TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

ACCUMULATION DISEASE [14 records]

Record 1 2024-10-10

English

Subject field(s)
  • Human Diseases - Various
  • Liver and Biliary Ducts
CONT

Metabolic dysfunction-associated steatotic liver disease(MASLD) is one of the most common causes of chronic liver disease in the developed world. It is a spectrum of disease, ranging from hepatic fat accumulation without inflammation to steatohepatitis, fibrosis, cirrhosis, and end-stage liver disease. MASLD is considered the hepatic manifestation of metabolic syndrome and is associated with obesity, dyslipidemia, and type 2 diabetes mellitus. The diagnosis of MASLD is based on [the] exclusion of other etiologies of steatotic liver disease, such as alcohol use, and supportive laboratory tests and imaging.

Key term(s)
  • metabolic dysfunction associated steatotic liver disease

French

Domaine(s)
  • Maladies humaines diverses
  • Foie et voies biliaires
CONT

La maladie du foie associée à un dysfonctionnement métabolique (MASLD [metabolic dysfunction-associated liver disease]) comprend une infiltration graisseuse simple (une maladie bénigne appelée maladie stéatosique hépatique) et la stéatohépatite associée à un dysfonctionnement métabolique (MASH [metabolic dysfunction-associated steatohepatitis]), une variante moins fréquente, mais plus importante.

Spanish

Save record 1

Record 2 2020-11-10

English

Subject field(s)
  • Symptoms (Medicine)
  • Hygiene and Health
  • Dietetics
DEF

... a predominant accumulation of fat in the truncal area, which includes subcutaneous and visceral adipose tissue compartments[, and] associated with high risk for [cardiovascular disease and type 2 diabetes. ]

Key term(s)
  • upper body obesity

French

Domaine(s)
  • Symptômes (Médecine)
  • Hygiène et santé
  • Diététique
CONT

Grâce à la mesure de périmètre abdominal avec un simple mètre ruban, l'obésité abdominale est définie dès lors que cette mesure est supérieure à : 102 cm chez l'homme, 88 cm chez la femme (en dehors de la grossesse).

Spanish

Campo(s) temático(s)
  • Síntomas (Medicina)
  • Higiene y Salud
  • Dietética
Save record 2

Record 3 2019-12-05

English

Subject field(s)
  • Human Diseases - Various
  • Genetics
  • Nervous System
CONT

Alexander disease is a rare leukodystrophy characterized by Rosenthal fiber accumulation in astrocytes, secondary to glial fibrillary acidic protein(GFAP) gene mutations.

OBS

Based on the age of onset and [the] type of symptoms present, ALX [can be] classified into three forms: infantile, juvenile, and adult.

French

Domaine(s)
  • Maladies humaines diverses
  • Génétique
  • Système nerveux
CONT

La maladie d'Alexander est une pathologie rare, liée à une mutation du gène GFAP (glial fibrillary acidic protein [protéine acide gliofibrillaire]). Dans sa forme typique, il s'agit d'une leucodystrophie infantile rapidement fatale, caractérisée par l'accumulation de fibres de Rosenthal.

Spanish

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Record 4 2019-11-21

English

Subject field(s)
  • Human Diseases - Various
  • Genetics
CONT

Mucopolysaccharidosis type II(MPS II; Hunter syndrome) is a rare X-linked recessive disease caused by deficiency of the lysosomal enzyme iduronate-2-sulphatase, leading to progressive accumulation of glycosaminoglycans in nearly all cell types, tissues and organs. Clinical manifestations include severe airway obstruction, skeletal deformities, cardiomyopathy and, in most patients, neurological decline.

Key term(s)
  • MPSII
  • mucopolysaccharidosis type 2
  • mucopolysaccharidosis 2
  • MPS2

French

Domaine(s)
  • Maladies humaines diverses
  • Génétique
CONT

La mucopolysaccharidose de type II est une maladie évolutive, progressive [et] multisystémique. […] Il s'agit d'une maladie génétique transmise sur le mode récessif lié au chromosome X.

