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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

An early B-lymphoid type cell that is recognised by immunofluorescence as a u-positive, L-chain-negative bone marrow cell.  3, record 1, English, - pre%2DB%20lymphocyte

Record number: 1, Textual support number: 1 CONT

Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in Vpre-B1-deficient mice.  2, record 1, English, - pre%2DB%20lymphocyte

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

On individualise quatre stades qui conduisent le précurseur B au lymphocyte B mature : successivement il passe par les stades de lymphocyte pro-B précoce, lymphocyte pro-B tardif, puis lymphocyte pré-B et enfin lymphocyte B immature. Cette progression se fait au contact des cellules stromales qui fournissent les informations nécessaires à cette progression, d'abord par contact cellulaire direct aux stades précoces, puis par l'intermédiaire de médiateurs solubles aux stades tardifs.  1, record 1, French, - lymphocyte%20pr%C3%A9%2DB

Record number: 1, Textual support number: 2 CONT

La prolifération et la différentiation des cellules pro-B en cellules pré-B requièrent le microenvironnement produit par les cellules stromales de la moelle osseuse. Les cellules stromales jouent deux rôles importants : elles interagissent directement avec les cellules pro-B et pré-B et elles sécrètent des cytokines variées, en particulier IL7.  2, record 1, French, - lymphocyte%20pr%C3%A9%2DB

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 CONT

La molécula CD20 [...] es una proteína transmembrana cuya presencia queda restringida a las células B en los estadios de maduración desde la célula preB hasta las células B memoria.  1, record 1, Spanish, - c%C3%A9lula%20preB

Record number: 1, Textual support number: 1 OBS

pre-: La Fundación del Español Urgente (Fundéu BBVA), con el asesoramiento de la Real Academia Española, indica que el prefijo pre-, igual que todos los prefijos, se escribe unido a la palabra, sin guion ni espacio: preelectoral, prehispánico, preindustrial [...]  3, record 1, Spanish, - c%C3%A9lula%20preB

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

A lymphocyte that develops in the bone marrow and lacks the characteristic surface markers of the B and T lymphocytes.  5, record 2, English, - null%20cell

Record number: 2, Textual support number: 1 OBS

Kinds of null cells are killer cells and natural killer cells.  6, record 2, English, - null%20cell

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Cellule lymphoïde ne présentant aucun marqueur des cellules B et T.  5, record 2, French, - cellule%20nulle

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

The clonal selection theory is based on the proposition that during development each lymphocyte becomes committed to react with a particular antigen before ever being exposed to it. A cell expresses this commitment in the form of surface receptor proteins that specifically fit the antigen. The binding of antigen to the receptors activates the cell, causing it both to multiply and mature. Thus a foreign antigen selectively stimulates those cells that bear complementary antigen-specific receptors and are thus already committed to respond to it. This is what makes immune responses antigen-specific. The term "clonal" in clonal selection derives from the postulate that the immune system is composed of millions of different families, or clones, of cells, each consisting of T or B lymphocytes descended from a common ancestor. Since each ancestral cell is already committed to make one particular antigen-specific receptor protein, all cells in a clone have the same antigen specificity.  1, record 3, English, - clonal%20selection

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Selon la théorie de la sélection clonale, les lymphocytes [sont] groupés en clones, un clone étant un ensemble de cellules identiques, descendantes d'une même cellule initiale, et exprimant les mêmes potentialités génétiques. Ainsi, chaque clone de lymphocyte B comporte-t-il un ensemble de cellules identiques, chacune synthétisant une espèce d'immunoglobuline, et une seule. Ce clone est sélectivement stimulé par l'antigène reconnu spécifiquement par l'immunoglobuline qu'il exprime.  1, record 3, French, - s%C3%A9lection%20clonale

Record 3,  Textual support,  Spanish

Record number: 3, Textual support number: 1 DEF

Producción de una población de células plasmáticas productoras de un mismo anticuerpo en respuesta a la interacción entre un linfocito B que produce el anticuerpo específico y el antígeno fijado por dicho anticuerpo.  2, record 3, Spanish, - selecci%C3%B3n%20clonal

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

An antigen which does not require T lymphocyte participation to elicit an immune response in B lymphocytes. Animals lacking a thymus can respond to these antigens.  3, record 4, English, - thymus%2Dindependent%20antigen

Record number: 4, Textual support number: 2 DEF

An antigen that can trigger B cells to produce antibodies without the participation of T cells; most are polymers with a simple repeating pattern and are B cell mitogens; only IgM is produced and few memory cells are formed.  4, record 4, English, - thymus%2Dindependent%20antigen

