TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 OBS

The Canadian HIV [human immunodeficiency virus] Vaccine Initiative [is] a collaboration between the Government of Canada and the Bill & Melinda Gates Foundation... The initiative is intended to contribute to the global effort to develop safe, effective, affordable and globally accessible HIV vaccines.  3, record 1, English, - Canadian%20HIV%20Vaccine%20Initiative

Record number: 1, Textual support number: 2 OBS

HIV: human immunodeficiency virus.  4, record 1, English, - Canadian%20HIV%20Vaccine%20Initiative

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 OBS

L'Initiative canadienne de vaccin contre le VIH [virus de l'immunodéficience humaine] est le fruit d'une collaboration entre le gouvernement du Canada [...] et la Fondation Bill & Melinda Gates [...] Cette initiative représente le concours du Canada aux efforts mondiaux visant à élaborer un vaccin contre le VIH qui soit sécuritaire, efficace, abordable et accessible partout dans le monde.  3, record 1, French, - Initiative%20canadienne%20de%20vaccin%20contre%20le%20VIH

Record number: 1, Textual support number: 2 OBS

VIH : virus de l'immunodéficience humaine.  4, record 1, French, - Initiative%20canadienne%20de%20vaccin%20contre%20le%20VIH

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 OBS

VIH: virus de inmunodeficiencia humana causante del sida.  2, record 1, Spanish, - Iniciativa%20Canadiense%20de%20Vacuna%20contra%20el%20VIH

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

For a viral vector vaccine, non-HIV [human immunodeficiency virus] viruses are used to carry genes that tell the body to make some HIV proteins. These viral vectors don’t cause disease in people. The genes are inserted into the vector, which carries them into the body's cells.  3, record 2, English, - viral%20vector%20vaccine

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Les vaccins à vecteurs viraux sont obtenus en insérant les gènes codant l'antigène d'un agent infectieux dans un vecteur viral non pathogène [...]  3, record 2, French, - vaccin%20%C3%A0%20vecteur%20viral

Record 2,  Textual support,  Spanish

Record number: 2, Textual support number: 1 DEF

[...] vacuna que utiliza [una versión modificada de un virus como vector,] para introducir material genético que codifica un antígeno deseado, en las células del sujeto que la recibe.  1, record 2, Spanish, - vacuna%20de%20vector%20viral

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

A strain of HIV used in vaccine development.  1, record 3, English, - SF%2D2

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

[...] l'état du système immunitaire et le niveau de réplication virale semblent jouer un rôle important dans la réponse à la vaccination. Dans les essais ACTG 209 et 214, les sujets infectés (50-500 T CD4/mul, non traités ou recevant une mono- ou bithérapie d'inhibiteurs nucléosidiques à l'entrée de l'étude) ont reçu l'un des 4 vaccins protéiques d'enveloppe suivants gp120-MN, ou IIIB (Genentech) ou rgp120 SF-2 ou Env2-3 (Chiron).  1, record 3, French, - SF%2D2

Record number: 3, Textual support number: 2 CONT

[...] avec certains candidats vaccins, la réactivité des anticorps neutralisants était élargie non seulement contre la souche ayant servi à fabriquer le vaccin (souche MN, SF", IIIB, ...) mais contre d'autres souches.  3, record 3, French, - SF%2D2

Record number: 3, Textual support number: 3 CONT

Les souches de virus dont on a exprimé les glycoprotéines sont les souches LAI, MN ou SF2, toutes trois de sous-type B.  4, record 3, French, - SF%2D2

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

The science of AIDS and its impact on the developing world. In 1995, AIDS research stands at a crossroads. Over the past 10 years, much of the research on AIDS has centred on trying to find a cure or a vaccine, with very limited results. While more has been learnt about AIDS in a short time than about almost any other disease, many of the basic questions about the development of AIDS and the behaviour of HIV, the virus which leads to AIDS, remain unanswered.  1, record 4, English, - science%20of%20aids

