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FACTOR XII [4 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2011-10-21

English

Subject field(s)
  • Biochemistry
  • Biotechnology
CONT

Plasmin is derived from plasminogen, an inert protein precursor that can be activated by tissue factors(called lysokinases) or by contact through factor XII. An activator, urokinase, is also released by blood-vessel lining and is present in normal urine. Certain bacteria produce plasminogen activators, the streptokinase of hemolytic streptococci being the most potent. Plasmin is rapidly destroyed in the bloodstream and normally acts only when taken up by fibrin.

French

Domaine(s)
  • Biochimie
  • Biotechnologie
DEF

Enzyme protéolytique, produit de l'activation du plasminogène, capable de lyser rapidement le caillot de fibrine, de scinder les molécules de fibrinogène, et des facteurs V et VIII.

CONT

Dans le domaine médical, la production de substances importantes sur le plan thérapeutique, par des cellules en culture [...] après introduction du gène correspondant, est une application majeure du génie génétique. Parmi les substances dont la production est, soit déjà une réalité, soit à l'étude, on peut citer : l'insuline [...], l'hormone de croissance [...], les interférons [...], l'activateur du plasminogène (contre les thromboses, car la plasmine est un enzyme qui dégrade la fibrine des caillots).

OBS

Fibrinolysine est un terme vieilli à éviter.

Spanish

Campo(s) temático(s)
  • Bioquímica
  • Biotecnología
Save record 1

Record 2 2011-10-21

English

Subject field(s)
  • Biological Sciences
DEF

Enzyme found in the urine of mammals, including man, and of other vertebrates; it is elaborated by the parenchymal cells of the human kidney and functions as a plasminogen activator. It is used as a thrombolytic (fibrinolytic) agent.

CONT

Plasmin is derived from plasminogen, an inert protein precursor that can be activated by tissue factors(called lysokinases) or by contact through factor XII. An activator, urokinase, is also released by blood-vessel lining and is present in normal urine. Certain bacteria produce plasminogen activators, the streptococci being the most potent. Plasmin is rapidly destroyed in the bloodstream and normally acts only when taken up by ribrin.

French

Domaine(s)
  • Sciences biologiques
DEF

Enzyme extraite de l'urine humaine capable d'activer spécifiquement le plasminogène en plasmine et ayant une activité fibrinolytique. (Elle est utilisée en thérapeutique thrombolytique pour dissoudre des caillots intravasculaires.)

Spanish

Campo(s) temático(s)
  • Ciencias biológicas
Save record 2

Record 3 2003-11-14

English

Subject field(s)
  • Blood
DEF

A factor that initiates blood clotting and one that is deficient in hemophilia.

Key term(s)
  • factor 12

French

Domaine(s)
  • Sang
CONT

Les facteurs de la coagulation. [Le] facteur XII ou facteur Hageman augmente la perméabilité capillaire,

Key term(s)
  • facteur 12

Spanish

Campo(s) temático(s)
  • Sangre
DEF

Proteína plasmática de los mamíferos, que interviene en la mecanismo de la coagulación sanguínea, activando la precalicreína.

Save record 3

Record 4 1998-05-27

English

Subject field(s)
  • Blood
DEF

A powerful phospholipid catalyst in the formation of both intrinsic and extrinsic thromboplastin, acting at the coagulation factor XII and V stages.

French

Domaine(s)
  • Sang
DEF

Phospholipide plaquettaire libéré lors de l'agrégation plaquettaire et jouant un rôle dans la thromboplastinoformation endogène.

Spanish

Save record 4

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