TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Desalkylgidazepam, or bromonordiazapam, is a newly emerging designer benzodiazepine that is structurally related to nordiazepam... It is the active metabolite of gidazepam, an anxiolytic prescribed in Ukraine and Russia, but is also being manufactured illicitly as a drug on its own.  3, record 1, English, - desalkylgidazepam

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 OBS

Le désalkylgidazépam est une benzodiazépine de synthèse dont la structure est semblable à celle du nordiazépam. Il s'agit du métabolite actif du gidazépam.  2, record 1, French, - d%C3%A9salkylgidaz%C3%A9pam

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

Any of a group of compounds having a common molecular structure and acting similarly as depressants in the central nervous system, their actions including antianxiety, sedative, hypnotic, amnestic, anticonvulsant, and muscle relaxing effects.  4, record 2, English, - benzodiazepine

Record number: 2, Textual support number: 1 CONT

Benzodiazepines (BZD) are drugs marketed since the 1960s that act on the central nervous system through GABA [gamma-aminobutyric acid] receptors.  5, record 2, English, - benzodiazepine

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Les benzodiazépines agissent, au niveau du système nerveux central, sur des récepteurs spécifiques étroitement liés aux récepteurs du GABA (acide gamma-aminobutyrique) et au canal du chlore.  4, record 2, French, - benzodiaz%C3%A9pine

Record number: 2, Textual support number: 1 OBS

[...] les réponses de l'organisme aux benzodiazépines correspondent à une diminution de l'activité neuronale : diminution de l'anxiété (effet anxiolytique), diminution de la vigilance (effet sédatif et hypnotique), diminution d'origine centrale du tonus musculaire (effet myorelaxant, anticonvulsivant et antiépileptogène). Chaque benzodiazépine induit l'ensemble de ces réponses, mais l'une ou l'autre peut être plus marquée.  5, record 2, French, - benzodiaz%C3%A9pine

Record 2,  Textual support,  Spanish

Record number: 2, Textual support number: 1 CONT

Las benzodiacepinas pertenecen al grupo de medicamentos llamados depresores del sistema nervioso central, (medicamentos que frenan el sistema nervioso). [...] Muchas de las benzodiacepinas se utilizan en el tratamiento de otras condiciones, también. Diazepam se utiliza para ayudar a relajar los músculos o aliviar los espasmos musculares.  2, record 2, Spanish, - benzodiacepina

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

A class of benzodiazepine drugs with an additional fused triazole ring.  3, record 3, English, - triazolobenzodiazepine

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Classe de médicaments dérivés des benzodiazépines caractérisés par la présence d'un cycle triazole additionnel fusionné.  3, record 3, French, - triazolobenzodiaz%C3%A9pine

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 OBS

Bretazenil is a partial agonist of benzodiazepine receptors that is not approved for medicinal use.  2, record 4, English, - bretazenil

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 OBS

Il s'agit d'un agoniste partiel des récepteurs des benzodiazépines qui n'est pas approuvé pour usage médical.  2, record 4, French, - br%C3%A9taz%C3%A9nil

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

Clonazepam is a benzodiazepine drug used for the acute treatment of panic disorder, epilepsy, and nonconvulsive status epilepticus. The drug also has many off-label indications, including restless leg syndrome, acute mania, insomnia, and tardive dyskinesia.  2, record 5, English, - clonazepam

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 OBS

Benzodiazépine agoniste, [...] anticonvulsivant, myorelaxant, anxiolytique et sédatif. [Il est] indiqué dans le traitement de l'épilepsie sous toutes ses formes.  2, record 5, French, - clonaz%C3%A9pam

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 OBS

Phenazepam is a benzodiazepine that is not approved for medicinal use in Canada.  2, record 6, English, - phenazepam

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 OBS

Il s'agit d'une benzodiazépine qui n'est pas approuvée pour usage médical au Canada.  2, record 6, French, - ph%C3%A9naz%C3%A9pam

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

Norfludiazepam is a BZD [benzodiazepine], structurally related to the internationally controlled substance diazepam... It is the active metabolite of flurazepam and fludiazepam and is used in the synthesis of midazolam...  3, record 7, English, - norfludiazepam

