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HEMOGLOBIN SCALE [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 - external organization data 2021-03-18

English

Subject field(s)
  • Compartment – Nomenclature 4.0
  • Museums and Heritage (General)
OBS

hemoglobin scale : an item in the "Medical and Psychological Tools and Equipment" class of the "Tools and Equipment for Science and Technology" category.

French

Domaine(s)
  • Tiroir – Nomenclature 4.0
  • Muséologie et patrimoine (Généralités)
OBS

échelle colorimétrique de l'hémoglobine : objet de la classe «Outils et équipement médicaux et psychologiques» de la catégorie «Outillage et équipement pour les sciences et la technologie».

Spanish

Save record 1

Record 2 2010-09-15

English

Subject field(s)
  • Biological Sciences
CONT

Triggered conformational changes... are the motions of groups of atoms(i. e. individual side-chains) or whole sections of a protein(i. e. loops of chain, domains of secondary and tertiary structure, or subunit), which occur as a response to a specific stimulus. The distance moved can be as much as 10 [angstrom unit] or more. The time scale can be estimated by studies of the rate of binding or turnover reactions. The energy for triggered conformational change comes from specific interactions, such as electrostatic attractions or hydrogen bonding interactions. The best-known example of a triggered conformational change is the transition in tertiary structure that occurs when ligands bind to the iron atoms of hemoglobin.

OBS

The types of substances whose binding can trigger a specific conformational change include substrates (dihydroxyacetone phosphate in triose phosphate isomerase), coenzymes (NAD binding to lactate dehydrogenase), allosteric effectors (CTP and ATP in aspartic transcarbamylase), inhibitors (statine-containing polypeptide inhibitors of acid proteases) and even protons (the Bohr effect in hemoglobin; pH-dependent conformational changes in adenylate kinase).

French

Domaine(s)
  • Sciences biologiques
DEF

Modification de la conformation des protéines provoquée par la fixation de ligands à leur surface. Parmi ces ligands, notons les substrats, activateurs, inhibiteurs et coenzymes.

Spanish

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