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HEMOLYTIC DISEASE [5 records]

Record 1 2017-12-06

English

Subject field(s)
  • Immunology
DEF

Isoimmunization resulting from exposure to an Rh antigen, formerly the most common cause of hemolytic disease of the newborn.

French

Domaine(s)
  • Immunologie
DEF

Ensemble de manifestations pathologiques ayant pour cause l'immunisation de la mère à un antigène présent sur les cellules du sans fœtal : hématies, leucocytes ou plaquettes.

DEF

Phénomène consécutif aux échanges placentaires qui, au cours de la gestation, peuvent laisser passer le sang du fœtus dans la circulation maternelle. Cette transfusion fœtomaternelle peut aboutir à l'immunisation de la mère contre des antigènes du sang fœtal. [...] Il en résulte l'apparition d'anticorps maternels anti-D, gammaglobulines capables de traverser le placenta et de détruire les hématies D du fœtus [...]

Spanish

Save record 1

Record 2 2012-03-01

English

Subject field(s)
  • Radiography (Medicine)
  • Musculoskeletal System
  • Bones and Joints
DEF

In severe congenital hemolytic anemias, marked new bone formation perpendicular to the tables of the skull, producing a radial hair-on-end appearance. Although most commonly seen in patients with thalassemia, the hair-on-end pattern may also be produced in patients with sickle cell disease or spherocytosis, as well as in some persons with iron-deficiency anemia. [From EISER, 1984, p. 339. ]

OBS

hair-on-end appearance (of the skull)

French

Domaine(s)
  • Radiographie (Médecine)
  • Appareil locomoteur (Médecine)
  • Os et articulations
DEF

Aspect radiologique strié de la voûte crânienne observé au cours de certaines anémies hémolytiques constitutionnelles et notamment dans la thalassémie.

Spanish

Save record 2

Record 3 2005-02-18

English

Subject field(s)
  • Symptoms (Medicine)
  • Blood
OBS

Said of a type of anemia

CONT

Sickel cell disease(drepanocytic anemia) is an hemolytic anemia with RBC assuming characteristic sickle cell shape(drepanocytes) due to abnormal B globin subunit(substitution of valine for glutamic acid at the 6th position from the N-terminus). Roughly 8% of American blacks are heterozygous for the trait.

French

Domaine(s)
  • Symptômes (Médecine)
  • Sang
DEF

Se dit d'une personne atteinte d'anémie falciforme (ou drépanocytose).

Spanish

Save record 3

Record 4 2004-11-04

English

Subject field(s)
  • Liver and Biliary Ducts
DEF

The orange-yellow pigment of bile, formed principally by the breakdown of hemoglobin in red blood cells after termination of their normal lifespan.

OBS

Water-insoluble, unconjugated bilirubin normally travels in the bloodstream to the liver, where it is converted to a water-soluble, conjugated form and excreted into the bile. In a healthy person about 250 mg of bilirubin are produced daily. The majority of bilirubin is excreted in the stool. The characteristic yellow pallor of jaundice is caused by the accumulation of bilirubin in the blood and in the tissues of the skin. Testing for bilirubin in the blood provides information for diagnosis and evaluation of liver disease, biliary obstruction, and hemolytic anemia. Normal levels of total bilirubin are 0. 1 to 1. 0 mg/dl or 5. 1-17. 0 mmol/L.

Key term(s)
  • bilifulvine
  • biliphéine

French

Domaine(s)
  • Foie et voies biliaires
DEF

Pigment jaune-brun provenant de la dégradation de l'hémoglobine (et de quelques autres pigments respiratoires) et constituant le principal colorant de la bile.

OBS

La bilirubine libre, insoluble dans l'eau, est surtout produite dans la rate et la moelle osseuse et transportée jusqu'au foie par l'albumine du foie. La bilirubine conjugée, soluble dans l'eau, est obtenue après transformation chimique dans le foie et excrétée dans la bile.

Spanish

Campo(s) temático(s)
  • Hígado y conductos biliares
OBS

La bilirrubina es liberada por los glóbulos rojos viejos o dañados. Pequeñas cantidades de bilirrubina circulan normalmente en el torrente sanguíneo, hasta que llega al hígado donde se metaboliza para eliminarse posteriormente por los intestinos. Su aumento en la sangre produce la coloración amarilla de la piel llamada ictericia y puede ser indicación de enfermedad hepática o destrucción acelerada y masiva de glóbulos rojos.

Save record 4

Record 5 2002-04-24

English

Subject field(s)
  • Blood
DEF

A rare disease of unknown etiology, usually characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and neurologic abnormalities, fever, renal involvement, proteinuria, hematuria, azotemia, and casts.

French

Domaine(s)
  • Sang
CONT

Le purpura thrombopénique thrombotique, appelé aussi syndrome hémolytique et urémique ou PTT, est un trouble caractérisé par la coagulation anormale et la destruction des globules sanguins, entraînant ainsi une formation de caillots sanguins dans tout le corps.

Spanish

Save record 5

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