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

Le norfludiazépam [...] est une benzodiazépine de synthèse à longue demi-vie [...]  1, record 7, French, - norfludiaz%C3%A9pam

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

Etizolam is a thienodiazepine which is chemically related to [the] benzodiazepine(BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A [gamma-aminobutyric acid A] receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties.  2, record 8, English, - etizolam

Record number: 8, Textual support number: 1 OBS

Etizolam is not approved for medicinal use in Canada.  3, record 8, English, - etizolam

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

L'étizolam est une thiénodiazépine, qui est proche de la famille des benzodiazépines [...]  2, record 8, French, - %C3%A9tizolam

Record number: 8, Textual support number: 1 OBS

L'étizolam n'est pas approuvé pour usage médical au Canada.  3, record 8, French, - %C3%A9tizolam

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

Metizolam is classified as a novel benzodiazepine.... Metizolam is structurally similar to etizolam.  2, record 9, English, - metizolam

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 OBS

Cette benzodiazépine est structurellement similaire à l'étizolam [...]  1, record 9, French, - m%C3%A9tizolam

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 OBS

... a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative, and antidepressant properties.  2, record 10, English, - adinazolam

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 OBS

L'adinazolam est un dérivé d'une benzodiazépine qui possède des propriétés anxiolytiques, anticonvulsives, sédatives et antidépressives.  2, record 10, French, - adinazolam

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

Oxazepam is used to relieve symptoms of anxiety, including anxiety caused by depression, and the symptoms of alcohol withdrawal. This medicine may also be used to treat tension, agitation, and irritability in older patients. Oxazepam is a benzodiazepine.  2, record 11, English, - oxazepam

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 OBS

Psychotrope de la famille des benzodiazépines anxiolytiques.  2, record 11, French, - oxaz%C3%A9pam

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 CONT

Pyrazolam is structurally similar to alprazolam, with pyrazolam having a bromine atom on the benzene ring of the benzodiazepine nucleus instead of chlorine and a pyridine ring instead of a benzene ring on C-6 of the diazepine ring.  2, record 12, English, - pyrazolam

Record 12,  Textual support,  French

Record number: 12, Textual support number: 1 OBS

Le pyrazolam est une benzodiazépine de synthèse dont la structure est semblable à celle de l'alprazolam.  2, record 12, French, - pyrazolam

Record 12,  Textual support,  Spanish

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 CONT

Fluclotizolam differs from brotizolam and etizolam by the substituents at the thiophene and phenyl ring. Based on its similarity to these compounds, fluclotizolam is expected to have sedative hypnotic effects.  2, record 13, English, - fluclotizolam

Record number: 13, Textual support number: 1 OBS

Data suggest that this benzodiazepine may be 2-3 times more potent than etizolam.  3, record 13, English, - fluclotizolam

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 OBS

Les données suggèrent que cette benzodiazépine peut être 2 à 3 fois plus puissante que l'étizolam.  2, record 13, French, - fluclotizolam

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 CONT

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients. Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system(CNS) depressants, which are medicines that slow down the nervous system.  2, record 14, English, - alprazolam

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 OBS

Psychotrope de la famille des benzodiazépines anxiolytiques.  2, record 14, French, - alprazolam

Record 14,  Textual support,  Spanish

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 CONT

Temazepam is used to treat insomnia(trouble with sleeping). This medicine is for short-term(usually 7 to 10 days) use only. Temazepam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system(CNS) depressants, which are medicines that slow down the nervous system.  2, record 15, English, - temazepam

Record 15,  Textual support,  French

Record number: 15, Textual support number: 1 OBS

Psychotrope de la famille des benzodiazépines hypnotiques.  2, record 15, French, - t%C3%A9mazepam

Record 15,  Textual support,  Spanish

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 CONT

Nitrazepam is a benzodiazepine with hypnotic and anticonvulsant properties.  2, record 16, English, - nitrazepam

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 CONT

Le nitrazépam est une benzodiazépine dotée de propriétés hypnotiques et anticonvulsivantes.  2, record 16, French, - nitraz%C3%A9pam

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 CONT

... BIND describes a constellation of functionally limiting neurologic symptoms(both physical and psychological) that are the consequence of neuroadaptation and/or neurotoxicity resulting from benzodiazepine exposure.  2, record 17, English, - benzodiazepine%2Dinduced%20neurological%20dysfunction

