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HISTONES [12 records]
Record 1 - internal organization data 2025-02-26
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- epigenetic mark
1, record 1, English, epigenetic%20mark
correct, noun
Record 1, Abbreviations, English
Record 1, Synonyms, English
- epigenetic tag 2, record 1, English, epigenetic%20tag
correct, noun
- epimark 3, record 1, English, epimark
correct, noun
- epi-mark 4, record 1, English, epi%2Dmark
correct, noun
- epi-tag 5, record 1, English, epi%2Dtag
correct, noun
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Epigenetic tags regulate gene expression by acting as gatekeepers, blocking or allowing access to a gene's "on" switch. These chemical tags(such as methyl or acetyl groups) are added directly to DNA or onto histones, the large spool-like proteins around which DNA is tightly wound. 6, record 1, English, - epigenetic%20mark
Record 1, Key term(s)
- epi tag
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- marque épigénétique
1, record 1, French, marque%20%C3%A9pig%C3%A9n%C3%A9tique
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- marqueur épigénétique 2, record 1, French, marqueur%20%C3%A9pig%C3%A9n%C3%A9tique
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Groupement chimique, en particulier méthyle ou acétyle, qui est fixé à l'ADN ou aux histones et qui module la transcription des gènes, notamment en conditionnant le degré de condensation de la chromatine. 3, record 1, French, - marque%20%C3%A9pig%C3%A9n%C3%A9tique
Record number: 1, Textual support number: 1 OBS
marque épigénétique; marqueur épigénétique : désignations et définition publiées au Journal officiel de la République française le 27 juillet 2023. 4, record 1, French, - marque%20%C3%A9pig%C3%A9n%C3%A9tique
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2015-02-24
Record 2, English
Record 2, Subject field(s)
- Genetics
- Biochemistry
Record 2, Main entry term, English
- histone acetyltransferase
1, record 2, English, histone%20acetyltransferase
correct
Record 2, Abbreviations, English
- HAT 1, record 2, English, HAT
correct
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
... an enzyme that acetylates core histones, which results in important regulatory effects on chromatin structure and assembly, and gene transcription. 1, record 2, English, - histone%20acetyltransferase
Record 2, French
Record 2, Domaine(s)
- Génétique
- Biochimie
Record 2, Main entry term, French
- histone acétyltransférase
1, record 2, French, histone%20ac%C3%A9tyltransf%C3%A9rase
correct, feminine noun
Record 2, Abbreviations, French
- HAT 2, record 2, French, HAT
correct, feminine noun
Record 2, Synonyms, French
Record 2, Textual support, French
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2013-11-15
Record 3, English
Record 3, Subject field(s)
- Genetics
Record 3, Main entry term, English
- deoxyribonucleoprotein
1, record 3, English, deoxyribonucleoprotein
correct
Record 3, Abbreviations, English
- DNP 2, record 3, English, DNP
correct
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
Protein held by electrostatic forces in association with deoxyribonucleic acid(DNA) of the nucleus. The low-molecular-weight protamines(nucleoprotamines), and histones(nucleohistones) both basic proteins, are isolated from cell nuclei and sperm-heads. Nucleoprotamines are thought to occupy the minor(shallow) groove of the DNA helix. Nucleohistones have been proposed to be repressors to the expression of certain tracts of the DNA in gene translation. 2, record 3, English, - deoxyribonucleoprotein
Record 3, French
Record 3, Domaine(s)
- Génétique
Record 3, Main entry term, French
- désoxyribonucléoprotéine
1, record 3, French, d%C3%A9soxyribonucl%C3%A9oprot%C3%A9ine
correct, feminine noun
Record 3, Abbreviations, French
- DNP 2, record 3, French, DNP
correct
Record 3, Synonyms, French
- désoxyribonucléoprotéide 2, record 3, French, d%C3%A9soxyribonucl%C3%A9oprot%C3%A9ide
correct, feminine noun
- DNP 2, record 3, French, DNP
correct
- DNP 2, record 3, French, DNP
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Molécule constituée de protéines à caractère basique, associées dans le noyau cellulaire aux acides désoxyribonucléiques et qui interviendraient dans la transmission du message génétique. 2, record 3, French, - d%C3%A9soxyribonucl%C3%A9oprot%C3%A9ine
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2011-08-09
Record 4, English
Record 4, Subject field(s)
- Biological Sciences
- Biotechnology
Record 4, Main entry term, English
- globular protein
1, record 4, English, globular%20protein
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
Protein soluble in water, usually with added acid, alkali, salt or ethanol. Roughly so classified are : albumins, globulins, histones, and protamines. 2, record 4, English, - globular%20protein
