TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

A screening test for syphilis using a cardiolipin antigen suspension to reveal to the naked eye an anti-lipid antibody caused by Treponema pallidum, the syphilis bacteria, in unheated serum or plasma.  2, record 1, English, - rapid%20plasma%20reagin%20test

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Test de dépistage de la syphilis qui utilise un antigène cardiolipidique pour rendre visible à l'œil nu la présence d'anticorps anti-lipidiques causés par la syphilis dans le sérum non chauffé ou le plasma.  4, record 1, French, - test%20rapide%20de%20la%20r%C3%A9agine%20plasmatique

Record number: 1, Textual support number: 1 OBS

Bien qu'on utilise souvent (le) «RPR» pour désigner la notion de «test RPR», il est préférable d'utiliser «test RPR» pour éviter toute confusion.  4, record 1, French, - test%20rapide%20de%20la%20r%C3%A9agine%20plasmatique

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

The standard nontreponemal antigen serologic test for syphilis [that consists of] a slide flocculation test using heat-inactivated serum and VDRL antigen, a standardized mixture of cardiolipin, lecithin, and cholesterol.  4, record 2, English, - VDRL%20test

Record number: 2, Textual support number: 1 CONT

Syphilitic infection leads to the production of nonspecific antibodies that react to cardiolipin. This reaction is the foundation of "non-treponemal" assays such as the VDRL(Venereal Disease Research Laboratory) test[, a] flocculation type [test that uses] an antigen-antibody interaction. The complexes remain suspended and therefore visible due to the lipid based antigens. With the VDRL a microscope is required... The VDRL assay detects an antibody against cardiolipin, a cellular membrane component that is released by cells when they are damaged by T. [Treponema] pallidum or in some other medical conditions.  3, record 2, English, - VDRL%20test

Record number: 2, Textual support number: 1 OBS

Although "VDRL" is widely used as synonym of "VDRL test," it is preferable to use the more precise terms to avoid any confusion.  5, record 2, English, - VDRL%20test

Record number: 2, Textual support number: 2 OBS

VDRL test: This term appears under the entry "test" in the Dorland’s illustrated medical dictionary.  5, record 2, English, - VDRL%20test

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Le diagnostic sérologique [de la syphilis] comprend un test de dépistage initial du sérum par des analyses non tréponémiques telles que le test VDRL (Venereal Disease Research Laboratory) [...]  3, record 2, French, - test%20VDRL

Record number: 2, Textual support number: 2 CONT

VDRL -- Il repose sur l'agglutination passive des anticorps dirigés contre l'antigène cardiolipidique fixé sur un support inerte constitué de cristaux de cholestérol. La formation de complexes antigènes-anticorps provoque la formation de floculats visibles au microscope, à faible grossissement. Le VDRL est simple, rapide et peu coûteux.  4, record 2, French, - test%20VDRL

Record number: 2, Textual support number: 1 OBS

Bien qu'on utilise souvent «VDRL» pour désigner la notion de «test VDRL», il est préférable d'utiliser «test VDRL» pour éviter toute confusion.  5, record 2, French, - test%20VDRL

Record 2,  Textual support,  Spanish

Record number: 2, Textual support number: 1 CONT

Prueba VDRL. En las personas seropositivas al VIH es importante la realización de este examen porque la presencia de otra ETS [enfermedades de transmisión sexual] puede activar al VIH, haciendo necesario dar de inmediato el tratamiento contra aquella.  1, record 2, Spanish, - prueba%20VDRL

Record number: 2, Textual support number: 1 OBS

VDRL por sus iniciales en inglés "Venereal Disease Research Laboratory".  2, record 2, Spanish, - prueba%20VDRL

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

[An] immunoassay in which an enzyme is used as a marker to indicate the presence of specific antigens, [or] antibodies ...  4, record 3, English, - enzyme%20immunoassay

Record number: 3, Textual support number: 1 CONT

Several enzyme immunoassays(EIA) have been developed commercially to detect IgG [immunoglobulin G] or IgM [immunoglobulin M] to specific T. [Treponema] pallidum antigens and are useful in HIV co-infected patients.  5, record 3, English, - enzyme%20immunoassay

