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HEPATIC INFLAMMATION [2 records]

Record 1 2024-10-10

English

Subject field(s)
  • Human Diseases - Various
  • Liver and Biliary Ducts
CONT

Metabolic dysfunction-associated steatotic liver disease(MASLD) is one of the most common causes of chronic liver disease in the developed world. It is a spectrum of disease, ranging from hepatic fat accumulation without inflammation to steatohepatitis, fibrosis, cirrhosis, and end-stage liver disease. MASLD is considered the hepatic manifestation of metabolic syndrome and is associated with obesity, dyslipidemia, and type 2 diabetes mellitus. The diagnosis of MASLD is based on [the] exclusion of other etiologies of steatotic liver disease, such as alcohol use, and supportive laboratory tests and imaging.

Key term(s)
  • metabolic dysfunction associated steatotic liver disease

French

Domaine(s)
  • Maladies humaines diverses
  • Foie et voies biliaires
CONT

La maladie du foie associée à un dysfonctionnement métabolique (MASLD [metabolic dysfunction-associated liver disease]) comprend une infiltration graisseuse simple (une maladie bénigne appelée maladie stéatosique hépatique) et la stéatohépatite associée à un dysfonctionnement métabolique (MASH [metabolic dysfunction-associated steatohepatitis]), une variante moins fréquente, mais plus importante.

Spanish

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Record 2 2013-07-18

English

Subject field(s)
  • Liver and Biliary Ducts
CONT

A better understanding of the pathways which regulate hepatic inflammation is a crucial step which offers the potential to identify new molecular targets and design more specific and effective therapeutic treatments for chronic inflammatory liver disease.

French

Domaine(s)
  • Foie et voies biliaires
CONT

Par définition, on identifie une hépatite chronique par la présence d’inflammationhépatique pendant au moins six mois. Cette inflammation se reconnaît par desenzymes hépatiques (AST et ALT) anormalement élevées.

Spanish

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