Record number: 4, Textual support number: 1 CONT
In globular proteins, disulfide bonds provide conformational stability, although the detailed mechanisms by which these bonds influence not only the stability of native structures but also pathways of folding and unfolding have yet to be defined ... The flexibility of the polypeptide backbone and of the side chains is what enables each globular protein to fold into its characteristic native, or average, structure. 3, record 4, English, - globular%20protein
Record 4, French
Record 4, Domaine(s)
- Sciences biologiques
- Biotechnologie
Record 4, Main entry term, French
- protéine globulaire
1, record 4, French, prot%C3%A9ine%20globulaire
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 DEF
Protéine constituée de chaînes polypeptidiques étroitement repliées en des formes compactes sphériques ou globulaires. La plupart de ces protéines sont solubles dans les systèmes aqueux et diffusent aisément. Elles sont habituellement dans les cellules. 2, record 4, French, - prot%C3%A9ine%20globulaire
Record number: 4, Textual support number: 1 CONT
La myoglobine, la molécule qui stocke l'oxygène dans les muscles, est une protéine globulaire dont les déformations moléculaires jouent un rôle fonctionnel important. Chez les baleines, par exemple, la myoglobine est présente en grande quantité et c'est elle qui permet à l'animal de respirer lorsqu'il plonge. 3, record 4, French, - prot%C3%A9ine%20globulaire
Record number: 4, Textual support number: 1 OBS
Parmi les 2000 enzymes environ connus à ce jour, presque tous sont des protéines globulaires, comme le sont les anticorps, des hormones et de nombreuses protéines possédant des fonctions de transport, comme l'albumine sérique et l'hémoglobine. 2, record 4, French, - prot%C3%A9ine%20globulaire
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Ciencias biológicas
- Biotecnología
Record 4, Main entry term, Spanish
- proteína globular
1, record 4, Spanish, prote%C3%ADna%20globular
correct, feminine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2007-01-16
Record 5, English
Record 5, Subject field(s)
- Immunology
Record 5, Main entry term, English
- antinuclear antibody
1, record 5, English, antinuclear%20antibody
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
An autoantibody directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. 1, record 5, English, - antinuclear%20antibody
Record 5, French
Record 5, Domaine(s)
- Immunologie
Record 5, Main entry term, French
- anticorps antinucléaire
1, record 5, French, anticorps%20antinucl%C3%A9aire
correct, masculine noun
Record 5, Abbreviations, French
- AAN 1, record 5, French, AAN
correct, masculine noun
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 DEF
Autoanticorps dirigés contre plusieurs antigènes nucléaires comprenant l'ADN, l'ARN, les histones, les protéines nucléaires acides, ou des complexes de ces éléments moléculaires. 1, record 5, French, - anticorps%20antinucl%C3%A9aire
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Inmunología
Record 5, Main entry term, Spanish
- anticuerpo antinuclear
1, record 5, Spanish, anticuerpo%20antinuclear
correct, masculine noun
Record 5, Abbreviations, Spanish
- AAN 2, record 5, Spanish, AAN
correct, masculine noun
Record 5, Synonyms, Spanish
Record 5, Textual support, Spanish
Record number: 5, Textual support number: 1 DEF
Anticuerpos que el organismo crea contra sí mismo en algunas enfermedades autoinmunes. 3, record 5, Spanish, - anticuerpo%20antinuclear
Record number: 5, Textual support number: 1 CONT
La inmunofluorescencia se emplea generalmente para detectar y cuantificar el anticuerpo antinuclear (AAN), el cual es un anticuerpo que el organismo crea contra sí mismo en algunas enfermedades autoinmunes, como LES [lupus eritromatoso sistémico]. 3, record 5, Spanish, - anticuerpo%20antinuclear
Record 6 - internal organization data 2003-06-05
Record 6, English
Record 6, Subject field(s)
- Genetics
Record 6, Main entry term, English
- nucleosome
1, record 6, English, nucleosome
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
- nu particle 2, record 6, English, nu%20particle
correct
- nu body 2, record 6, English, nu%20body
correct
Record 6, Textual support, English
Record number: 6, Textual support number: 1 DEF
A structure occurring in eukaryotic chromosomes that consists of a spherical particle containing two molecules each of the histones H2a, H2b, H3, and H4, plus a length of DNA of about 140 base pairs tightly coiled around the outside. 3, record 6, English, - nucleosome
Record 6, French
Record 6, Domaine(s)
- Génétique
Record 6, Main entry term, French
- nucléosome
1, record 6, French, nucl%C3%A9osome