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Épreuve fondée sur la spécificité de la réaction antigène-anticorps et dans laquelle une enzyme est utilisée à titre de marqueur pour déterminer la présence ou la quantité d'antigènes ou d'anticorps spécifiques.  5, record 3, French, - %C3%A9preuve%20immunoenzymatique

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

A blood serum screening test for syphilis designed to demonstrate the presence or absence of specific antibodies directed against the organism(Treponema pallidum) responsible for syphilis.  3, record 4, English, - fluorescent%20treponemal%20antibody%20absorption%20test

Record number: 4, Textual support number: 1 OBS

The "fluorescent treponemal antibody absorption test" is a Treponema-specific test.  5, record 4, English, - fluorescent%20treponemal%20antibody%20absorption%20test

Record number: 4, Textual support number: 2 OBS

... the test serum is absorbed with nonpathogenic treponemal organisms before incubation with fixed Treponema pallidum. This removes antibodies reactive with other organisms and leaves antibodies specifically indicative of a syphilitic infection.  6, record 4, English, - fluorescent%20treponemal%20antibody%20absorption%20test

Record number: 4, Textual support number: 3 OBS

FTA-ABS test: This term appears under the entry "test" in the International dictionary of medicine and biology.  5, record 4, English, - fluorescent%20treponemal%20antibody%20absorption%20test

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

Tests sérologiques de la syphilis [...] Il existe trois tests tréponémiques standard [dont] l'immunofluorescence (FTA-ABS)[.] Pour le test FTA-ABS, le sérum du malade est d'abord dilué avec une substance contenant des antigènes tréponémiques non pathogènes (absorbant) pour éliminer les anticorps spécifiques de groupe dirigés contre les tréponèmes saprophytes des cavités buccales et génitales. Le sérum ainsi absorbé est alors déposé sur une lame recouverte de T. [Treponema] pallidum fixés. Si l'anticorps spécifique de T. Pallidum est présent dans le sérum du patient, il se fixe aux tréponèmes séchés; sa mise en évidence se fait alors par l'adjonction d'anti-immunoglobulines humaines marquées à la fluorescine et examen de la lame au microscope à fluorescence. [...] le FTA-ABS [est un test très spécifique, et lorsqu'il est utilisé] pour confirmer des réactions réaginiques positives, [il a] une très haute valeur prédictive positive pour le diagnostic de la syphilis.  4, record 4, French, - test%20FTA%2DABS

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

Syphilis is a chronic infectious disease caused by the bacterium Treponema pallidum.  1, record 5, English, - Treponema%20pallidum

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

Le genre Treponema comprend de nombreuses espèces. [...] L'espèce pathogène par excellence est Treponema pallidum subspecies pallidum, l'agent de la syphilis, une des principales maladies vénériennes.  1, record 5, French, - Treponema%20pallidum

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 CONT

Coinfection [means] infection with more than one virus, bacterium, or other micro-organism at a given time. For example, an HIV-infected individual may be coinfected with hepatitis C virus (HCV) or tuberculosis (TB).  3, record 6, English, - coinfected

Record number: 6, Textual support number: 2 CONT

Several enzyme immunoassays(EIA) have been developed commercially to detect IgG [immunoglobulin G] or IgM [immunoglobulin M] to specific T. [Treponema] pallidum antigens and are useful in HIV co-infected patients.  2, record 6, English, - coinfected

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Lorsqu'une personne a le VIH et une autre infection grave comme l'hépatite C, on dit qu'elle est co-infectée.  3, record 6, French, - co%2Dinfect%C3%A9

Record number: 6, Textual support number: 2 CONT

Il existe sur le marché plusieurs essais immuno-enzymatiques (EIA) servant à déceler les IgG [immunoglobulines G] ou les IgM [immunoglobulines M] dirigées contre des antigènes spécifiques de T. [Treponema] pallidum; [ceux-ci] sont utiles chez les patients co-infectés par le VIH.  4, record 6, French, - co%2Dinfect%C3%A9

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

[A test] in which treponemal antigens or intact cells are used to detect specific anti-treponemal antibodies which occur in the serum of patients suffering from syphilis (or pinta or yaws).  5, record 7, English, - treponemal%20test

