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HISTOCOMPATIBILITY ANTIGEN [12 records]
Record 1 - internal organization data 2026-02-24
Record 1, English
Record 1, Subject field(s)
- Immunology
- Molecular Biology
Record 1, Main entry term, English
- immunopeptidomics
1, record 1, English, immunopeptidomics
correct, noun
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Immunopeptidomics combines proteomics and immunology to study the antigen repertoire, or the immunopeptidome, by assessing MHC [major histocompatibility complex] bound peptides isolated from biological samples using mass spectrometry for quantitative analysis and characterization.... Immunopeptidomics aids in understanding disease pathogenesis, particularly autoimmune disease and cancers, by using mass spectrometry to quantitatively analyze MHC associated peptides in the immunopeptidome. 1, record 1, English, - immunopeptidomics
Record 1, French
Record 1, Domaine(s)
- Immunologie
- Biologie moléculaire
Record 1, Main entry term, French
- immunopeptidomique
1, record 1, French, immunopeptidomique
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
L'immunopeptidomique est un domaine émergent se référant à la science qui étudie l'ensemble des peptides (ou ligands) liés aux molécules du complexe majeur d'histocomptabilité (CMH). Ces peptides jouent un rôle fondamental dans la réponse immunitaire médiée par les lymphocytes T, et représentent donc des cibles de choix pour le développement de vaccins ou d'immunothérapies contre le cancer, les maladies auto-immunes et infectieuses. 1, record 1, French, - immunopeptidomique
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Inmunología
- Biología molecular
Record 1, Main entry term, Spanish
- inmunopeptidómica
1, record 1, Spanish, inmunopeptid%C3%B3mica
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
La inmunopeptidómica, como el análisis de péptidos antigénicos que se presentan al sistema inmunológico a través de complejos mayores de histocompatibilidad (MHC), se está viendo como una herramienta imperativa para identificar epítopos para el desarrollo de vacunas para tratar el cáncer, así como infecciones virales, bacterianas y parásitos. 1, record 1, Spanish, - inmunopeptid%C3%B3mica
Record 2 - internal organization data 2017-12-19
Record 2, English
Record 2, Subject field(s)
- Immunology
Record 2, Main entry term, English
- minor histocompatibility antigen 1, record 2, English, minor%20histocompatibility%20antigen
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
A system of allelic alloantigens that can cause transplant rejection, but with a long delay (up to 100 days); about 15-30 such systems have been found in mice. 1, record 2, English, - minor%20histocompatibility%20antigen
Record 2, French
Record 2, Domaine(s)
- Immunologie
Record 2, Main entry term, French
- antigène mineur d'histocompatibilité
1, record 2, French, antig%C3%A8ne%20mineur%20d%27histocompatibilit%C3%A9
masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
L'intervention d'antigènes non HLA dans le rejet des greffes est démontré par l'observation des crises de rejet chez des receveurs d'une allogreffe de rein provenant de frère ou sœur HLA identique (à la fois pour les locus de classe I ou II) et de réactions de greffe contre hôte après greffe de moelle entre frères ou sœurs HLA identique. Les antigènes mineurs d'histocompatibilité en cause sont encore mal connus. 1, record 2, French, - antig%C3%A8ne%20mineur%20d%27histocompatibilit%C3%A9
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Inmunología
Record 2, Main entry term, Spanish
- antígeno de histocompatibilidad menor
1, record 2, Spanish, ant%C3%ADgeno%20de%20histocompatibilidad%20menor
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2017-04-19
Record 3, English
Record 3, Subject field(s)
- Cytology
- Surgery
Record 3, Main entry term, English
- passenger cell
1, record 3, English, passenger%20cell
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
In a graft, cells that are not part of the essential structure of the tissue or organ being transplanted. 2, record 3, English, - passenger%20cell
Record number: 3, Textual support number: 1 CONT
