TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

The specific part of an antigen molecule to which an antibody becomes attached.  1, record 1, English, - antigenic%20determinant

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Surface individuelle caractéristique d’un antigène, qui déclenche la production d’un anticorps spécifique au cours de la réponse immunitaire.  1, record 1, French, - d%C3%A9terminant%20antig%C3%A9nique

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Porción específica de un antígeno macromolecular a la que se une un anticuerpo.  2, record 1, Spanish, - determinante%20antig%C3%A9nico

Record number: 1, Textual support number: 1 CONT

Cada determinante antigénico, constituido normalmente por unos pocos aminoácidos, determina la síntesis de un anticuerpo diferente; por tanto, de la exposición a un solo antígeno pueden expresarse varios anticuerpos.  3, record 1, Spanish, - determinante%20antig%C3%A9nico

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

Exhibiting immunocompetence: the ability to produce a normal immune response following exposure to an antigen.  2, record 2, English, - immunocompetent

Record number: 2, Textual support number: 1 CONT

In an immunocompetent individual, the immune response is initiated when introduced to an external agent that possesses an immunogenic structural epitope. The appropriate response depends upon the recognition by surface receptors of B and T lymphocytes of the foreignness of the introduced agent.  1, record 2, English, - immunocompetent

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Qui est immunocompétent; capable de réagir contre un antigène par une réaction immunologique normale.  2, record 2, French, - immunocomp%C3%A9tent

Record number: 2, Textual support number: 1 CONT

Le fonctionnement des cellules immunocompétentes.  1, record 2, French, - immunocomp%C3%A9tent

Record 2,  Textual support,  Spanish

Record number: 2, Textual support number: 1 DEF

[Dícese de] la capacidad del organismo para responder inmunológicamente a la presencia de antígenos.  1, record 2, Spanish, - inmunocompetente

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 OBS

FDA requests more information on OraSure PMA (oral specimen collection device, premarket approval application). Saliva-based AIDS test studied for insurance industry.  2, record 3, English, - OraSure%C2%AE

Record number: 3, Textual support number: 2 OBS

Term and context extracted from the data base.  2, record 3, English, - OraSure%C2%AE

Record number: 3, Textual support number: 3 OBS

A trademark of Epitope Inc. 's OraSure.  2, record 3, English, - OraSure%C2%AE

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 OBS

Marque de commerce de Epitope Inc.'s OraSure.  1, record 3, French, - OraSure%C2%AE

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

The epitope-driven vaccine concept is an attractive one that is being successfully pursued in a number of laboratories... A typical epitope-based vaccine construct contains a single start codon with coding sequences for epitopes inserted consecutively in the construct, with or without intervening spacer amino acids.  2, record 4, English, - epitope%20vaccine

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

La réaction de défense des lymphocytes de l'organisme ne se fait pas sur des protéines entières mais sur des fragments d'acide aminés qui la composent et que l'on appelle des épitopes [...] le vaccin épitopique protège contre l'épitope en question et que contre celui-ci [...]  1, record 4, French, - vaccin%20%C3%A9pitopique

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

ELISPOT(Enzyme-linked ImmunoSPOT) technique was originally used to enumerate antibody secreting B cells. In the current technique, cells are deposited onto a membrane coated with one antibody specific for a protein followed by an appropriate incubation period. Subsequently, the protein of interest is detected in the environment immediately surrounding the cell secreting it, with another antibody specific for a different epitope of the protein.  1, record 5, English, - enzyme%2Dlinked%20immunospot%20technique

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

Des nouvelles méthodes d'exploration de la réponse immune, comme l'Elispot (enzyme-linked immunospot) et l'utilisation par cytométrie en flux de molécules HLA [human leucocyte antigen] solubles, permettent de détecter et de compter les cellules productrices de telle ou telle cytokine. Elles conduisent à des analyses immunologiques très rapides sur des malades volontaires, et à une bien meilleure compréhension de l'histoire naturelle de la maladie.  3, record 5, French, - technique%20ELISPOT

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

The part of an antibody molecule which makes contact with the antigenic determinant(epitope).  2, record 6, English, - paratope

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Le site anticorps (appelé paratope) définit l'idiotype de la molécule et reconnaît sur l'antigène un déterminant appelé épitope. Le site anticorps peut lui-même servir d'antigène pour un autre anticorps, les déterminants antigéniques de l'idiotype étant dénommés idiotopes.  4, record 6, French, - paratope

Record number: 6, Textual support number: 1 OBS

Synonyme d'anticorps dans la terminologie de Jerne.  3, record 6, French, - paratope

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  French

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

Purification of mutant enzymes is a prime requirement of biophysical and biochemical studies. Our investigations on the essential E. Coli enzyme glutaminyl-tRNA sybthetase demand mutant enzymes free of any wild-type protein contamination. However, as it is not possible to express non-complementing mutant enzymes in an E. Coli gInS-deletion strain, we developed a novel strategy to address these problems. Instead of following the common tactic of epitope-tagging the mutant protein of interest on an extrachromosomal genetic element, we fused a reporter epitope to the 5’ end of the chromosomal gInS-gene copy : this is referred as reverse epitope-tagging.  1, record 8, English, - reverse%20epitope%2Dtagging

Record 8,  Textual support,  French

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

A recently developed technology called epitope scanning permits the rapid and accurate delineation of continuous stretches of amino acids in a protein which constitute the sequential epitopes recognised by an antiserum raised to that protein. In the present report, we describe the use of this technique to identify the epitopes in the recombinant bovine growth-hormone(rbGH) molecule recognised by three polyclonal guinea-pig antisera and two polyclonal rabbit antisera. The results obtained show that, for guinea-pig antisera, 3 or 4, very-well-defined major continuous epitopes are present.  2, record 9, English, - recombinant%20bovine%20growth%20hormone

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 OBS

Expression proposée par analogie avec l'expression «hormone de croissance recombinante humaine» tirée de la base de données PASCAL.  1, record 9, French, - hormone%20de%20croissance%20recombinante%20bovine

Record 9,  Textual support,  Spanish