Record number: 7, Textual support number: 1 CONT

Treponema-specific tests... are used primarily to confirm the diagnosis of syphilis in patients with a reactive non-treponemal test.... Unlike non-treponemal tests, which show a decline in titers or become nonreactive with effective treatment, most treponema-specific tests usually remain reactive for life. Because of the persistence of reactivity, possibly for the life of the patient, treponemal tests are of no value to the clinician in determining relapse, reinfection, or treatment efficacy. Therefore, a reactive treponemal test result only indicates exposure to T. [Treponema] pallidum at some time during a person's life. It does not indicate that the person currently has an active syphilis infection. For this reason, a positive treponemal test result should be confirmed with a non-treponemal test.  3, record 7, English, - treponemal%20test

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

Les tests tréponémiques sont des épreuves plus spécifiques [que les tests non-tréponémiques] pour la syphilis. Il s'agit principalement des tests suivants : TP-PA (test d'agglutination de Treponema pallidum); FTA-ABS (test d'immunofluorescence absorbée); MHA-TP (réaction de microhémagglutination pour le Treponema pallidum). Tous ces tests sont basés sur la détection d'anticorps circulants dirigés contre des composantes antigéniques de T. pallidum. [...] ils sont généralement utilisés afin de confirmer la réactivité des tests non-tréponémiques.  4, record 7, French, - test%20tr%C3%A9pon%C3%A9mique

Record number: 7, Textual support number: 2 CONT

Les tests tréponémiques peuvent demeurer réactifs à vie chez les patients qui ont déjà présenté une syphilis ou une autre tréponématose, même traitée adéquatement.  5, record 7, French, - test%20tr%C3%A9pon%C3%A9mique

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

T. [Treponema] pallidum hemagglutination(TPHA) test and microhemagglutination-T. pallidum(MHA-TP) test. In the TPHA test the antigen is a suspension of formalin-treated sheep erythrocytes coated with T. Pallidum antigens. The patient's serum is purified of nonspecific heteroagglutins and then added to the suspension. Agglutination of the erythrocytes indicates the presence of specific antibodies... The microhemagglutination version is quite similar, but is assessed microscopically.  5, record 8, English, - MHA%2DTP%20test

Record number: 8, Textual support number: 1 OBS

A miniaturized form of the TPHA test.  3, record 8, English, - MHA%2DTP%20test

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

Examens diagnostiques [de la syphilis.] Le MHA-TP [...] est spécifique des anticorps anti-tréponème, mais il peut être négatif en cas de syphilis primaire.  4, record 8, French, - test%20de%20microh%C3%A9magglutination%20pour%20la%20d%C3%A9tection%20de%20Treponema%20pallidum

Record number: 8, Textual support number: 2 CONT

[Les réactions] tréponémiques [sont des tests] complémentaires utilisés pour confirmer les résultats des réactions non tréponémiques; [elles] permettent de détecter les anticorps dirigés contre les éléments cellulaires des tréponèmes. Citons entre autres : le test d'agglutination de Treponema pallidum (TP-PA) [...] et la réaction de microhémagglutination pour le Treponema pallidum (MHA-TP).  5, record 8, French, - test%20de%20microh%C3%A9magglutination%20pour%20la%20d%C3%A9tection%20de%20Treponema%20pallidum

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

The Treponema pallidum particle agglutination(TP-PA) test is a treponemal test(confirmation test) for the serologic detection of antibodies to the various species and subspecies of pathogenic Treponema, the causative agents of syphilis, yaws, pinta, bejel, and endemic syphilis. The test is a passive agglutination procedure based on the agglutination of gel particles sensitized with T. pallidum antigens by antibodies found in the patient's serum.  6, record 9, English, - Treponema%20pallidum%20particle%20agglutination%20test

Record number: 9, Textual support number: 2 CONT

Sera positive in non-treponemal tests are retested by treponemal assays such as the Treponema pallidum particle agglutination(TP-PA) test...  2, record 9, English, - Treponema%20pallidum%20particle%20agglutination%20test

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 DEF

Épreuve d'agglutination qui recherche des anticorps totaux de Treponema pallidum.  5, record 9, French, - test%20d%27agglutination%20passive%20de%20Treponema%20pallidum