Histocompatibility antigen and passenger cell content of normal and diseased human cornea 3, record 3, English, - passenger%20cell
Record 3, French
Record 3, Domaine(s)
- Cytologie
- Chirurgie
Record 3, Main entry term, French
- cellule passagère
1, record 3, French, cellule%20passag%C3%A8re
feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Cellules passagères dans des allogreffes de cœur de rat. Pas d'effet de leur élimination. 1, record 3, French, - cellule%20passag%C3%A8re
Record number: 3, Textual support number: 2 CONT
Cellules passagères immunologiquement compétentes dans la peau de souris. 1, record 3, French, - cellule%20passag%C3%A8re
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2012-09-10
Record 4, English
Record 4, Subject field(s)
- Genetics
- Immunology
Record 4, Main entry term, English
- T lymphocyte antigen receptor
1, record 4, English, T%20lymphocyte%20antigen%20receptor
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
- T-cell receptor 1, record 4, English, T%2Dcell%20receptor
correct
- TCR 1, record 4, English, TCR
correct
- TCR 1, record 4, English, TCR
- T lymphocyte receptor 1, record 4, English, T%20lymphocyte%20receptor
correct
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
A molecule on the surface membrane of T lymphocytes capable of specifically binding antigen in association with MHC [major histocompatibility complex], leading to activation of the cell... 1, record 4, English, - T%20lymphocyte%20antigen%20receptor
Record 4, French
Record 4, Domaine(s)
- Génétique
- Immunologie
Record 4, Main entry term, French
- récepteur de l'antigène des lymphocytes T
1, record 4, French, r%C3%A9cepteur%20de%20l%27antig%C3%A8ne%20des%20lymphocytes%20T
correct, masculine noun
Record 4, Abbreviations, French
- TCR 2, record 4, French, TCR
correct
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Des récepteurs spécifiques exprimés par les cellules immuno-compétentes reconnaissent les antigènes : l'immunoglobuline membranaire exprimée par les lymphocytes B (BcR) les reconnaît sous forme soluble; le récepteur de l'antigène des lymphocytes T (TcR) reconnaît le complexe peptide antigénique-CMH [complexe majeur d'histocompatibilité] exprimé à la surface des cellules présentatrices. 1, record 4, French, - r%C3%A9cepteur%20de%20l%27antig%C3%A8ne%20des%20lymphocytes%20T
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Genética
- Inmunología
Record 4, Main entry term, Spanish
- receptor de células T
1, record 4, Spanish, receptor%20de%20c%C3%A9lulas%20T
correct, masculine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record number: 4, Textual support number: 1 DEF
Proteína de unión a un antígeno, localizada en la superficie de los linfocitos citolíticos de los mamíferos, que actúa como un mediador en la respuesta inmunitaria celular. 1, record 4, Spanish, - receptor%20de%20c%C3%A9lulas%20T
Record number: 4, Textual support number: 1 CONT
Los genes que codifican las regiones variables de las células T (donde se encuentran los centros de unión al antígeno) se agrupan a partir de segmentos génicos mediante procesos de recombinación somática que tienen lugar durante la diferenciación de los linfocitos. 1, record 4, Spanish, - receptor%20de%20c%C3%A9lulas%20T
Record 5 - internal organization data 2012-06-26
Record 5, English
Record 5, Subject field(s)
- Immunology
Record 5, Main entry term, English
- desetope 1, record 5, English, desetope
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
This is the part of the MHC(major histocompatibility complex) molecule which binds to the antigen. It determines the orientation of the antigen and so which part will be presented to the T cell(derivation : determinant selection). Allotypically different class 2 molecules with different desetopes would vary in the way they associate with antigen and thus in how they stimulate T cells. In this way they could determine immune response(Ir genes). 2, record 5, English, - desetope
Record 5, French
Record 5, Domaine(s)
- Immunologie
Record 5, Main entry term, French
- désétope
1, record 5, French, d%C3%A9s%C3%A9tope
masculine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 DEF