correct, masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
- particule nu 2, record 6, French, particule%20nu
correct, feminine noun
Record 6, Textual support, French
Record number: 6, Textual support number: 1 DEF
Élément de la chromatine formé par l'enroulement du DNA (140 paires de bases) sur un octamère d'histones (une paire de H2A, H2B, H3 et H4). 3, record 6, French, - nucl%C3%A9osome
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Genética
Record 6, Main entry term, Spanish
- nucleosoma
1, record 6, Spanish, nucleosoma
correct, masculine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2003-06-03
Record 7, English
Record 7, Subject field(s)
- Genetics
- Biochemistry
Record 7, Main entry term, English
- chromosome
1, record 7, English, chromosome
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
- chromatosome 2, record 7, English, chromatosome
correct, obsolete
Record 7, Textual support, English
Record number: 7, Textual support number: 1 DEF
In animal cells, a structure in the nucleus containing a linear thread of DNA, which transmits genetic information and is associated with RNA and histones. 3, record 7, English, - chromosome
Record 7, French
Record 7, Domaine(s)
- Génétique
- Biochimie
Record 7, Main entry term, French
- chromosome
1, record 7, French, chromosome
correct, masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 DEF
Élément permanent du noyau cellulaire porteur du patrimoine génétique de l'individu. 2, record 7, French, - chromosome
Record number: 7, Textual support number: 1 OBS
Définition attribuée à Strasburger et Flemming, 1882. 2, record 7, French, - chromosome
Record 7, Spanish
Record 7, Campo(s) temático(s)
- Genética
- Bioquímica
Record 7, Main entry term, Spanish
- cromosoma
1, record 7, Spanish, cromosoma
correct, masculine noun
Record 7, Abbreviations, Spanish
Record 7, Synonyms, Spanish
Record 7, Textual support, Spanish
Record number: 7, Textual support number: 1 DEF
Estructura en forma de bastón que se encuentra en el núcleo de la célula y aparece en la división celular. El cromosoma está constituido por genes, los cuales son portadores de toda la información genética codificada en el ADN. 2, record 7, Spanish, - cromosoma
Record number: 7, Textual support number: 1 CONT
El ser humano presenta 23 pares de cromosomas. 2, record 7, Spanish, - cromosoma
Record 8 - internal organization data 2002-09-17
Record 8, English
Record 8, Subject field(s)
- Genetics
- Biochemistry
Record 8, Main entry term, English
- histone
1, record 8, English, histone
correct
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record number: 8, Textual support number: 1 DEF
Any of the strong, solluble basic proteins of cell nuclei that are precipated by ammonium hydroxide. 2, record 8, English, - histone
Record number: 8, Textual support number: 1 CONT
In 1950 E. and E. Stedman proposed... that the histones constituents of chromosomes in higher organisms play a role in controlling gene action. 3, record 8, English, - histone
Record 8, French
Record 8, Domaine(s)
- Génétique
- Biochimie
Record 8, Main entry term, French
- histone
1, record 8, French, histone
correct, feminine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 DEF
Protéine basique, constituant majeur du nucléosome. 2, record 8, French, - histone
Record number: 8, Textual support number: 1 CONT
Il faut souligner que les histones, constituants normaux des chromosomes, pourraient jouer un rôle important dans la régulation de l'activité des gènes. 3, record 8, French, - histone
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Genética
- Bioquímica
Record 8, Main entry term, Spanish
- histona
1, record 8, Spanish, histona
feminine noun
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
Record 8, Textual support, Spanish
Record 9 - internal organization data 2001-11-13
Record 9, English
Record 9, Subject field(s)
- Genetics
Record 9, Main entry term, English
- chromatin
1, record 9, English, chromatin
correct
Record 9, Abbreviations, English
Record 9, Synonyms, English
Record 9, Textual support, English
Record number: 9, Textual support number: 1 DEF
The material of which chromosomes are composed, a complex of DNA and histones. It is found in the cell nucleus and is the carrier of the genes. 2, record 9, English, - chromatin
Record number: 9, Textual support number: 1 OBS
The uncoiled, less readily stained chromatin is called extended chromatin or euchromatin; the tightly coiled, more readily stained chromatin is condensed chromatin or heterochromatin. 2, record 9, English, - chromatin
Record 9, French
Record 9, Domaine(s)
- Génétique
Record 9, Main entry term, French
- chromatine
1, record 9, French, chromatine
correct, feminine noun
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 DEF
