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HIT LEAD [6 records]

Record 1 2022-05-02

English

Subject field(s)
  • Pharmacology
  • Biotechnology
CONT

Lead generation, also referred to as hit to lead phase, involves optimization of the identified hits from a diverse series to generate lead compounds.

Key term(s)
  • H2L phase
  • H2L

French

Domaine(s)
  • Pharmacologie
  • Biotechnologie

Spanish

Save record 1

Record 2 2015-12-24

English

Subject field(s)
  • Printing Machines and Equipment
CONT

Clean and lubricate your delivery chains to ensure longevity of the chain. You may notice sheets marking at the lead edge due to the stretching of the chains. If your machine shuts off for no seen reason, you probably have a stretched delivery chain, which causes the sheet to hit sensors at higher speeds.

French

Domaine(s)
  • Équipement (Imprimerie et arts graphiques)
CONT

[...] suppression de l’étape «Film» dans la chaîne de sortie des pages, insolation automatique des plaques, réduction du nombre de plaques à insoler grâce à la technologie simple développement [...]

Spanish

Save record 2

Record 3 2011-11-25

English

Subject field(s)
  • Weapon Systems (Land Forces)
  • Target Acquisition
CONT

... the gun barrels are fitted with muzzle velocity sensors, which are linked to the fire control computer, so the actual speed of the round can be taken into account when the computer calculates the lead angle necessary to hit a moving target. This is necessary as the speed of the round when leaving the barrel may vary depending on the ammunition manufacture date and age, moisture content, the barrel wear, etc.

CONT

Projectile muzzle velocity sensor mounted on T-84 MBT [main battle tank] turret roof. As an option, the tank fire-control system can also include a projectile muzzle velocity sensor, which measures the velocity in question and feeds information to the tank’s fire control ballistic computer after each firing of the gun to allow to automatically correct for gun bore wear, charge temperature and other factors.

French

Domaine(s)
  • Systèmes d'armes (Forces terrestres)
  • Acquisition d'objectif

Spanish

Save record 3

Record 4 2010-11-08

English

Subject field(s)
  • North American Football
CONT

Peter Benoite scored 12 points for the Outlaws who trailed until late in the fourth quarter when seldom seen quarterback Chris Wheeler hit Dave Rouah on a deep out pattern to take a 31-27 lead.

French

Domaine(s)
  • Football nord-américain

Spanish

Save record 4

Record 5 2004-06-07

English

Subject field(s)
  • Track and Field
  • Physical Education, Coaching and Sport Psychology
  • Physical Fitness Training and Bodybuilding
DEF

A psychological or physical barrier, a feeling of exhaustion, which a runner, a cyclist, a cross-country skier or any long-distance performer may experience during a race (especially a marathon).

CONT

"The Wall. "It evades easy definition, but to borrow from Supreme Court Justice Potter Stewart's famous definition of obscenity, you know it when you see it-or rather, hit it. It usually happens around mile 20, give or take a couple of miles. Your pace slows, sometimes considerably. Some runners say that it feels as though their legs had been filled with lead quail shot... Others can’t feel their feet at all. Thought processes become a little fuzzy... Muscle coordination goes out the window, and self-doubt casts a deep shadow over the soul.... Even if you’re racing at a reasonable pace and you’ve done a good job of carboloading in the days before the marathon, you still have only about 2, 000 calories worth of glycogen stored in the muscles and liver; that's about enough to get you to-surprise!-mile 20. If you manage to deplete your glycogen reserves, say hello to The Wall.

CONT

It is this depletion of muscle glycogen that sportspeople know as "hitting the wall."

CONT

The bad news is that more than half of all nonelite marathon runners report having hit The Wall at least once. The good news is that more than 40 percent of all nonelite marathon runners have never hit The Wall. In other words, while it certainly doesn’t hurt to be prepared for the possibility of hitting The Wall, doing so is far from inevitable.

OBS

wall: something that resembles a wall in function especially by establishing limits.

PHR

Runner wall.

French

Domaine(s)
  • Athlétisme
  • Éducation physique, entraînement des athlètes et psychologie du sport
  • Conditionnement physique et culturisme
CONT

La soudaineté de la fatigue en course sur route et au marathon en particulier a conduit à l'expression désormais classique : «frapper le mur». [...] En fait, il n'y a pas un mur mais des murs. [...] Le premier est «la panne de glycogène musculaire». Le deuxième est «la panne de glucose sanguin». Le troisième est «le mur de la chaleur».

OBS

Le «mur de la chaleur» guette tous les coureurs si les conditions atmosphériques ne sont pas favorables : c'est-à-dire s'il fait trop chaud, s'il y a trop de soleil ou s'il fait trop humide. Il guette aussi les coureurs qui ne boivent pas suffisamment pendant la course. N'oubliez donc pas de boire.

OBS

Au Canada, «frapper le mur» veut dire souffrir des effets de l'un ou l'autre des 3 murs. En France, «toucher le mur» veut dire être victime de la panne de glycogène musculaire.

PHR

Mur de la chaleur; frapper le mur.

PHR

Toucher le mur.

Spanish

Save record 5

Record 6 1987-06-30

English

Subject field(s)
  • Small Arms
CONT

... rapid semi-automatic fire can put a lethal amount of lead in the air with more chance of hit than a three-round burst...

French

Domaine(s)
  • Armes légères
CONT

(...) le tir rapide en mode semi-automatique offre, vu le nombre de projectiles qui traversent les airs, une meilleure probabilité d'atteinte qu'une rafale de trois coups (...)

Spanish

Save record 6

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