TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

The U. S. [United States] Pharmacopoeia(USP) has three general specifications for water quality that are applicable to medical and pharmaceutical uses, namely ’USP Water for Injection’(WFI), ’USP Purified Water’(PW) and ’Drinking Water. ’… WFI requires the removal of a subgroup of endotoxins that are lipopolysaccharides(material that makes up the cell wall of Gram-negative bacteria and can cause an immune system response and fever termed "pyrogens"). … Thus, pyrogen-free water is a critical aspect of parenteral drug manufacturing.  1, record 1, English, - pyrogen%2Dfree%20water

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Eau exempte de substances pyrogènes.  2, record 1, French, - eau%20apyrog%C3%A8ne

Record number: 1, Textual support number: 1 CONT

L'eau stérile est une eau où il y a absence totale de germes. L'eau apyrogène est une eau qui ne provoque pas de fièvre après injection.  1, record 1, French, - eau%20apyrog%C3%A8ne

Record number: 1, Textual support number: 1 OBS

pyrogène : qui engendre de la fièvre.  3, record 1, French, - eau%20apyrog%C3%A8ne

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 CONT

Técnicas de purificación. [...] Ultrafiltración: retiene coloides, microorganismos y pirógenos, se utiliza habitualmente para la obtención de agua apirógena y libre de nucleasas.  2, record 1, Spanish, - agua%20apir%C3%B3gena

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

A typical pharmaceutical process consists of mainstream processing steps as well as steps associated with support system such as Cleaning in place(CIP), Sterilization in place(SIP), Water for injection(WFI), raw material preparation, reworking of material, analyst of material in laboratories, etc.  2, record 2, English, - pharmaceutical%20process

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

[...] l'invention d'un procédé pharmaceutique repose sur l'utilisation de substances chimiques données ayant des effets particuliers sur l'organisme. La combinaison des mêmes substances chimiques dans les mêmes conditions conduira automatiquement au même procédé.  2, record 2, French, - proc%C3%A9d%C3%A9%20pharmaceutique

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

Not producing fever.  2, record 3, English, - apyrogenic

Record number: 3, Textual support number: 1 CONT

From research to production, water is as vital a raw material for the pharmaceutical industry as it is to life itself. Water is an ideal solvent for many drugs, vaccines and lotions and is therefore a major ingredient in many medicines.... Water for injection(WFI), for example, demands the highest specification and needs to be apyrogenic and bacteria free.  1, record 3, English, - apyrogenic

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Si la pollinose est en général apyrogène (ne s'accompagnant pas de fièvre), certains se plaignent de se sentir fébriles et fatigués pendant cette période (à rapprocher de l'appellation anglophone «hay fever» fièvre des foins).  1, record 3, French, - apyrog%C3%A8ne

Record 3,  Textual support,  Spanish