Substance de base des chromosomes des organismes eucaryotes, dont on peut détecter les zones d'accumulation dans le noyau grâce à son affinité pour certains colorants basiques, notamment le colorant de Feulgen. 2, record 9, French, - chromatine
Record number: 9, Textual support number: 1 OBS
Elle correspond à l'association de macromolécules d'acide désoxyribonucléique avec un type particulier de protéines basiques, appelées histones. L'association s'établit grâce à la troisième fonction acide des radicaux phosphoriques de l'ADN. 2, record 9, French, - chromatine
Record 9, Spanish
Record 9, Campo(s) temático(s)
- Genética
Record 9, Main entry term, Spanish
- cromatina
1, record 9, Spanish, cromatina
correct, feminine noun
Record 9, Abbreviations, Spanish
Record 9, Synonyms, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 1996-10-23
Record 10, English
Record 10, Subject field(s)
- Genetics
Record 10, Main entry term, English
- orphon
1, record 10, English, orphon
correct
Record 10, Abbreviations, English
Record 10, Synonyms, English
Record 10, Textual support, English
Record number: 10, Textual support number: 1 DEF
A dispersed, single pseudogene derived from tandemly repeated families or gene clusters, such as those for histones or hemoglobins. Orphons may serve as a reservoir of sequences which can evolve new functions, and have probably been important factors in the evolution of higher organisms. 2, record 10, English, - orphon
Record 10, French
Record 10, Domaine(s)
- Génétique
Record 10, Main entry term, French
- orphon
1, record 10, French, orphon
correct, masculine noun
Record 10, Abbreviations, French
Record 10, Synonyms, French
Record 10, Textual support, French
Record number: 10, Textual support number: 1 DEF
Élément génétique solitaire qui dérive d'une famille multigénique organisée en tandem. 1, record 10, French, - orphon
Record 10, Spanish
Record 10, Textual support, Spanish
Record 11 - internal organization data 1990-02-26
Record 11, English
Record 11, Subject field(s)
- Genetics
Record 11, Main entry term, English
- histones
1, record 11, English, histones
correct
Record 11, Abbreviations, English
Record 11, Synonyms, English
Record 11, Textual support, English
Record number: 11, Textual support number: 1 DEF
A group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They contain a large proportion of the basic (positively charged) amino acids lysine, arginine, and histidine. They are believed to be involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. 1, record 11, English, - histones
Record 11, French
Record 11, Domaine(s)
- Génétique
Record 11, Main entry term, French
- histones
1, record 11, French, histones
correct, feminine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
Record 11, Textual support, French
Record number: 11, Textual support number: 1 DEF
Classe de protéines basiques (contenant beaucoup d'arginine et de lysine, acides aminés basiques) associées avec l'ADN. Celui-ci, déjà superenroulé, s'embobine autour d'elles pour augmenter son compactage, en formant des structures appelées nucléosomes. 1, record 11, French, - histones
Record 11, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 1989-09-05
Record 12, English
Record 12, Subject field(s)
- Cytology
Record 12, Main entry term, English
- nuclear pore
1, record 12, English, nuclear%20pore
correct
Record 12, Abbreviations, English
Record 12, Synonyms, English
Record 12, Textual support, English
Record number: 12, Textual support number: 1 DEF
an annular-shaped hole that occurs in the nuclear membrane; usually large numbers are present. The inner and outer membranes of the nucleus become fused together at the annulus.(They) are the site of active transport of materials into and out of the nucleus. Nuclear imports include the nucleotide precursors of DNA and RNA, histones and ribosomal proteins, whereas exports include mRNA, tRNA and ribosomal subunits. 2, record 12, English, - nuclear%20pore
Record 12, French
Record 12, Domaine(s)
- Cytologie
Record 12, Main entry term, French
- pore nucléaire
1, record 12, French, pore%20nucl%C3%A9aire
correct, masculine noun
Record 12, Abbreviations, French
Record 12, Synonyms, French
Record 12, Textual support, French
Record number: 12, Textual support number: 1 DEF
structure complexe de l'enveloppe nucléaire. À son niveau, les deux membranes, externe et interne, de l'enveloppe se rejoignent et s'accolent. Les pores sont distribués régulièrement et en nombre proportionnel à l'activité de la cellule. Chaque pore comprend un matériel annulaire constitué par des fibrilles pelotonnées sur elles-mêmes. Un granule central qui serait une ribonucléoprotéine et un diaphragme. 2, record 12, French, - pore%20nucl%C3%A9aire
Record 12, Spanish
Record 12, Textual support, Spanish
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