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HEPATIC DRUG EXTRACTION [2 records]

Record 1 1993-01-19

English

Subject field(s)
  • Pharmacology
CONT

Endocyanine green as an index of hepatic blood flow and/or hepatic drug extraction has been tested and no significant effect has been found.

French

Domaine(s)
  • Pharmacologie
CONT

Il a été montré que le coefficient d'extraction hépatique d'un médicament ne dépend pas uniquement de propriétés intrinsèques du foie telles que l'excrétion biliaire ou l'activité des enzymes hépatiques impliquées dans le métabolisme de la molécule.

Spanish

Save record 1

Record 2 1988-04-20

English

Subject field(s)
  • Pharmacodynamics
CONT

A particularly important characteristic of drugs that show a high hepatic extraction ratio... is that on oral administration, presystemic metabolism is significant and the amount of drug reaching the systemic circulation may be considerably less than the dose administered.

French

Domaine(s)
  • Pharmacodynamie
DEF

Transformation subie par les médicaments au niveau du foie avant d'atteindre la circulation systémique.

CONT

Le foie est l'organe de biotransformation le plus important et contribue à la biotransformation hépatique présystémique plus ou moins importante des médicaments administrés par la voie orale.

Spanish

Save record 2

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