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HEPATIC DRUG EXTRACTION [2 records]
Record 1 - internal organization data 1993-01-19
Record 1, English
Record 1, Subject field(s)
- Pharmacology
Record 1, Main entry term, English
- hepatic drug extraction 1, record 1, English, hepatic%20drug%20extraction
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Endocyanine green as an index of hepatic blood flow and/or hepatic drug extraction has been tested and no significant effect has been found. 1, record 1, English, - hepatic%20drug%20extraction
Record 1, French
Record 1, Domaine(s)
- Pharmacologie
Record 1, Main entry term, French
- extraction hépatique d'un médicament
1, record 1, French, extraction%20h%C3%A9patique%20d%27un%20m%C3%A9dicament
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Il a été montré que le coefficient d'extraction hépatique d'un médicament ne dépend pas uniquement de propriétés intrinsèques du foie telles que l'excrétion biliaire ou l'activité des enzymes hépatiques impliquées dans le métabolisme de la molécule. 1, record 1, French, - extraction%20h%C3%A9patique%20d%27un%20m%C3%A9dicament
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 1988-04-20
Record 2, English
Record 2, Subject field(s)
- Pharmacodynamics
Record 2, Main entry term, English
- presystemic metabolism
1, record 2, English, presystemic%20metabolism
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
A particularly important characteristic of drugs that show a high hepatic extraction ratio... is that on oral administration, presystemic metabolism is significant and the amount of drug reaching the systemic circulation may be considerably less than the dose administered. 1, record 2, English, - presystemic%20metabolism
Record 2, French
Record 2, Domaine(s)
- Pharmacodynamie
Record 2, Main entry term, French
- biotransformation hépatique présystémique
1, record 2, French, biotransformation%20h%C3%A9patique%20pr%C3%A9syst%C3%A9mique
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Transformation subie par les médicaments au niveau du foie avant d'atteindre la circulation systémique. 2, record 2, French, - biotransformation%20h%C3%A9patique%20pr%C3%A9syst%C3%A9mique
Record number: 2, Textual support number: 1 CONT
Le foie est l'organe de biotransformation le plus important et contribue à la biotransformation hépatique présystémique plus ou moins importante des médicaments administrés par la voie orale. 3, record 2, French, - biotransformation%20h%C3%A9patique%20pr%C3%A9syst%C3%A9mique
Record 2, Spanish
Record 2, Textual support, Spanish
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