Record number: 9, Textual support number: 1 CONT

Lorsque l'analyse non tréponémique est positive, on doit procéder à une confirmation par des analyses tréponémiques telles que le test d'agglutination passive de Treponema pallidum (TP-PA) [...].  6, record 9, French, - test%20d%27agglutination%20passive%20de%20Treponema%20pallidum

Record number: 9, Textual support number: 1 OBS

Le TPPA est un test d'agglutination, proche du TPHA (Treponema pallidum hemagglutination], mais les érythrocytes sont ici remplacés par des particules inertes.  3, record 9, French, - test%20d%27agglutination%20passive%20de%20Treponema%20pallidum

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 CONT

Syphilis is a communicable disease caused by Treponema pallidum, which belongs to the Spirochaetaceae family. [In] primary syphilis, the primary lesion, called a chancre, is painless but slightly tender. It usually develops at the site of the infection an average of 3 weeks after exposure to T pallidum. Patients may ignore a visible lesion because it is painless unless it becomes secondarily infected.  1, record 10, English, - primary%20syphilis

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 CONT

Syphilis primaire. La syphilis récente, stade le plus précoce, est marquée par l'apparition du chancre au point d'inoculation, accompagné de son adénopathie satellite.  1, record 10, French, - syphilis%20primaire

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

Tertiary syphilis is a late phase of the sexually transmitted disease syphilis, caused by the spirochete Treponema pallidum.  1, record 11, English, - tertiary%20syphilis

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 CONT

La syphilis tertiaire [...] survient en l'absence de traitement, après quelques mois ou années silencieuses. Elle est caractérisée par des atteintes neurologiques (on parle de neuro-syphilis), cardiaques, hépatiques, digestives, rénales, laryngées, oculaires, troubles psychiatriques. Pendant cette phase de la maladie [...] le patient n'est plus contagieux.  2, record 11, French, - syphilis%20tertiaire

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 DEF

... a chronic infectious disease caused by the bacterium Treponema pallidum. It is usually acquired by sexual contact with another infected individual.  3, record 12, English, - syphilis

Record 12,  Textual support,  French

Record number: 12, Textual support number: 1 DEF

[...] maladie infectieuse sexuellement transmissible, due à un spirochète "Treponema pallidum" (bactérie hélicoïdale mobile en vrille).  3, record 12, French, - syphilis

Record 12,  Textual support,  Spanish

Record number: 12, Textual support number: 1 DEF

Enfermedad transmitida usualmente por vía sexual, producida por una bacteria espiroqueta llamada Treponema pallidum.  3, record 12, Spanish, - s%C3%ADfilis

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 DEF

A syphilitic ulcer developing at the site of invasion of Treponema pallidum.  2, record 13, English, - chancre

Record number: 13, Textual support number: 2 DEF

A lesion, usually an ulcer, formed at the site of primary inoculation; generally, the initial lesion of syphilis or chancroid, or of such diseases as sporotrichosis and tularemia.  3, record 13, English, - chancre

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 DEF

Lésion cutanéomuqueuse de primo-invasion d'une affection microbienne, vénérienne ou tuberculeuse.  2, record 13, French, - chancre

Record number: 13, Textual support number: 1 OBS

Lorsqu'on parle de chancre sans autre précision, on entend généralement [...] le chancre syphilitique. [...] Il siège à l'endroit où l'agent pathogène (Treponema pallidum) a pénétré dans l'organisme.  3, record 13, French, - chancre

Record 13,  Textual support,  Spanish

Record number: 13, Textual support number: 1 DEF

Lesión provocada por una enfermedad de transmisión sexual, de la cual existen dos tipos: chancro blando y chancro duro.  3, record 13, Spanish, - chancro

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 CONT

The binding strength of antibodies to multivalent antigens, called avidity, is generally low in primary acute infections and increases in response to the maturation of the immune system. Measurement of avidity in serum dilutions is complicated and therefore, no avidity data are available in syphilis serology. By introduction of a solid phase elution method, avidity can be determined quickly using a sandwich ELISA for quantification of specific IgG antibodies with a lysate of treponema pallidum as antigen.  1, record 14, English, - avidity

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Capacité d'un antisérum de se lier aux antigènes et d'exercer certaines fonctions biologiques consécutives à sa liaison avec ces antigènes.  1, record 14, French, - avidit%C3%A9

Record 14,  Textual support,  Spanish