TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
GELSOLIN [6 records]
Record 1 - internal organization data 2012-01-16
Record 1, English
Record 1, Subject field(s)
- Cytology
Record 1, Main entry term, English
- gelsolin
1, record 1, English, gelsolin
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Gelsolin is one of the proteins that regulates the assembly and disassembly of actin filaments. In the presence of calcium, gelsolin severs actin filaments and "caps" their barbed end, preventing the addition of new subunits there. 1, record 1, English, - gelsolin
Record number: 1, Textual support number: 2 CONT
Because [actin-binding proteins] drastically shorten the lengths of the actin filaments, it can convert an actin gel into a sol. We therefore named this protein "gelsolin". 1, record 1, English, - gelsolin
Record number: 1, Textual support number: 1 PHR
Human, mouse, plasma gelsolin. Gelsolin severs actin filaments. Level of gelsolin. 2, record 1, English, - gelsolin
Record number: 1, Textual support number: 2 PHR
To activate gelsolin. 2, record 1, English, - gelsolin
Record 1, French
Record 1, Domaine(s)
- Cytologie
Record 1, Main entry term, French
- gelsoline
1, record 1, French, gelsoline
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La gelsoline est une des protéines qui règlent la formation et la dissociation des filaments d'actine. En présence d'ions calcium, la gelsoline coupe les filaments et coiffe une de leurs extrémités, bloquant l'allongement par cette extrémité. 2, record 1, French, - gelsoline
Record number: 1, Textual support number: 2 CONT
[Les protéines associées à l'actine] coupent [...] les liaisons entre les sous-unités d'actine, faisant apparaître de nouvelles extrémités barbées, qui sont aussitôt coiffées. Ainsi les filaments d'actine sont raccourcis, et le gel d'actine est transformé en sol. Nous avons nommé «gelsoline» la protéine responsable de cette transformation. 2, record 1, French, - gelsoline
Record number: 1, Textual support number: 1 PHR
Gelsoline humaine, de souris, plasmatique. Concentration en gelsoline. La gelsoline fragmente les filaments d'actine. 3, record 1, French, - gelsoline
Record number: 1, Textual support number: 2 PHR
Activer la gelsoline. 3, record 1, French, - gelsoline
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Citología
Record 1, Main entry term, Spanish
- gelsolina
1, record 1, Spanish, gelsolina
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Proteína capaz de ligar actina, dependiente de iones calcio. Posee dos dominios funcionales que se unen independientemente a la actina. 1, record 1, Spanish, - gelsolina
Record 2 - internal organization data 2012-01-16
Record 2, English
Record 2, Subject field(s)
- Cytology
Record 2, Main entry term, English
- polyphosphoinositide
1, record 2, English, polyphosphoinositide
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Lipid molecules called polyphosphoinositides, which are found in the cell membrane, can remove gelsolin from actin filaments and allow them to elongate. 1, record 2, English, - polyphosphoinositide
Record number: 2, Textual support number: 1 OBS
Class of phospholipid molecules [which] is a common constituent of cell membranes and has been implicated in signal transduction within cells ... Lindberg had noticed that polyphosphoinositides could decrease the affinity of profilin, an actin subunit-binding protein [he] discovered in 1977, for actin subunits ... polyphosphoinositides inhibit the actin-binding activity of nearly all proteins that cap and sever actin filaments. 1, record 2, English, - polyphosphoinositide
Record number: 2, Textual support number: 1 PHR
To synthesize, break down polyphosphoinositide. 2, record 2, English, - polyphosphoinositide
Record number: 2, Textual support number: 2 PHR
Polyphosphoinositide degradation. Polyphosphoinositides uncap filaments. Synthesis of polyphosphoinositide. 2, record 2, English, - polyphosphoinositide
Record 2, French
Record 2, Domaine(s)
- Cytologie
Record 2, Main entry term, French
- polyphospho-inositide
1, record 2, French, polyphospho%2Dinositide
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Les polyphospho-inositides sont des phospholipides, c'est-à-dire des molécules composées d'une partie lipidique et d'une tête phosphatée [...] Lindberg avaient observé que les polyphospho-inositides réduisaient l'affinité de la profiline (une des protéines qui se lient à l'actine) pour les sous-unités d'actine [...] les polyphospho-inositides inhibent la fixation de la plupart des protéines qui s'associent à l'actine et qui agissent comme la gelsoline. 1, record 2, French, - polyphospho%2Dinositide
Record number: 2, Textual support number: 1 PHR
Les polyphospho-inositides décoiffent les filaments. 2, record 2, French, - polyphospho%2Dinositide
Record number: 2, Textual support number: 2 PHR
Dégradation des polyphospho-inositides. Synthèse de polyphospho-inositides. 2, record 2, French, - polyphospho%2Dinositide
Record 2, Key term(s)
