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HAPLOTYPE [5 records]
Record 1 - internal organization data 2012-07-09
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- haplotype
1, record 1, English, haplotype
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A combination of alleles (DNA sequences) at different places (loci) on the chromosome that are transmitted together. 1, record 1, English, - haplotype
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- haplotype
1, record 1, French, haplotype
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Matériel génétique porté par un seul des deux chromosomes et correspondant à un caractère précis. 2, record 1, French, - haplotype
Record number: 1, Textual support number: 1 CONT
À l'heure actuelle, on a défini cinq loci, désignés par HLA-A, HLA-B, HLA-C, HLA-D et HLA-DR. Chaque locus comporte une série d'allèles. L'ensemble des gènes situés sur un des chromosomes b et transmis par un des parents porte le nom d'haplotype. 3, record 1, French, - haplotype
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
Record 1, Main entry term, Spanish
- haplotipo
1, record 1, Spanish, haplotipo
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Constitución alélica específica para un determinado número de loci dentro de un bloque de ligamiento definido. 2, record 1, Spanish, - haplotipo
Record 2 - internal organization data 2007-01-16
Record 2, English
Record 2, Subject field(s)
- Immunology
Record 2, Main entry term, English
- MHC restriction 1, record 2, English, MHC%20restriction
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
A characteristic of many immune reactions in which cells cooperate most effectively with other cells sharing an MHC haplotype. 2, record 2, English, - MHC%20restriction
Record number: 2, Textual support number: 2 DEF
The phenomenon of certain cell-cell interactions in the immune response occurring only between MHC haploidentical cells. Helper T cells are activated only when the antigen is "seen" in conjunction with self class II MHC antigens (Ia antigens in mice, HLA-DR antigens in humans) antigens (K or D antigens in mice, HLA-A, -B, or -C antigens in humans). 3, record 2, English, - MHC%20restriction
Record 2, French
Record 2, Domaine(s)
- Immunologie
Record 2, Main entry term, French
- cytotoxicité restreinte au CMH
1, record 2, French, cytotoxicit%C3%A9%20restreinte%20au%20CMH
feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- restriction au CMH 2, record 2, French, restriction%20au%20CMH
feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Réactions antivirales; la restriction au CMH : les virus peuvent aussi provoquer l'apparition de lymphocytes T cytotoxiques. [...] Une particularité essentielle de ces réactions cytotoxiques antivirales tient [...] à la nécessité d'une compatibilité au CMH entre la cellule infectée qui a initialement servi à sensibiliser le précurseur des lymphocytes T cytotoxiques et la cellule cible infectée à laquelle le lymphocyte T cytotoxique est confronté au cours de la phase de cytotoxicité. 1, record 2, French, - cytotoxicit%C3%A9%20restreinte%20au%20CMH
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Inmunología
Record 2, Main entry term, Spanish
- restricción del CMH
1, record 2, Spanish, restricci%C3%B3n%20del%20CMH
correct, feminine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2006-05-08
Record 3, English
Record 3, Subject field(s)
- Immunology
Record 3, Main entry term, English
- public specificity 1, record 3, English, public%20specificity
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
H-2 public and private specificities.... Some specificities are shared between antigens and haplotypes, for example specificity 28 is carried on the K and D antigens of both the H-2d and H-2b strains. These are known as public specificities.... A smaller number of specificities are unique to a particular antigen and haplotype and are known as private specificities. 1, record 3, English, - public%20specificity
Record 3, French
Record 3, Domaine(s)
- Immunologie
Record 3, Main entry term, French
- spécificité publique
1, record 3, French, sp%C3%A9cificit%C3%A9%20publique
feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
L'analyse sérologique fine des antigènes H-2 de classe I a révélé l'existence de nombreuses spécificités, privées et publiques. On entend par spécificité privées, les spécificités (H-2D ou H-2K) observées dans un seul haplotype connu. On les oppose aux spécificités publiques qui sont partagées par deux ou plusieurs haplotypes. Chaque haplotype porte au moins un allèle H-2K et un allèle H-2D. Chaque allèle est caractérisé par une spécificité antigénique particulière qui lui est propre (la spécificité privée) et/ou par une ou plusieurs spécificités publiques qu'on peut retrouver sur d'autres allèles. 1, record 3, French, - sp%C3%A9cificit%C3%A9%20publique
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Inmunología
Record 3, Main entry term, Spanish
- especificidad pública
1, record 3, Spanish, especificidad%20p%C3%BAblica
correct, feminine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2006-05-08
Record 4, English
Record 4, Subject field(s)
- Immunology
Record 4, Main entry term, English
- private specificity 1, record 4, English, private%20specificity
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
H-2 public and private specificities.... Some specificities are shared between antigens and haplotypes, for example specificity 28 is carried on the K and D antigens of both the H-2d and H-2b strains. These are known as public specificities.... A smaller number of specificities are unique to a particular antigen and haplotype and are known as private specificities. 1, record 4, English, - private%20specificity
Record 4, French
Record 4, Domaine(s)
- Immunologie
Record 4, Main entry term, French
- spécificité privée
1, record 4, French, sp%C3%A9cificit%C3%A9%20priv%C3%A9e
feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
L'analyse sérologique fine des antigènes H-2 de classe I a révélé l'existence de nombreuses spécificités, privées et publiques. On entend par spécificité privée, les spécificités (H-2D ou H-2K) observées dans un seul haplotype connu. On les oppose aux spécificités publiques qui sont partagées par deux ou plusieurs haplotypes. Chaque haplotype porte au moins un allèle H-2K et un allèle H-2D. Chaque allèle est caractérisé par une spécificité antigénique particulière qui lui est propre (la spécificité privée) et/ou par une ou plusieurs spécificités publiques qu'on peut retrouver sur d'autres allèles. 1, record 4, French, - sp%C3%A9cificit%C3%A9%20priv%C3%A9e
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Inmunología
Record 4, Main entry term, Spanish
- especificidad privada
1, record 4, Spanish, especificidad%20privada
correct, feminine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 1993-02-10
Record 5, English
Record 5, Subject field(s)
- Immunology
Record 5, Main entry term, English
- thymic education 1, record 5, English, thymic%20education
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
... the theory that the pre-T cells developing in the thymus interact with the thymic epithelium, and on maturation only recognize antigen on cells which have the same haplotype as that thymus. 1, record 5, English, - thymic%20education
Record 5, French
Record 5, Domaine(s)
- Immunologie
Record 5, Main entry term, French
- éducation intrathymique
1, record 5, French, %C3%A9ducation%20intrathymique
feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
- éducation intra-thymique 1, record 5, French, %C3%A9ducation%20intra%2Dthymique
feminine noun
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Les mécanismes de la différenciation intrathymique des cellules T (...) semblent faire intervenir (...) un contact direct avec l'épithélium et les cellules phagocytaires du thymus et présentent les antigènes majeurs d'histocompatibilité contre lesquels les cellules T vont s'éduquer. Nous reviendrons sur ce phénomène crucial d'éducation intra-thymique. 1, record 5, French, - %C3%A9ducation%20intrathymique
Record 5, Spanish
Record 5, Textual support, Spanish
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