Partie de la molécule du CMH associée à l'antigène ou à l'antigène digéré. 2, record 5, French, - d%C3%A9s%C3%A9tope
Record number: 5, Textual support number: 1 OBS
Déterminant de l'histotope. 3, record 5, French, - d%C3%A9s%C3%A9tope
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Inmunología
Record 5, Main entry term, Spanish
- desetopo
1, record 5, Spanish, desetopo
correct, masculine noun
Record 5, Abbreviations, Spanish
Record 5, Synonyms, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2011-11-07
Record 6, English
Record 6, Subject field(s)
- Immunology
Record 6, Main entry term, English
- immunological receptor
1, record 6, English, immunological%20receptor
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
- immunologic receptor 1, record 6, English, immunologic%20receptor
correct
- immumoreceptor 2, record 6, English, immumoreceptor
correct
Record 6, Textual support, English
Record number: 6, Textual support number: 1 DEF
A cell surface molecules on cell of the immune system that specifically binds surface molecules or messenger molecules and trigger changes in the behavior of cells. 1, record 6, English, - immunological%20receptor
Record number: 6, Textual support number: 1 CONT
Cells of the immune system expres s a wide variety of receptors, defined as immunoreceptors. These receptors are involved in antigen recognition, B and T lymphocytes express clonally distributed receptors which recognize soluble antigen for the B cell receptor(BcR) or peptide associated to major histocompatibility complex(MHC) molecules for the T cell receptor(TcR). 3, record 6, English, - immunological%20receptor
Record number: 6, Textual support number: 1 OBS
Although these receptors were first identified in the immune system, many have important functions elsewhere. 1, record 6, English, - immunological%20receptor
Record 6, French
Record 6, Domaine(s)
- Immunologie
Record 6, Main entry term, French
- récepteur immunologique
1, record 6, French, r%C3%A9cepteur%20immunologique
correct, masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
- immunorécepteur 2, record 6, French, immunor%C3%A9cepteur
correct, masculine noun
Record 6, Textual support, French
Record number: 6, Textual support number: 1 DEF
Récepteur spécifique exprimé par les cellules immunocompétentes. 3, record 6, French, - r%C3%A9cepteur%20immunologique
Record number: 6, Textual support number: 1 CONT
Signalisation et transport cellulaire des immunorécepteurs. Des récepteurs spécifiques exprimés par les cellules immunocompétentes reconnaissent les antigènes: l'immunoglobuline membranaire exprimée par les lymphocytes B (BcR) les reconnaît sous forme soluble; le récepteur de l'antigène des lymphocytes T (TcR) reconnaît le complexe peptide antigénique-CMH exprimé à la surface des cellules présentatrices. 2, record 6, French, - r%C3%A9cepteur%20immunologique
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Inmunología
Record 6, Main entry term, Spanish
- inmunorreceptor
1, record 6, Spanish, inmunorreceptor
correct, masculine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2006-05-08
Record 7, English
Record 7, Subject field(s)
- Genetics
Record 7, Main entry term, English
- antigenic receptor
1, record 7, English, antigenic%20receptor
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 CONT
The T cell antigen receptor is the key to the cells activity. The receptor consists of one alpha-chain protein and one beta-chain protein. The receptor is fussy : it can bind only with a single type of antigen, which must be held by specific major histocompatibility(MHC) proteins on the surface of cells. 1, record 7, English, - antigenic%20receptor
Record 7, French
Record 7, Domaine(s)
- Génétique
Record 7, Main entry term, French
- récepteur antigénique
1, record 7, French, r%C3%A9cepteur%20antig%C3%A9nique
correct
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record 7, Spanish
Record 7, Campo(s) temático(s)
- Genética
Record 7, Main entry term, Spanish
- receptor antigénico
1, record 7, Spanish, receptor%20antig%C3%A9nico
correct, masculine noun
Record 7, Abbreviations, Spanish
Record 7, Synonyms, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 2003-06-10
