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HIV POL GENE [2 records]
Record 1 - internal organization data 2011-11-02
Record 1, English
Record 1, Subject field(s)
- Microbiology and Parasitology
- Cytology
- Biochemistry
Record 1, Main entry term, English
- pol gene
1, record 1, English, pol%20gene
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- pol 1, record 1, English, pol
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The HIV gene which codes for polymerase enzyme. 2, record 1, English, - pol%20gene
Record number: 1, Textual support number: 1 OBS
The pol gene encodes the reverse transcriptase enzyme(p53, p66), which transcribes viral RNA into DNA, a step required before HIV viral proteins and new viruses can be made. Also encoded in the pol gene are a portion of the HIV protease(5’end) and an endonuclease protein(p31). 3, record 1, English, - pol%20gene
Record number: 1, Textual support number: 2 OBS
pol: polymerase (reverse transcriptase). 3, record 1, English, - pol%20gene
Record 1, Key term(s)
- polymerase
- polymerase gene
- HIV pol gene
- HIV polymerase gene
Record 1, French
Record 1, Domaine(s)
- Microbiologie et parasitologie
- Cytologie
- Biochimie
Record 1, Main entry term, French
- gène pol
1, record 1, French, g%C3%A8ne%20pol
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- pol 1, record 1, French, pol
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les gènes du V.I.H.-1 comportent les trois gènes structuraux fondamentaux des rétrovirus, présents à la fois dans les cellules infectées et dans les particules virales matures. Le gène gag (ce qui signifie gène de l'antigène de groupe) qui code pour les protéines de nucléotide; le gène pol (pour polymérase) qui détermine la synthèse de l'enzyme caractéristique des rétrovirus, la transcriptase inverse (ou reverse transcriptase); à son extrémité existe un petit gène qui code pour une protéase dont le rôle est de cliver les protéines produites par le gène gag; le gène env (pour enveloppe) qui permet la synthèse des glycoprotéines de l'enveloppe virale. 2, record 1, French, - g%C3%A8ne%20pol
Record 1, Key term(s)
- polymérase
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Microbiología y parasitología
- Citología
- Bioquímica
Record 1, Main entry term, Spanish
- gen pol
1, record 1, Spanish, gen%20pol
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- pol 1, record 1, Spanish, pol
correct, masculine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Gen viral que sintetiza la polimerasa o transcriptasa reversa de los retrovirus. 1, record 1, Spanish, - gen%20pol
Record 2 - internal organization data 2011-06-10
Record 2, English
Record 2, Subject field(s)
- Microbiology and Parasitology
- Biotechnology
Record 2, Main entry term, English
- viral protein
1, record 2, English, viral%20protein
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
The human immunodeficiency virus(HIV) genome encodes at least seven groups of viral proteins. These groups of proteins include the three classes of polypeptides present in the majority of animal retroviruses : 1. structural, nonenvelope polypeptides encoded by the gag gene; 2. enzymes required for virion replication(reverse transcriptase/r) and for cleavage of viral precursor proteins(protease/pr), both encoded by the pol gene; 3. envelope polypeptides encoded by env gene. In addition, HIV's possess genes that encode four sets of polypeptides not found in the majority of typical retroviruses. These include a transactivating regulator of RNA translation(tat), a cis-acting downregulator of RNA transcription(nef), a regulator that modulates the expression of structural proteins(rev), a protein that modulates viral infectivity(vif), and two proteins(vpr, vpu) whose functions are still unclear. [From source a]. 2, record 2, English, - viral%20protein
Record number: 2, Textual support number: 1 OBS
Both the core and envelope of HIV are composed of viral proteins. The core viral proteins include p24 and p18, and the envelope viral proteins include gp41 and gp120. 3, record 2, English, - viral%20protein
Record 2, French
Record 2, Domaine(s)
- Microbiologie et parasitologie
- Biotechnologie
Record 2, Main entry term, French
- protéine virale
1, record 2, French, prot%C3%A9ine%20virale
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Protéines virales. Les protéines du V.I.H.-1, toutes antigéniques, c'est-à-dire capables d'induire la production d'anticorps, se répartissent en : 1) Des protéines associées à la nucléocapside. Ce sont des protéines structurales internes liées aux unités d'ARN et formant avec elle la nucléoïde. 2) Des protéines d'enveloppes chargées de sucres (glycoprotéines) 3) De nombreuses autres protéines identifiées récemment et dont le rôle commence à être connu. 2, record 2, French, - prot%C3%A9ine%20virale
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Microbiología y parasitología
- Biotecnología
Record 2, Main entry term, Spanish
- proteína viral
1, record 2, Spanish, prote%C3%ADna%20viral
correct, feminine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
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