Key term(s)
  • MPSII
  • mucopolysaccharidose de type 2
  • MPS2

Spanish

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Record 5 2018-03-09

English

Subject field(s)
  • Bacterial Diseases
  • Microbiology and Parasitology
CONT

Mycobacterial disease is one type infection caused by germs accumulation. These mycobacterial diseases include tuberculosis, leprosy, Mycobacteria ulcer and Mycobacterium para tuberculosis.

French

Domaine(s)
  • Maladies bactériennes
  • Microbiologie et parasitologie

Spanish

Campo(s) temático(s)
  • Enfermedades bacterianas
  • Microbiología y parasitología
Save record 5

Record 6 2012-02-03

English

Subject field(s)
  • The Lungs
  • Occupational Health and Safety
  • Mining Dangers and Mine Safety
DEF

An occupational disease of coal workers resulting from deposition of coal dust in the lungs.

OBS

Black lung disease is the common name for coal workers’ pneumoconiosis (CWP) or anthracosis, a lung disease of older workers in the coal industry, caused by inhalation, over many years, of small amounts of coal dust.

OBS

anthracosis : A histological term describing the accumulation of black pigment in lung tissue or in other organs. In the lung the accumulation often appears as macular lesions, usually in a centrilobular location, along the walls of bronchioles, but also along interlobular septa or in the subpleural space. This pigment is mainly composed of carbonaceous material and may originate from cigarette smoke(or other smoked drugs, such as crack cocaine), atmospheric pollution, residential exposure to wood(or biomass) smoke or occupational exposure to carbon-containing dusts, such as diesel exhaust, soot, fly ash, carbon black, graphite and coal. Thus a more or less marked degree of anthracosis may be found in nonsmoking urban residents from heavily polluted areas or in inhabitants(often females) of poor countries with a cold climate(so-called ’hut lung’). Anthracosis is only rarely associated with overt pulmonary disease, except after prolonged, heavy, usually occupational exposure, when the condition is preferably labelled as a pneumoconiosis, e. g. graphite pneumoconiosis(graphitosis) or coal workers pneumoconiosis. The latter pneumoconiosis is often called anthracosilicosis(particularly in continental Europe), because this pneumoconiosis has been considered to be caused predominantly by the silica content of coal dust. While this may be true in many instances, the use of anthracosilicosis to indicate coal worker's pneumoconiosis is probably not entirely appropriate, because the pathology of coal workers pneumoconiosis is different from that of silicosis.

OBS

black phthisis; colliers’ phtisis: obsolete.

OBS

bituminosis; melanedema; miners’ asthma: obsolete and incorrect.

French

Domaine(s)
  • Poumons
  • Santé et sécurité au travail
  • Exploitation minière (dangers et sécurité)
DEF

Pneumoconiose due à une infiltration massive de poussières de charbon chez des individus exposés professionnellement à une atmosphère très polluée.

OBS

L'existence d'anthracose pure est controversée. Il semble qu'il s'agisse plus souvent d'une anthracosilicose, la silice entrant en plus ou moins grande quantité dans la composition de la poussière de charbon.

OBS

Comparer avec «anthracose» et avec «anthracosilicose».

Spanish

Campo(s) temático(s)
  • Pulmones
  • Salud y seguridad en el trabajo
  • Explotación minera (peligros y seguridad)
OBS

neumoconiosis: es un proceso respiratorio crónico, de marcha tórpida, que consiste en una fibrosis pulmonar linfoectásica consecutiva a la inhalación de diversas clases de polvos, aspirados durante años en el ejercicio de distintas profesiones (molineros, mineros, picapedreros, etc.)