Record 8, English
Record 8, Subject field(s)
- Genetics
Record 8, Main entry term, English
- histocompatibility antigen
1, record 8, English, histocompatibility%20antigen
correct
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record number: 8, Textual support number: 1 DEF
Any of the genetically determined antigens present on the cells of most tissues. 2, record 8, English, - histocompatibility%20antigen
Record number: 8, Textual support number: 1 OBS
histocompatibility : in tissue allografting, absence of an immune response by the potential donor to the recipient's antigen. 2, record 8, English, - histocompatibility%20antigen
Record 8, French
Record 8, Domaine(s)
- Génétique
Record 8, Main entry term, French
- antigène d'histocompatibilité
1, record 8, French, antig%C3%A8ne%20d%27histocompatibilit%C3%A9
correct, masculine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 DEF
Protéine de la surface des cellules qui caractérise chaque tissu de l'individu grâce à un label biologique unique. 2, record 8, French, - antig%C3%A8ne%20d%27histocompatibilit%C3%A9
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Genética
Record 8, Main entry term, Spanish
- antígeno de histocompatibilidad
1, record 8, Spanish, ant%C3%ADgeno%20de%20histocompatibilidad
correct, masculine noun
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
- antígeno de trasplante 1, record 8, Spanish, ant%C3%ADgeno%20de%20trasplante
correct, masculine noun
Record 8, Textual support, Spanish
Record 9 - internal organization data 1993-03-02
Record 9, English
Record 9, Subject field(s)
- Immunology
Record 9, Main entry term, English
- class I antigen
1, record 9, English, class%20I%20antigen
correct
Record 9, Abbreviations, English
Record 9, Synonyms, English
- class I MHC molecule 2, record 9, English, class%20I%20MHC%20molecule
Record 9, Textual support, English
Record number: 9, Textual support number: 1 DEF
(Each of) major histocompatibility antigens found on virtually every cell, human erythrocytes being the only notable exception; they are found on molecules consisting of two noncovalently bound chains. One on 44,000-dalton polymorphic glycoprotein partially embedded in the cell membrane, is determined by an MHC gene(HLA-A, -B, or -C in humans); the other, [beta]2-microglobulin, a 12,000-dalton nonopolymorphic protein, is determined by a non-MHC gene. Class I antigens are the classic histocompatibility antigens recognized during graft rejection.... 3, record 9, English, - class%20I%20antigen
Record number: 9, Textual support number: 2 DEF
Histocompatibility antigen composed of two non-covalently associated, glycosylated polypeptides : a heavy chain of M. Wt. 44 000 and beta squared-microglobulin, M. Wt. 12 000. 4, record 9, English, - class%20I%20antigen
Record 9, French
Record 9, Domaine(s)
- Immunologie
Record 9, Main entry term, French
- antigène de classe I
1, record 9, French, antig%C3%A8ne%20de%20classe%20I
correct, masculine noun
Record 9, Abbreviations, French
Record 9, Synonyms, French
- CMH de classe I 2, record 9, French, CMH%20de%20classe%20I
Record 9, Textual support, French
Record number: 9, Textual support number: 1 CONT
Différentes approches ont permis de définir deux catégories d'antigènes d'histocompatibilité : les antigènes de classe I qui stimulent puis qui sont la cible de la réaction de lymphocytotoxicité due aux cellules T et les antigènes de classe II (...). (...) Les antigènes de classe I ont une distribution tissulaire ubiquitaire sur les cellules diploïdes (...). Les antigènes de classe I sont composés d'une chaîne lourde polymorphe (45 kDa) codée dans le CMH, associée à la [bêta]2-microglobuline non polymorphe qui est codée en dehors du CMH. 3, record 9, French, - antig%C3%A8ne%20de%20classe%20I
Record number: 9, Textual support number: 2 CONT
(...) la plupart des cellules cytotoxiques reconnaissent les antigènes viraux en association avec les antigènes de classe I ce qui conforte cette hypothèse, puisque ces antigènes sont présents sur la majorité des cellules. 4, record 9, French, - antig%C3%A8ne%20de%20classe%20I
Record 9, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 1993-02-19