Record 17,  Textual support,  French

Record 17,  Textual support,  Spanish

Record 18,  Textual support,  English

Record number: 18, Textual support number: 1 DEF

A benzodiazepine... structurally and pharmacologically related to diazepam that is used in the form of its hydrochloride especially as a tranquilizer and to treat the withdrawal symptoms of alcohol.  3, record 18, English, - chlordiazepoxide

Record number: 18, Textual support number: 1 OBS

7-chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide: The capital letters "N" and "H" must be italicized.  2, record 18, English, - chlordiazepoxide

Record number: 18, Textual support number: 2 OBS

Chemical formula: C₁₆H₁₄ClN₃O  4, record 18, English, - chlordiazepoxide

Record 18,  Textual support,  French

Record number: 18, Textual support number: 1 DEF

Anxiolytique administré per os dans les états d'anxiété et de tension nerveuse.  4, record 18, French, - chlordiaz%C3%A9poxide

Record number: 18, Textual support number: 1 OBS

chlordiazépoxide : dénomination commune internationale.  3, record 18, French, - chlordiaz%C3%A9poxide

Record number: 18, Textual support number: 2 OBS

4-oxyde de 7-chloro-N-méthyl-5-phényl-3H-1,4-benzodiazépin-2-amine : Les lettres majuscule «N» et «H» s'écrivent en italique.  2, record 18, French, - chlordiaz%C3%A9poxide

Record number: 18, Textual support number: 3 OBS

Formule chimique : C₁₆H₁₄ClN₃O  5, record 18, French, - chlordiaz%C3%A9poxide

Record 18,  Textual support,  Spanish

Record number: 18, Textual support number: 1 OBS

Fórmula química: C₁₆H₁₄ClN₃O  2, record 18, Spanish, - clordiazep%C3%B3xido

Record 19,  Textual support,  English

Record number: 19, Textual support number: 1 DEF

A benzodiazepine used as an antianxiety agent in the treatment of anxiety disorders and for short-term relief of anxiety symptoms, as a preoperative or preprocedural medication to relieve anxiety and tension, also as a skeletal muscle relaxant, anticonvulsant, antitremor agent, antipanic agent, and for treatment of symptoms of acute alcohol withdrawal...  2, record 19, English, - diazepam

Record number: 19, Textual support number: 1 OBS

Active ingredient commonly sold under the name Valium.  3, record 19, English, - diazepam

Record number: 19, Textual support number: 2 OBS

Chemical formula: C₁₆H₁₃ClN₂O  4, record 19, English, - diazepam

Record 19,  Textual support,  French

Record number: 19, Textual support number: 1 DEF

Dérivé chlorométhylphénylique de la benzodiazépine, utilisé comme anxiolytique, myorelaxant, sédatif et antiépileptique.  2, record 19, French, - diaz%C3%A9pam

Record number: 19, Textual support number: 1 OBS

Principe actif couramment commercialisé sous le nom de Valium.  3, record 19, French, - diaz%C3%A9pam

Record number: 19, Textual support number: 2 OBS

Formule chimique : C₁₆H₁₃ClN₂O  4, record 19, French, - diaz%C3%A9pam

Record 19,  Textual support,  Spanish

Record number: 19, Textual support number: 1 OBS

Fórmula química: C₁₆H₁₃ClN₂O  2, record 19, Spanish, - diazepam

Record 20,  Textual support,  English

Record number: 20, Textual support number: 1 DEF

A benzodiazepine antagonist, used as an antidote in the treatment of benzodiazepine overdose.  1, record 20, English, - flumazenil

Record number: 20, Textual support number: 1 OBS

Active ingredient sold under the name Anexat (Roche).  3, record 20, English, - flumazenil

Record number: 20, Textual support number: 2 OBS

Chemical formula: C₁₅H₁₄FN₃O₃  3, record 20, English, - flumazenil

Record 20,  Textual support,  French

Record number: 20, Textual support number: 1 CONT

Voies thérapeutiques. Combinaison des benzodiazépines à un antagoniste comme le flumazénil, pour éviter l'effet flash à hautes doses, sans réduire les effets sédatifs ou anxiolytiques, et éviter l'apparition de la dépendance.  1, record 20, French, - flumaz%C3%A9nil

