TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

EPIDERMAL NECROLYSIS [5 records]

Record 1 2018-06-05

English

Subject field(s)
  • Symptoms (Medicine)
DEF

... a severe medication‐induced adverse reaction, which has cutaneous, haematological and solid‐organ features.

OBS

It is one of the triad of life‐threatening drug hypersensitivity dermatoses, along with acute generalized exanthematous pustulosis(AGEP) and Stevens–Johnson syndrome/toxic epidermal necrolysis( SJS/TEN).

French

Domaine(s)
  • Symptômes (Médecine)
DEF

Syndrome allergique grave attribuable à un médicament, très souvent caractérisé par une éruption cutanée importante.

Spanish

Save record 1

Record 2 2018-05-18

English

Subject field(s)
  • Symptoms (Medicine)
  • The Skin
CONT

The designation SCAR most commonly includes Stevens–Johnson syndrome(SJS), toxic epidermal necrolysis( TEN), SJS/TEN overlap, drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivitysyndrome, and acute generalized exanthematous pustulosis.

French

Domaine(s)
  • Symptômes (Médecine)
  • Appareil cutané
CONT

Les symptômes de ces réactions [graves] incluent : une éruption cutanée ou rougeur, qui peut se transformer en réaction cutanée grave comme une éruption cutanée étendue accompagnée de cloques et d'une desquamation, particulièrement autour de la bouche, du nez, des yeux et des parties génitales (syndrome de Stevens-Johnson), desquamation étendue (plus de 30 % de la surface corporelle - nécrolyse épidermique toxique) [...]

Spanish

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Record 3 2001-03-01

English

Subject field(s)
  • The Skin
  • Symptoms (Medicine)
CONT

Toxic epidermal necrolysis(TEN), occurs in adults, often secondary to drugs(e. g., zdrugdatabasez ampicillin, allopurinol) and occasionally to Staphylococcus infections in an immunosuppressed patient. TEN is a reaction to a variety of antigenic materials that cause a suprabasilar split in the epidermis with necrosis of much of the overlying epidermis.

French

Domaine(s)
  • Appareil cutané
  • Symptômes (Médecine)
DEF

Forme grave de toxidermie bulleuse caractérisée par un érythème généralisé avec épidermolyse aiguë.

Spanish

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Record 4 1987-08-04

English

Subject field(s)
  • Epidermis and Dermis
DEF

Necrosis accompanied by the disappearance of keratinocytes.

French

Domaine(s)
  • Épiderme et derme

Spanish

Save record 4

Record 5 1987-08-01

English

Subject field(s)
  • The Heart
CONT

Allergic reactions [to Apo-Sulfatrim include] Erythema multiforme, Stevens-Johnson syndrome, generalized skin eruptions, epidermal necrolysis, urticaria, serum sickness, pruritis, exfoliative dermatitis, anaphylactoid reactions, peri-orbital edema, conjunctival and scleral infection, photosensitization, arthralgia, and allergic myocarditis.

French

Domaine(s)
  • Cœur
CONT

La survenue de ces myocardites allergiques après administration d'un sulfamide ou de pénicilline ou encore après injection d'un sérum notamment antitétanique, est controversée et souvent mal documentée.

Spanish

Save record 5

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