20factor
correct
- TNF 3, record 1, English, TNF
correct
- TNF 3, record 1, English, TNF
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A protein produced by macrophages in response to bacterial infection ... 4, record 1, English, - tumour%20necrosis%20factor
Record number: 1, Textual support number: 1 CONT
Tumor necrosis factor(TNF) was originally discovered as a serum protein with necrotizing effects on certain transplantable mouse tumors in vivo and cytotoxic effects against some transformed cells in vitro. The TNF family consists of two proteins designated TNF-alpha, also called cachectin, and TNF-beta, also called lymphotoxin, which are pleiotropic cytokines that can mediate a wide variety of biological effects. TNF-beta is produced by activated lymphocytes, whereas TNF-alpha is mostly produced by activated macrophages. 5, record 1, English, - tumour%20necrosis%20factor
Record number: 1, Textual support number: 1 OBS
A form made by genetic engineering is used in [some treatments]. 4, record 1, English, - tumour%20necrosis%20factor
Record number: 1, Textual support number: 2 OBS
In specialized works, the term «tumour necrosis factor» often makes reference to the tumour necrosis factor alpha. 6, record 1, English, - tumour%20necrosis%20factor
Record 1, French
Record 1, Domaine(s)
- Cytologie
- Immunologie
- Médicaments
Record 1, Main entry term, French
- facteur de nécrose tumorale
1, record 1, French, facteur%20de%20n%C3%A9crose%20tumorale
correct, masculine noun
Record 1, Abbreviations, French
- TNF 2, record 1, French, TNF
correct, masculine noun
Record 1, Synonyms, French
- facteur nécrosant des tumeurs 3, record 1, French, facteur%20n%C3%A9crosant%20des%20tumeurs
correct, masculine noun
- TNF 4, record 1, French, TNF
correct, masculine noun
- TNF 4, record 1, French, TNF
- facteur de nécrose des tumeurs 5, record 1, French, facteur%20de%20n%C3%A9crose%20des%20tumeurs
correct, masculine noun
- TNF
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Au cours des dernières années, on a mis en évidence un nombre croissant de protéines intervenant dans l'inflammation et l'immunité comme la croissance et l'inhibition cellulaires. Ces protéines, auxquelles on a donné le nom général de cytokines, comprennent […] le TNF […] 4, record 1, French, - facteur%20de%20n%C3%A9crose%20tumorale
Record number: 1, Textual support number: 1 OBS
[…] on connaît actuellement la séquence du TNF de plusieurs espèces et on le fabrique par génie génétique. 4, record 1, French, - facteur%20de%20n%C3%A9crose%20tumorale
Record number: 1, Textual support number: 2 OBS
Dans les ouvrages spécialisés, le terme «facteur de nécrose tumorale» fait souvent référence au facteur de nécrose tumorale alpha. 7, record 1, French, - facteur%20de%20n%C3%A9crose%20tumorale
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Citología
- Inmunología
- Medicamentos
Record 1, Main entry term, Spanish
- factor de necrosis tumoral
1, record 1, Spanish, factor%20de%20necrosis%20tumoral
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- factor de necrosis del tumor 2, record 1, Spanish, factor%20de%20necrosis%20del%20tumor
correct, masculine noun
- FNT 2, record 1, Spanish, FNT
correct, masculine noun
- FNT 2, record 1, Spanish, FNT
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Polipéptido que interviene en los mecanismos reguladores inmunológicos, eliminando o inhibiendo el crecimiento de ciertas células tumorales. 1, record 1, Spanish, - factor%20de%20necrosis%20tumoral
Record number: 1, Textual support number: 1 OBS
Sustancia producida por los macrófagos que tiene la capacidad de destruir células cancerígenas. 2, record 1, Spanish, - factor%20de%20necrosis%20tumoral
Record 2 - internal organization data 2020-09-30
Record 2, English
Record 2, Subject field(s)
- Cytology
- Immunology
Record 2, Main entry term, English
- tumor necrosis factor-beta
1, record 2, English, tumor%20necrosis%20factor%2Dbeta
correct
Record 2, Abbreviations, English
- TNF-beta 1, record 2, English, TNF%2Dbeta
correct
Record 2, Synonyms, English
- TNF-beta 2, record 2, English, TNF%2Dbeta
correct
- lymphotoxin 1, record 2, English, lymphotoxin
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
The TNF [tumor necrosis factor] family consists of two proteins designated TNF-alpha [that is mostly produced by activated macrophages, and] TNF-beta [that] is produced by activated lymphocytes... 2, record 2, English, - tumor%20necrosis%20factor%2Dbeta