Record number: 20, Textual support number: 1 OBS

Principe actif commercialisé sous le nom Anexat (Roche).  2, record 20, French, - flumaz%C3%A9nil

Record number: 20, Textual support number: 2 OBS

Formule chimique : C[indice15]H₁₄FN₃O₃  2, record 20, French, - flumaz%C3%A9nil

Record 20,  Textual support,  Spanish

Record 21,  Textual support,  English

Record number: 21, Textual support number: 1 OBS

A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.  2, record 21, English, - lorazepam

Record number: 21, Textual support number: 2 OBS

Chemical formula: C₁₆H₁₂Cl₂N₂O₂  3, record 21, English, - lorazepam

Record 21,  Textual support,  French

Record number: 21, Textual support number: 1 OBS

Formule chimique : C₁₆H₁₂Cl₂N₂O₂  3, record 21, French, - loraz%C3%A9pam

Record 21,  Textual support,  Spanish

Record 22,  Textual support,  English

Record number: 22, Textual support number: 1 CONT

Since absorption rates, volumes of distribution and elimination rates differ greatly among the benzodiazepine derivatives... Two half-lives can be described : the alpha half-life, the rate of decline in plasma concentrations due to the process of drug redistribution from the central to the peripheral compartment, and the beta half-life, the rate of decline due to the process of drug elimination due to metabolism.  1, record 22, English, - alpha%20half%2Dlife

Record 22,  Textual support,  French

Record number: 22, Textual support number: 1 CONT

Dexrazoxane chlorhydrate. [...] Demi-Vie. Après administration intraveineuse, la demi-vie d'élimination est biphasique : - la demi-vie alpha se situe entre 10 et 20 minutes, - la demi-vie bêta se situe entre 2 et 3 heures. Elle peut être allongée en cas d'insuffisance rénale.  1, record 22, French, - demi%2Dvie%20alpha

Record 22,  Textual support,  Spanish

Record 23,  Textual support,  English

Record number: 23, Textual support number: 1 CONT

Three major methods for the quantitative analysis of benzodiazepine in plasma or serum are used : a) high-performance liquid chromatography with UV detection at 246 mm; b) immunoenzymology by the EMIT method for a semiquantitative determination(metabolites also measured) of diazepam levels, completed by a chromatographic method; c) gas-liquid chromatography.  1, record 23, English, - immunoenzymology

Record 23,  Textual support,  French

Record 23,  Textual support,  Spanish

Record 24,  Textual support,  English

Record number: 24, Textual support number: 1 CONT

In instances where clients have developed a benzodiazepine dependence, withdrawal protocols are available to guide the physician. However, a detailed discussion on this topic is beyond the scope of this Drug Bulletin. Please contact your provincial or territorial addiction agency for further information.  1, record 24, English, - addiction%20agency

Record 24,  Textual support,  French

Record number: 24, Textual support number: 1 CONT

Dans les cas de dépendance aux benzodiazépines, les protocoles de sevrage existants peuvent servir de guide aux médecins. Par contre, un exposé détaillé de ce sujet dépasse la portée de ce bulletin. Pour plus de renseignements, veuillez contacter l'organisme de lutte contre la toxicomanie de votre province ou de votre territoire.  1, record 24, French, - organisme%20de%20lutte%20contre%20la%20toxicomanie

Record 24,  Textual support,  Spanish

Record 25,  Textual support,  English

Record number: 25, Textual support number: 1 CONT

Human endozepine, an 86 amino acid polypeptide, was originally isolated from human brain tissue as a putative ligand of the benzodiazepine receptor. Complete amino acid sequencing of the human and bovine proteins revealed significant homology with the partial sequence of diazepam binding inhibitor(DBI), a protein from rat brain. Both endozepine and DBI have been shown to elicit behavioral effects, suggesting that they function as pharmacologically-active ligands of the GABA.  2, record 25, English, - endozepine

