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CHROMOGRANIN B [1 record]

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Record 1 1999-03-05

English

Subject field(s)
  • Morphology and General Physiology
  • Cytology
CONT

Chromogranin B(secretogranin I or Scg-1) is a tyrosine-sulfated secretory protein found in a wide variety of peptidergic endocrine cells. Benedum et al.(1987) isolated a 2. 5-kb cDNA clone from a cDNA library of human pheochromocytoma. Chromogranin B is a 657 amino acid long polypeptide of 76 kilodaltons and is preceded by a cleaved end-terminal signal peptide of 20 residues. Chromogranin B was assigned to chromosome 20 by Craig et al.(1986). Craig et al.(1987) showed by in situ hybridization that the CHGB locus is on 20pter-p12. Jenkins et al.(1991) mapped the murine gene, symbolized Scg-1, to chromosome 2 by in situ hybridization and by interspecific backcross analysis.

French

Domaine(s)
  • Morphologie et physiologie générale
  • Cytologie
CONT

Le peptide correspondant à la séquence C-terminale de la chromogranine B a une activité lytique sélective contre la bactérie Micrococcus luteus à des concentrations infimes [...]

Spanish

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