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YEAST ARTIFICIAL CHROMOSOME [4 records]
Record 1 - internal organization data 2010-08-11
Record 1, English
Record 1, Subject field(s)
- Biotechnology
Record 1, Main entry term, English
- reverse band
1, record 1, English, reverse%20band
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- R band 2, record 1, English, R%20band
proposal
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The molar fractions of guanine plus cytosine(GC) in DNA were determined for 36 yeast artificial chromosomes(YACs) which almost completely cover human chromosome band Xq28, a terminal reverse band, corresponding to about 8 Mb of DNA. This allowed the construction of the most complete compositional map to date of a chromosomal band... 1, record 1, English, - reverse%20band
Record number: 1, Textual support number: 1 OBS
Proceedings of the National Academy of Sciences, Volume 93, Number 03; Pages: 1298-1302 2, record 1, English, - reverse%20band
Record 1, French
Record 1, Domaine(s)
- Biotechnologie
Record 1, Main entry term, French
- bande réverse
1, record 1, French, bande%20r%C3%A9verse
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- bande R 1, record 1, French, bande%20R
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les chromosomes métaphasiques humains présentent divers types de bandes selon le traitement auquel ils sont soumis (colorants, température, enzymes protéolytiques ou DNases). Les bandes G(iemsa) positives représentent environ 50 % des bandes chromosomiques, l'autre moitié étant constituée de bandes G(iemsa) négatives. Ces dernières ne sont que les bandes R(everse) obtenues par dénaturation thermique. 1, record 1, French, - bande%20r%C3%A9verse
Record number: 1, Textual support number: 1 OBS
Elles sont obtenues par dénaturation thermique en solution saline, spécifiques des régions riches en guanine et en cytosine ainsi qu'en gènes de synthèse précoces. 2, record 1, French, - bande%20r%C3%A9verse
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2010-06-22
Record 2, English
Record 2, Subject field(s)
- Biotechnology
Record 2, Main entry term, English
- large-capacity bacterial vector
1, record 2, English, large%2Dcapacity%20bacterial%20vector
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
A more detailed map of a large YAC [yeast artificial chromosome] insert can be produced by subcloning, a process in which fragments of the original insert are cloned into smaller-insert vectors. Because some YAC regions are unstable, large-capacity bacterial vectors(i. e. those that accommodate large inserts) are also being developed. 1, record 2, English, - large%2Dcapacity%20bacterial%20vector
Record 2, French
Record 2, Domaine(s)
- Biotechnologie
Record 2, Main entry term, French
- vecteur bactérien de grande capacité
1, record 2, French, vecteur%20bact%C3%A9rien%20de%20grande%20capacit%C3%A9
proposal, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2010-04-12
Record 3, English
Record 3, Subject field(s)
- Genetics
Record 3, Main entry term, English
- mammalian artificial chromosome
1, record 3, English, mammalian%20artificial%20chromosome
correct
Record 3, Abbreviations, English
- MAC 2, record 3, English, MAC
correct
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
We therefore propose to undertake the identification, assembly and test of the structural elements necessary for the proper function and stability of a mammalian artificial chromosome(MAC). To achieve this goal, we will create a chimaera between an existing Yeast Artificial Chromosome(YAC) and selected human and other mammalian genomic sequences. The stability and autonomous replication of the MAC in human cells will be evaluated by a variety of assays, both before and after the addition of candidate origins, telomeres and centromeres. 2, record 3, English, - mammalian%20artificial%20chromosome
Record 3, French
Record 3, Domaine(s)
- Génétique
Record 3, Main entry term, French
- chromosome mammifère artificiel
1, record 3, French, chromosome%20mammif%C3%A8re%20artificiel
correct, masculine noun
Record 3, Abbreviations, French
- MAC 2, record 3, French, MAC
correct, masculine noun
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
C'est ainsi qu'est né le concept de minichromosomes ou MAC (mammalian artificial chromosomes). Ceux-ci pourraient maintenir de grands morceaux d'ADN parallèlement aux chromosomes de la cellule sans risque d'intégration ou de recombinaison avec des virus et sans induire de réponse immunitaire. 3, record 3, French, - chromosome%20mammif%C3%A8re%20artificiel
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2007-08-08
Record 4, English
Record 4, Subject field(s)
- Genetics
Record 4, Main entry term, English
- yeast artificial chromosome
1, record 4, English, yeast%20artificial%20chromosome
correct
Record 4, Abbreviations, English
- YAC 2, record 4, English, YAC
correct
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
A map of human chromosome 3 which integrates both physical and genetic data has been developed from the fusion of two large collections of markers and corresponding yeast artificial chromosome(YAC) clones. 3, record 4, English, - yeast%20artificial%20chromosome
Record 4, French
Record 4, Domaine(s)
- Génétique
Record 4, Main entry term, French
- chromosome artificiel de levure
1, record 4, French, chromosome%20artificiel%20de%20levure
correct, masculine noun
Record 4, Abbreviations, French
- YAC 2, record 4, French, YAC
correct, masculine noun
Record 4, Synonyms, French
- chromosome de levure modifié 3, record 4, French, chromosome%20de%20levure%20modifi%C3%A9
masculine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Clonage de grands fragments d'ADN sous forme de chromosomes artificiels de levure (YAC, Yeast Artificial Chromosomes). Le principe de ce système consiste à munir de grands fragments d'ADN exogène (humain par exemple) de tous les éléments qui permettent leur propagation dans la levure [...]. Ces constructions sont alors répliquées par la levure comme s'il s'agissait d'un chromosome endogène. On peut ainsi construire des banques dans lesquelles chaque clone de levure contient un segment d'ADN humain de grande taille propagé sous forme de chromosome artificiel. 4, record 4, French, - chromosome%20artificiel%20de%20levure
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Genética
Record 4, Main entry term, Spanish
- cromosoma artificial de levadura
1, record 4, Spanish, cromosoma%20artificial%20de%20levadura
correct, masculine noun
Record 4, Abbreviations, Spanish
- YAC 1, record 4, Spanish, YAC
correct, masculine noun
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record number: 4, Textual support number: 1 DEF
Cromosoma artificial que se emplea como vector de clonación de grandes fragmentos de ADN de otras especies en el genoma de la levadura. 1, record 4, Spanish, - cromosoma%20artificial%20de%20levadura
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