OBS

La primera [neumoconiosis producida por polvos inorgánicos] conocida fue la antracosis, tan frecuente entre los mineros de carbón. Hoy se sabe que no es producida por el polvo de carbón, sino por el cuarzo mezclado con él, o sea que en realidad es una silicosis

OBS

artículo 153. 12. antracosis. Mineros (de las minas de carbón), carboneros, herreros, soldadores, forjadores, fundidores, fogoneros, deshollinadores y demás trabajadores expuestos a inhalación de polvos de carbón de hulla, grafito y antracita.

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Record 7 2011-08-10

English

Subject field(s)
  • Animal Diseases
  • Pig Raising
DEF

An infectious viral disease of swine that is easily transmitted through direct contact to susceptible pigs and vertically to foetuses [...] it is characterised by reproductive failure of sows and respiratory distress of piglets and growing pigs. The characteristics of the reproductive failure are infertility, late foetal mummification, abortions, agalactia, stillbirths, and weak piglets that usually die shortly after birth due to respiratory disease and secondary bacterial infections [...]

CONT

This article briefly describes the PRRS(porcine reproductive and respiratory syndrome), which arose in the winter of 1990 in Germany and other European countries... The clinical picture of this new disease, which led to important economical losses is dominated by 1. an increased rate of reduced length of pregnancy with late abortion before day 110 or an increased length of pregnancy; 2. an increase in stillborn piglets; 3. a larger scale of preweaning mortality combined with a higher frequency of secondary infections... Pathological findings in piglets are subcutaneous edema, accumulation of fluids in the body cavities and sometimes interstitial pneumonia is observed... At present a non-classified virus, isolated by Dutch researchers is proposed to be the causative agent and named Lelystad virus.

French

Domaine(s)
  • Maladies des animaux
  • Élevage des porcs
OBS

Équivalent tiré d'une liste de descripteurs français d'un article de la base de données PASCAL.

Spanish

Campo(s) temático(s)
  • Enfermedades de los animales
  • Cría de ganado porcino
DEF

Enfermedad viral de gran impacto económico dentro de la porcicultura; se caracteriza por un aumento en las repeticiones del celo en las hembras, abortos tardíos, disminución de la fertilidad, incremento en el número de cerdos momificados, nacidos muertos y débiles. Aumenta el porcentaje de mortalidad en lactancia y al destete; 2 a 5 semanas posteriores aparecen los abortos, mortinatos, momias y disminución en el tamaño de las camadas. El período de incubación es de 4 a 7 días en que los cerdos manifiestan anorexia y fiebre.

OBS

PRRS y SIRS, por sus siglas en inglés.

Save record 7

Record 8 2011-02-18

English

Subject field(s)
  • Endocrine System and Metabolism
DEF

A storage disease resulting from glycocerebroside accumulation in macrophages due to a genetic deficiency of glucocerebrosidase.

CONT

[Gaucher’s disease] may occur in adults but occurs most severely in infants, in whom cerebroside also accumulates in neurons; marked by hepatosplenomegaly, lymphadenopathy, and bone destruction by characteristic cells containing cytoplasmic tubules; autosomal recessive inheritance.

French

Domaine(s)
  • Systèmes endocrinien et métabolique
DEF

Maladie héréditaire du métabolisme des sphingolipides, et génétique de transmission autosomique récessive, due au déficit en b-glucosidase acide. Elle est classée parmi les maladies lysosomales.

OBS

Le déficit enzymatique conduit à l'accumulation pathologique du substrat (glucocérébroside) dans les lysosomes. Cette surcharge métabolique est responsable d'une maladie polyviscérale avec hépatosplénomégalie, infiltration de la moelle osseuse avec anémie et thrombopénie, et atteinte osseuse. L'atteinte neurologique est plus rare, définissant les maladies de Gaucher de type 2 et 3.

Spanish

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Record 9 2004-11-04

English

Subject field(s)
  • Liver and Biliary Ducts
DEF

The orange-yellow pigment of bile, formed principally by the breakdown of hemoglobin in red blood cells after termination of their normal lifespan.