Record 2, Key term(s)
- tumour necrosis factor beta
Record 2, French
Record 2, Domaine(s)
- Cytologie
- Immunologie
Record 2, Main entry term, French
- facteur de nécrose tumorale bêta
1, record 2, French, facteur%20de%20n%C3%A9crose%20tumorale%20b%C3%AAta
correct, masculine noun
Record 2, Abbreviations, French
- TNF-ß 1, record 2, French, TNF%2D%C3%9F
correct, masculine noun
Record 2, Synonyms, French
- facteur nécrosant les tumeurs bêta 2, record 2, French, facteur%20n%C3%A9crosant%20les%20tumeurs%20b%C3%AAta
correct, masculine noun
- TNF bêta 3, record 2, French, TNF%20b%C3%AAta
correct, masculine noun
- TNF-bêta 4, record 2, French, TNF%2Db%C3%AAta
correct, masculine noun
- lymphotoxine 5, record 2, French, lymphotoxine
correct, feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Les facteurs nécrosant les tumeurs font partie des cytokines. Il en existe deux : le TNF alpha […] et le TNF bêta, ou lymphotoxine, produit par les lymphocytes T activés. 3, record 2, French, - facteur%20de%20n%C3%A9crose%20tumorale%20b%C3%AAta
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Citología
- Inmunología
Record 2, Main entry term, Spanish
- factor de necrosis tumoral ß
1, record 2, Spanish, factor%20de%20necrosis%20tumoral%20%C3%9F
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
- linfotoxina 1, record 2, Spanish, linfotoxina
correct, feminine noun
- LT 1, record 2, Spanish, LT
correct, feminine noun
- TNF-ß 1, record 2, Spanish, TNF%2D%C3%9F
correct, masculine noun
Record 2, Textual support, Spanish
Record 3 - internal organization data 2000-03-08
Record 3, English
Record 3, Subject field(s)
- Hormones
Record 3, Main entry term, English
- uromodulin
1, record 3, English, uromodulin
correct
Record 3, Abbreviations, English
- URO 1, record 3, English, URO
correct
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
Effects of uromodulin(URO) and Tamm-Horsfall protein(THP), the most abundant proteins in the urine of pregnant and normal women, respectively, on the induction of TNF-alpha secretion and tissue factor(TF) expression of human monocytes were studied. THP, URO, and its fragments stimulated human mononuclear cells to proliferate and secrete TNF-alpha. 1, record 3, English, - uromodulin
Record 3, French
Record 3, Domaine(s)
- Hormones
Record 3, Main entry term, French
- uromoduline
1, record 3, French, uromoduline
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Glycoprotéine isolée et purifiée, à partir de l'urine de femmes enceintes, ayant des propriétés immunosuppressives : elle inhibe l'activité de certaines cellules impliquées dans l'immunité, notamment les lymphocytes T et les monocytes. 1, record 3, French, - uromoduline
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 1996-10-17
Record 4, English
Record 4, Subject field(s)
- Biochemistry
- Genetics
Record 4, Main entry term, English
- extracellular signal-regulated kinase
1, record 4, English, extracellular%20signal%2Dregulated%20kinase
correct
Record 4, Abbreviations, English
- ERK 2, record 4, English, ERK
correct
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
Insoluble peptidoglycan(PGN) from staphylococcal cell walls as well as soluble PGN(sPGN) secreted by staphylococci in the presence of beta-lactam antibiotics induced TNF-alpha mRNA and secretion of bioactive TNF-alpha in the murine RAW264. 7 macrophage cell line. PGN and sPGN also induced rapid and dose-dependent tyrosine phosphorylation of several cellular proteins, including lyn and mitogen-activated protein kinases(extracellular signal-regulated kinases; but not hck, fgr, or vav) and increased the activities of mitogen-activated protein and rsk kinases. These PGN-and sPGN-induced effects were qualitatively similar to the effects induced by ReLPS, but higher concentrations of PGN and sPGN than ReLPS were required. 3, record 4, English, - extracellular%20signal%2Dregulated%20kinase
Record number: 4, Textual support number: 1 OBS
The Journal of Immunology: Volume: 155 Number: 05 Pages: 2620 - 2630 September 1, 1995. 4, record 4, English, - extracellular%20signal%2Dregulated%20kinase
Record 4, French
Record 4, Domaine(s)
- Biochimie
- Génétique
Record 4, Main entry term, French
- protéine ERK
1, record 4, French, prot%C3%A9ine%20ERK
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record 4, Spanish
Record 4, Textual support, Spanish
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