TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 OBS

Term(s) taken from a Canadian laboratory-equipment company’s catalogue.  1, record 1, English, - hexokinase

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 OBS

Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire.  1, record 1, French, - hexokinase

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

Theory according to which the binding of a substrate to an enzyme may cause conformational changes that align the catalytic groups in their correct orientations.  2, record 2, English, - induced%2Dfit%20theory

Record number: 2, Textual support number: 1 CONT

There is good evidence that yeast hexokinase, which phosphorylates glucose with the terminal phosphate of ATP, involves the induced fit theory. X-ray diffraction studies show that the binding of both the sugar and the nucleotide causes extensive changes in tertiary structure. Also, the binding of the nucleotide to one form of the enzyme is promoted by sugar binding. These results are in accord with earlier solution studies on the ATPase activity of the enzyme in the absence of glucose.  2, record 2, English, - induced%2Dfit%20theory

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Théorie selon laquelle l'interaction enzyme-substrat peut causer un changement conformationnel dans la protéine enzymatique.  2, record 2, French, - th%C3%A9orie%20de%20l%27ajustement%20induit

Record number: 2, Textual support number: 1 CONT

La proposition faite par Koshland dès 1958 considère que le site actif, du fait d'un large déploiement d'amino-acides dans son environnement, possède une certaine flexibilité. De ce fait, au moment de l'entrée du substrat, le site actif réagit en s'adaptant minutieusement à la conformation du substrat et entreprend alors le processus de catalyse. Cette théorie de l'ajustement induit [...] a reçu des supports expérimentaux. Elle permet en outre de comprendre aisément la pénétration du substrat et le départ des produits en fin de réaction.  3, record 2, French, - th%C3%A9orie%20de%20l%27ajustement%20induit

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  French

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

In the immobilized enzyme system, glucose-6-phosphate(G-6-P) produced by the first enzyme reaction, hexokinase, is immediately oxidized by the second enzyme, glucose-6-phosphate dehydrogenase, at a location close to the first one... This is a good example where diffusion resistance is efficiently utilized, and it suggests that the location of enzymes within cells significantly affects the enzyme reaction rate.... When the activity ratio of HK and G-6-PDH is small, the difference between immobilized and free enzymes becomes great..., while when it is high, the difference becomes small. In the latter case, it is considered that as the concentration of G-6-P within the carrier becomes very high due to the high activity of HK, the difference between the two systems becomes less apparent, because rather large amounts of G-6-P are released into the outer solution against the diffusion resistance. That is, when the activity ratio of HK and G-6-PDH is great, the diffusion resistance is not utilized efficiently.  1, record 4, English, - activity%20ratio

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

Bien que, dans l'industrie, les enzymes soient utilisées pour hydrolyser des macromolécules complexes dont les sites de coupures sont souvent inconnus, l'effet global recherché implique généralement l'utilisation d'un type d'enzyme précis. Dans certains cas, tel celui de la pectinase, une enzyme associe trois activités différentes et le rapport des activités doit être assez précis suivant le produit à traiter.  1, record 4, French, - rapport%20des%20activit%C3%A9s

Record 4,  Textual support,  Spanish