OBS

Water-insoluble, unconjugated bilirubin normally travels in the bloodstream to the liver, where it is converted to a water-soluble, conjugated form and excreted into the bile. In a healthy person about 250 mg of bilirubin are produced daily. The majority of bilirubin is excreted in the stool. The characteristic yellow pallor of jaundice is caused by the accumulation of bilirubin in the blood and in the tissues of the skin. Testing for bilirubin in the blood provides information for diagnosis and evaluation of liver disease, biliary obstruction, and hemolytic anemia. Normal levels of total bilirubin are 0. 1 to 1. 0 mg/dl or 5. 1-17. 0 mmol/L.

Key term(s)
  • bilifulvine
  • biliphéine

French

Domaine(s)
  • Foie et voies biliaires
DEF

Pigment jaune-brun provenant de la dégradation de l'hémoglobine (et de quelques autres pigments respiratoires) et constituant le principal colorant de la bile.

OBS

La bilirubine libre, insoluble dans l'eau, est surtout produite dans la rate et la moelle osseuse et transportée jusqu'au foie par l'albumine du foie. La bilirubine conjugée, soluble dans l'eau, est obtenue après transformation chimique dans le foie et excrétée dans la bile.

Spanish

Campo(s) temático(s)
  • Hígado y conductos biliares
OBS

La bilirrubina es liberada por los glóbulos rojos viejos o dañados. Pequeñas cantidades de bilirrubina circulan normalmente en el torrente sanguíneo, hasta que llega al hígado donde se metaboliza para eliminarse posteriormente por los intestinos. Su aumento en la sangre produce la coloración amarilla de la piel llamada ictericia y puede ser indicación de enfermedad hepática o destrucción acelerada y masiva de glóbulos rojos.

Save record 9

Record 10 2004-01-08

English

Subject field(s)
  • Animal Diseases
  • Poultry Production
DEF

A slow-spreading disease of fowl and turkeys caused by the avian poxvirus and characterized by pox lesions on the skin of the head, and on the neck in turkeys. Involvement of eyelids causes lacrimation and accumulation of caseous material in the conjunctival sac. Lesions may also be present in the mouth oesophagus and upper respiratory tract. Transmitted by mosquitos or by contact.

OBS

Although the same disease exists for both humans and fowl (the disease being transmitted to man by birds), two distinct records were made for "fowlpox" because of the different synonyms and equivalents.

French

Domaine(s)
  • Maladies des animaux
  • Élevage des volailles
CONT

La variole aviaire est provoquée par un virus filtrant épithéliotrope qui provoque le développement d'inclusions intracytoplasmiques, appelées corpuscules de Bollinger. [...] La maladie est caractérisée par des éruptions sur les régions du corps dépourvues de plumes et aussi par des fausses membranes diphtéroïdes dans la cavité buccale. Selon le siège et le type des lésions, on distingue une forme cutanée et une forme muqueuse. Dans certains cas, elles peuvent se présenter simultanément.

OBS

À noter que le VIVET, 1984 classe la diphtérie aviaire et l'épithélioma contagieux comme des formes distinctes de la variole aviaire.

OBS

Bien qu'il s'agisse de la même maladie, "fowlpox" ne porte pas le même nom en français chez l'homme que chez les autres animaux.

Spanish

Campo(s) temático(s)
  • Enfermedades de los animales
  • Cría de aves
DEF

Enfermedad causada por un virus que se caracteriza por su diseminación lenta. Este mal presenta lesiones cutáneas y del tipo diftérico en las mucosas respiratorias y digestivas de las aves. Con mayor frecuencia se observa en pollos y pavos, pudiendo también afectar a canarios, palomas y otros.

OBS

viruela aviar: término proveniente del Código Zoosanitario Internacional, 2002.

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Record 11 2004-01-07

English

Subject field(s)
  • Hygiene and Health
CONT

There is a difference between aging and the accumulation of disease over time.

French

Domaine(s)
  • Hygiène et santé
CONT

Il ne faut pas confondre vieillissement et aggravation progressive des problèmes de santé.