Record 25,  Textual support,  French

Record number: 25, Textual support number: 1 CONT

Compte tenu de la présence potentielle du (DBI) [diazapam-binding inhibitor] et des peptides qui lui sont apparentés (habituellement désignés sous le nom d'endozépines), on s'attendait à ce que ces peptides suscitent un grand nombre d'études neurochimiques et comportementales, à l'instar des ligands endogènes des récepteurs des opiacés.  1, record 25, French, - endoz%C3%A9pine

Record 25,  Textual support,  Spanish

Record 26,  Textual support,  English

Record number: 26, Textual support number: 1 DEF

A form of CBT [cognitive behavior therapy] described by Butler et al. (1984) for the treatment of social phobia. This treatment includes such techniques as relaxation, distraction, and rational self-talk.  1, record 26, English, - anxiety%20management%20training

Record number: 26, Textual support number: 1 CONT

Short and long-term effectiveness of group anxiety management training... Cognitive therapy, analytic psychotherapy and anxiety management training for generalised anxiety disorder... The effects of anxiety management training on psychological variables and immune parameters in cancer patients... Anxiety management training as a strategy for enhancing computer user performance... The study aimed at evaluating the efficacy of complaints management training(CMT) compared to that of anxiety management training(AMT) in patients undergoing benzodiazepine withdrawal... anxiety management training was delivered at fortnightly intervals by registrars in psychiatry after a brief period of training.... [Source : PASCAL database].  2, record 26, English, - anxiety%20management%20training

Record 26,  Textual support,  French

Record number: 26, Textual support number: 1 OBS

«gestion de l'anxiété» : Source - base de données PASCAL. Nota : en psychologie, on utilise encore souvent les anglicismes «management comportemental» et «self-management comportemental».  1, record 26, French, - entra%C3%AEnement%20%C3%A0%20la%20gestion%20de%20l%27anxi%C3%A9t%C3%A9

Record number: 26, Textual support number: 1 CONT

L'objet de cette étude est d'apprécier les effets de la gestion de l'anxiété par la relaxation ou par une technique cognitive sur les performances de 80 jeunes adultes [...] en situation d'apprentissage sur ordinateur [...] Les sujets sont également soumis à 2 types de relation à l'ordinateur : interaction du style amical-interaction du style moins amical [...] Les résultats montrent qu'il existe des effets significatifs de l'application des 2 techniques de gestion de l'anxiété ainsi que du style d'interaction à l'ordinateur dans les performances réalisées dans l'usage de l'ordinateur [Source : base de données PASCAL].  1, record 26, French, - entra%C3%AEnement%20%C3%A0%20la%20gestion%20de%20l%27anxi%C3%A9t%C3%A9

Record 26,  Textual support,  Spanish

Record 27,  Textual support,  English

Record number: 27, Textual support number: 1 OBS

Health Services and Promotion Branch.  2, record 27, English, - Effects%20of%20tranquillization%20%3Abenzodiazepine%20use%20in%20Canada

Record 27,  Textual support,  French

Record number: 27, Textual support number: 1 OBS

Direction générale des services et de la promotion de la santé.  2, record 27, French, - Effets%20de%20l%27usage%20de%20tranquillisants%20%3A%20l%27usage%20des%20benzodiaz%C3%A9pines%20au%20Canada

Record 27,  Textual support,  Spanish

Record 28,  Textual support,  English

Record number: 28, Textual support number: 1 CONT

Addiction potential of benzodiazepines and non-benzodiazepine anxiolytics.(In Advances in alcohol & substance abuse, 1990, 9(1-2) 103-128, cited in PASCAL data base.)  2, record 28, English, - non%20benzodiazepine

Record 28,  Textual support,  French

Record number: 28, Textual support number: 1 CONT

Posologies et caractéristiques pharmacocinétiques des hypnotiques non barbituriques et non benzodiazépines.  1, record 28, French, - non%20benzodiaz%C3%A9pine

Record number: 28, Textual support number: 2 CONT

Anxiolytique non sédatif d'efficacité comparable à celle des benzodiazépines, non apparenté aux benzodiazépines, aux carbamates ou aux neuroleptiques, dépourvu d'effets sédatifs, myorelaxants ou anticonvulsivants [...]  2, record 28, French, - non%20benzodiaz%C3%A9pine

Record 28,  Textual support,  Spanish