Record number: 4, Textual support number: 1 CONT

T-independent antigens can directly stimulate B cells....  2, record 4, English, - thymus%2Dindependent%20antigen

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Antigène vis-à-vis duquel la production des anticorps (essentiellement IgM) ne nécessite pas la présence des cellules T. La production de ces anticorps n'est cependant pas strictement thymo-indépendante car elle peut être soumise à l'action régulatrice de cellules T suppressives et amplificatrices.  1, record 4, French, - antig%C3%A8ne%20thymo%2Dind%C3%A9pendant

Record number: 4, Textual support number: 1 CONT

Antigènes thymo-indépendants: Type 1 (T.I.-1) : lipopolysaccharides (LPS), flagelline polymérisée, polyvinylpyrrolidone; Type 2 (T.I.-2) : polysaccharides solubles (par ex. polysaccharides SIII polymères synthétiques de D-acides aminés. (J.-F. Bach, P. Lesavre, Op. cit. p. 43.  3, record 4, French, - antig%C3%A8ne%20thymo%2Dind%C3%A9pendant

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

Terminally differentiated cell of the B lymphocyte lineage that produces antibodies; an oval or round cell with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic "cartwheel" heterochromatin pattern.  1, record 5, English, - plasma%20cell

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Cellule lymphoïde de 10 à 15 [micromètres], à noyau excentré, à chromatine en mottes, à cytoplasme très basophile, riche en mitochondries et en ergastoplasme, qui synthétise et excrète les immunoglobulines.  1, record 5, French, - plasmocyte

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 DEF

Célula derivada de los linfocitos B, que ante la presencia de un estímulo, se replica rápidamente y empieza a producir anticuerpos.  3, record 5, Spanish, - plasmocito

Record number: 5, Textual support number: 1 OBS

Su presencia normalmente indica alguna patología.  1, record 5, Spanish, - plasmocito

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

A lymphoid stem cell from the bone marrow that migrates to, and becomes a mature antigen-specific cell in, the spleen and lymph nodes.  2, record 6, English, - B%20cell

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Les lymphocytes sont divisés en deux grandes catégories, les lymphocytes B et les lymphocytes T [...] Les lymphocytes B sont les seules cellules de l'organisme qui synthétisent des immunoglobulines ou anticorps.  2, record 6, French, - lymphocyte%20B

Record 6,  Textual support,  Spanish

Record number: 6, Textual support number: 1 DEF

Tipo de linfocito que se encuentra en la médula ósea humana. Son los precursores de las células plasmáticas productoras de anticuerpos.  3, record 6, Spanish, - linfocito%20B

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

Immunoglobulin present on the cell membrane, an important characteristic of a B lymphocyte.  1, record 7, English, - surface%20immunoglobulin

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

Les lymphocytes B utilisent leur immunoglobuline de surface (S-Ig), exposant son fragment Fab face à l'antigène et dont la spécificité antigénique est génétiquement déterminée.  1, record 7, French, - immunoglobuline%20de%20surface

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

The development of influenza virus-specific CD8+ cytotoxic T lymphocyte precursors(CTLp) is diminished in H-2b mice that are homozygous(-/-) for disruption of the H-2IA b gene. Virus clearance was not obviously delayed when compared with the congenic H-2IAb(+/+) controls, and evidence of CTL activity was apparent for inflammatory cells recovered from the respiratory tract in both cases. However, the virus-specific CTLp that are normally present in the regional lymph nodes and in the infected lung were evidently being consumed at the peak of the host response to give the terminally differentiated CTL effectors.  1, record 8, English, - cytotoxic%20T%20lymphocyte%20precursor

Record 8,  Textual support,  French

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

A key feature of lymphocyte function is that, unlike other body cells, small lymphocytes recirculate from blood to lymph. Recirculation is likely to be of great functional importance in allowing memory cells to be disseminated from a site of antigen stimulation to other parts of the body. Lymphocytes migrate from blood into lymph nodes... In the spleen the lymphocytes migrate from the anastomosing capillaries... B and T cells exit the lymph nodes by the efferent lymphatics and enter the lymph to be returned to the blood and continue to cycle.  1, record 9, English, - recirculation

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 CONT

Certains lymphocytes T suivent un parcours complexe, stéréotypé, qu'une fraction d'entre eux paraît emprunter de façon répétée, c'est la recirculation. Quittant les ganglions par le système lymphatique, ces lymphocytes T, en général à longue durée de vie, regagnent le canal thoracique qui les déverse dans le torrent circulatoire. Ils quittent alors le sang pour retourner dans les aires thymodépendantes du cortex profond en traversant les parois des veines post-capillaires.  1, record 9, French, - recirculation

Record 9,  Textual support,  Spanish