Spanish

Save record 11

Record 12 2003-12-10

English

Subject field(s)
  • Effects of Pollution
  • The Lungs
DEF

A usually asymptomatic form of pneumoconiosis caused by deposition of coal dust in the lungs [which] is present in most urban dwellers.

OBS

anthracosis : A histological term describing the accumulation of black pigment in lung tissue or in other organs. In the lung the accumulation often appears as macular lesions, usually in a centrilobular location, along the walls of bronchioles, but also along interlobular septa or in the subpleural space. This pigment is mainly composed of carbonaceous material and may originate from cigarette smoke(or other smoked drugs, such as crack cocaine), atmospheric pollution, residential exposure to wood(or biomass) smoke or occupational exposure to carbon-containing dusts, such as diesel exhaust, soot, fly ash, carbon black, graphite and coal. Thus a more or less marked degree of anthracosis may be found in nonsmoking urban residents from heavily polluted areas or in inhabitants(often females) of poor countries with a cold climate(so-called ’hut lung’). Anthracosis is only rarely associated with overt pulmonary disease, except after prolonged, heavy, usually occupational exposure, when the condition is preferably labelled as a pneumoconiosis, e. g. graphite pneumoconiosis(graphitosis) or coal workers pneumoconiosis. The latter pneumoconiosis is often called anthracosilicosis(particularly in continental Europe), because this pneumoconiosis has been considered to be caused predominantly by the silica content of coal dust. While this may be true in many instances, the use of anthracosilicosis to indicate coal worker's pneumoconiosis is probably not entirely appropriate, because the pathology of coal workers pneumoconiosis is different from that of silicosis.

OBS

Compare with "pneumoconiosis of coal workers" and "anthracosilicosis."

French

Domaine(s)
  • Effets de la pollution
  • Poumons
DEF

Noircissement du poumon dû à l'inhalation de poussières de charbon.

OBS

Le terme «anthracose» est parfois employé pour désigner la «pneumoconiose des houilleurs». Voir aussi cette fiche, de même que «anthracosilicose».

Spanish

Campo(s) temático(s)
  • Efectos de la polución
  • Pulmones
DEF

Variedad de neumoconiosis producida por la inhalación de polvo de carbón.

Save record 12

Record 13 2003-06-23

English

Subject field(s)
  • Animal Diseases
DEF

(so called from the accumulation of fluid in the pericardium) : a serious febrile disease of sheep, goats, and cattle in southern Africa caused by a rickettsial micro-organism(Cowdria ruminantium) transmitted by a tick...

OBS

veld sickness: South Africa.

OBS

bush sickness: Africa.

Key term(s)
  • Boschziekte
  • inapunga
  • heartwater disease

French

Domaine(s)
  • Maladies des animaux
DEF

Maladie infectieuse, non contagieuse, des ruminants, due à Rickettsia ruminantium, en Afrique et à Madagascar. [...] La lésion la plus caractéristique est une hydropisie des séreuses notamment du péricarde. Les tiques sont les vecteurs de la rickettsie.

Spanish

Campo(s) temático(s)
  • Enfermedades de los animales
Save record 13

Record 14 2000-03-02

English

Subject field(s)
  • Endocrine System and Metabolism
CONT

Patients with liver disease may show signs of B1 deficiency, possibly because of deficient synthesis of lipoic acid. In vitro, thiamine deficiency produces accumulation of pyruvate and lactate, reduction of acetate, citrate and alpha-keto-glutarate and reduced acetylcholine synthesis. Any of these metabolic changes could be involved in dysfunction.

French

Domaine(s)
  • Systèmes endocrinien et métabolique
DEF

Déséquilibre métabolique caractérisé par l'incapacité de l'organisme à synthétiser une substance indispensable à son fonctionnement.

Spanish

Campo(s) temático(s)
  • Sistemas endocrino y metabólico
Save record 14

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