Record 10, English
Record 10, Subject field(s)
- Immunology
Record 10, Main entry term, English
- lymphocyte-defined antigen 1, record 10, English, lymphocyte%2Ddefined%20antigen
Record 10, Abbreviations, English
Record 10, Synonyms, English
- LD antigen 1, record 10, English, LD%20antigen
Record 10, Textual support, English
Record number: 10, Textual support number: 1 DEF
(Any) major histocompatibility antigen defined and typed by the mixed lymphocyte reaction(MLR), e. g., HLA-D antigens. 1, record 10, English, - lymphocyte%2Ddefined%20antigen
Record 10, French
Record 10, Domaine(s)
- Immunologie
Record 10, Main entry term, French
- antigène LD
1, record 10, French, antig%C3%A8ne%20LD
masculine noun
Record 10, Abbreviations, French
Record 10, Synonyms, French
Record 10, Textual support, French
Record number: 10, Textual support number: 1 CONT
La réaction lymphocytaire mixte (...) les antigènes de transplantation stimulant la réaction lymphocytaire mixte sont différents de ceux induisant la production d'anticorps de transplantation. On oppose les antigènes SD (sero-defined), de classe I, donnant lieu à une production d'anticorps, aux antigènes LD (lymphocyte-defined), de classe II, stimulant une réaction lymphocytaire mixte. 1, record 10, French, - antig%C3%A8ne%20LD
Record 10, Spanish
Record 10, Textual support, Spanish
Record 11 - internal organization data 1993-02-19
Record 11, English
Record 11, Subject field(s)
- Immunology
Record 11, Main entry term, English
- HLA-DR antigen 1, record 11, English, HLA%2DDR%20antigen
Record 11, Abbreviations, English
Record 11, Synonyms, English
Record 11, Textual support, English
Record number: 11, Textual support number: 1 CONT
Human leukocyte antigen... governed by genes of the HLA complex(the human major histocompatibility complex), a region of the short arm of chromosome 6 containing several genetic loci, each having multiple alleles. Loci are designated by letters, HLA-A,-B,-C,-DP,-DQ,-DR(there are at least three sub-loci in the D region),-MB, MT, and Te, and alleles at each locus by numbers, e. g., HLA-A1, provisional designations being indicated by "w"(for "workshop"), e. g., HLA-DRw10.... 1, record 11, English, - HLA%2DDR%20antigen
Record 11, French
Record 11, Domaine(s)
- Immunologie
Record 11, Main entry term, French
- antigène HLA-DR
1, record 11, French, antig%C3%A8ne%20HLA%2DDR
masculine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
Record 11, Textual support, French
Record number: 11, Textual support number: 1 CONT
Les antigènes HLA-DR [...] sont présents sur un faible nombre de cellules de l'organisme : les lymphocytes B, les lymphocytes T activés, notamment par la PHA et les lymphocytes T cytotoxiques, les macrophages, les cellules endothéliales des vaisseaux, les cellules épidermiques et les spermatozoïdes. Les études ont montré qu'ils étaient codés par un locus proche du locus HLA-D d'où leur dénomination d'antigènes DR (D related). 1, record 11, French, - antig%C3%A8ne%20HLA%2DDR
Record 11, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 1991-10-22
Record 12, English
Record 12, Subject field(s)
- Genetics
Record 12, Main entry term, English
- alpha-chain protein
1, record 12, English, alpha%2Dchain%20protein
correct
Record 12, Abbreviations, English
Record 12, Synonyms, English
Record 12, Textual support, English
Record number: 12, Textual support number: 1 CONT
The T cell antigen receptor is the key to the cells activity. The receptor consists of one alpha-chain protein and one beta-chain protein. The receptor is fussy : it can bind only with a single type of antigen, which must be held by specific major histocompatibility complex(MHC) proteins on the surface of cells. 1, record 12, English, - alpha%2Dchain%20protein
Record 12, French
Record 12, Domaine(s)
- Génétique
Record 12, Main entry term, French
- chaîne protéinique alpha
1, record 12, French, cha%C3%AEne%20prot%C3%A9inique%20alpha
correct, feminine noun
Record 12, Abbreviations, French
Record 12, Synonyms, French
Record 12, Textual support, French
Record 12, Spanish
Record 12, Textual support, Spanish
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