- polyphosphoinositide
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 1995-01-31
Record 3, English
Record 3, Subject field(s)
- Cytology
Record 3, Main entry term, English
- solation-contraction coupling
1, record 3, English, solation%2Dcontraction%20coupling
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
[Calcium] partially dissolves the actin gel by activating gelsolin and related proteins. The gel must disaggregate sufficiently to allow myosin to move the actin filaments, yet not so extensively that the gel becomes entirely liquid. [This] coordinated event [has been termed by D. Lansing Taylor] "solation-contraction coupling". 1, record 3, English, - solation%2Dcontraction%20coupling
Record 3, French
Record 3, Domaine(s)
- Cytologie
Record 3, Main entry term, French
- couplage entre la transformation gel-sol et la contraction
1, record 3, French, couplage%20entre%20la%20transformation%20gel%2Dsol%20et%20la%20contraction
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Les ions calcium activent la contraction de l'actine corticale en phosphorylant la myosine. Ils dissolvent également le gel d'actine en activant la gelsoline et les protéines apparentées. Le gel doit se dissocier suffisamment pour que la myosine puisse agir sur les filaments d'actine, mais il ne doit pas devenir complément liquide, sans quoi les forces ne s'exercent pas. [Lansing Taylor a baptisé ce procédé] couplage entre la transformation gel-sol et la contraction. 1, record 3, French, - couplage%20entre%20la%20transformation%20gel%2Dsol%20et%20la%20contraction
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 1995-01-31
Record 4, English
Record 4, Subject field(s)
- Cytology
Record 4, Main entry term, English
- actin-scavenging system
1, record 4, English, actin%2Dscavenging%20system
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
Gc globulin and plasma gelsolin may... be parts of an actin-scavenging system [which] may be important in cystic fibrosis, the most common hereditary disorder affecting people of European descent. 1, record 4, English, - actin%2Dscavenging%20system
Record 4, French
Record 4, Domaine(s)
- Cytologie
Record 4, Main entry term, French
- système d'évacuation de l'actine plasmatique
1, record 4, French, syst%C3%A8me%20d%27%C3%A9vacuation%20de%20l%27actine%20plasmatique
correct, masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Gc et la gelsoline circulante disparaissent-elles parce qu'elles sont utilisées pour l'élimination de l'actine plasmatique? On espère que ce système d'évacuation de l'actine plasmatique aidera à lutter contre la mucoviscidose, la maladie génétique la plus importante des individus de type européen. 1, record 4, French, - syst%C3%A8me%20d%27%C3%A9vacuation%20de%20l%27actine%20plasmatique
Record 4, Key term(s)
- système d'élimination de l'actine plasmatique
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 1995-01-31
Record 5, English
Record 5, Subject field(s)
- Cytology
Record 5, Main entry term, English
- capping protein
1, record 5, English, capping%20protein
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
One [subclass of actin-binding proteins] is an extended family of capping proteins with primary structures related to that of gelsolin. 1, record 5, English, - capping%20protein
Record 5, French
Record 5, Domaine(s)
- Cytologie
Record 5, Main entry term, French
- protéine de coiffage
1, record 5, French, prot%C3%A9ine%20de%20coiffage
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Les protéines de «coiffage» [...] ont une structure primaire semblable à celle de la gelsoline. 1, record 5, French, - prot%C3%A9ine%20de%20coiffage
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 1995-01-31
Record 6, English
Record 6, Subject field(s)
- Cytology
Record 6, Main entry term, English
- actin-severing protein
1, record 6, English, actin%2Dsevering%20protein
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
At the trailing edge of the gel, calcium ions reactivate the actin-severing proteins, which loosen the actin network enough for myosin molecules to pull on it... In tests, the actin-severing protein gelsolin was able to thin the mucus of patients [with cystic fibrosis] more efficiently at low concentrations than a type of DNA-cleaving enzyme did. 1, record 6, English, - actin%2Dsevering%20protein
Record 6, French
Record 6, Domaine(s)
- Cytologie
Record 6, Main entry term, French
- protéine de fragmentation de l'actine
1, record 6, French, prot%C3%A9ine%20de%20fragmentation%20de%20l%27actine
correct, feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
Derrière le gel du lamellipode, les ions calcium réactivent les protéines de fragmentation de l'actine, ce qui relâche suffisamment le réseau d'actine pour que les molécules de myosine puissent exercer des forces. 1, record 6, French, - prot%C3%A9ine%20de%20fragmentation%20de%20l%27actine
Record 6, Spanish
Record 6, Textual support, Spanish
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