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Discipline qui étudie le sida; elle est exercée par des sidénologues.  2, record 4, French, - sid%C3%A9nologie

Record number: 4, Textual support number: 1 CONT

Le Xème Symposium de Sidénologie du 17 au 19 juin 1999 à Toulon réunissait des spécialistes VIH, dont quelques-uns de renommée mondiale comme David Ho, Robert Gallo (USA) et Julio Montaner (Canada).  3, record 4, French, - sid%C3%A9nologie

Record 4,  Textual support,  Spanish

Record number: 4, Textual support number: 1 OBS

Las siglas del síndrome de inmunodeficiencia adquirida (sida) se han incorporado al español como un nombre común, por lo cual se escriben en minúsculas, no obstante, se escriben también con mayúsculas.  2, record 4, Spanish, - ciencia%20del%20SIDA

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

An attenuated strain of Mycobacterium bovis.  2, record 5, English, - bacille%20Calmette%2DGu%C3%A9rin

Record number: 5, Textual support number: 1 OBS

BCG is used in some countries as a vaccine against tuberculosis.... BCG adenitis is an illness caused by BCG that is present in some infants with HIV and is characterized by inflammation of the lymph nodes.  2, record 5, English, - bacille%20Calmette%2DGu%C3%A9rin

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

Le vaccin antituberculeux est le seul vaccin bactérien constitué de bactéries vivantes atténuées. Il a été mis au point par Calmette et Guérin (d'où les initiales de BCG : bacille de Calmette et Guérin) entre 1908 et 1921, à partir de bacilles atténués d'origine bovine.  1, record 5, French, - bacille%20de%20Calmette%20et%20Gu%C3%A9rin

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 OBS

Adopted at the 1st meeting of the Steering Committee on HIV Vaccine Development in May 1991; in reference to the preventive, therapeutic and perinatal HIV vaccines; WHO [World Health Organization].  1, record 6, English, - WHO%20Strategy%20for%20AIDS%20Vaccine%20Development

Record 6,  Textual support,  French

Record 6,  Textual support,  Spanish

Record number: 6, Textual support number: 1 OBS

Las siglas del síndrome de inmunodeficiencia adquirida (sida) se han incorporado al español como un nombre común, por lo cual se escriben en minúsculas.  2, record 6, Spanish, - Estrategia%20OMS%20de%20desarrollo%20de%20vacunas%20contra%20el%20SIDA

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

vaccines : Vaccines are being tested as treatments for people who are HIV+. From all studies conducted to date, HIV vaccines appear to be safe in HIV+ people. At this time it is not known if they are effective treatments. The vaccine cannot give you HIV  1, record 7, English, - HIV%20vaccine

Record 7,  Textual support,  French

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 OBS

[Actualmente], se trabaja en cinco tipos de estrategias para la elaboración de una vacuna contra el VIH: subunidades recombinantes, péptidos sintéticos, vectores virales, antiidiotipos y virus (que pueden ser atenuados, muertos o fragmentados).  1, record 7, Spanish, - vacuna%20contra%20el%20VIH

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

There are two types of HIV :HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States. HIV-2, seen more often in western Africa, has a slower course than HIV-1. There are many strains of both types and the virus mutates rapidly, a trait that has made it especially difficult for researchers to find an effective treatment or vaccine.  1, record 8, English, - VIH%2D2

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

En 1985, a été découverte une seconde forme de virus [VIH1], le VIH2 présente surtout en Afrique Orientale.  1, record 8, French, - VIH2

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  French

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 CONT

Therapeutic vaccination while the virus is well suppressed with antiretrovirals. In one study, first reported last summer at Geneva and with new data last week at the Retroviruses conference, volunteers whose viral load had been effectively suppressed with antiretrovirals were also given a killed-virus immunogen(the Remune(TM) therapeutic vaccine, which was developed by the late Dr. Jonas Salk) ;a control group was given the inactive component of the same vaccine but without the HIV. T-helper responses like those of long-term nonprogressors returned in most of those given the real vaccine--and in none of the control group.  1, record 10, English, - therapeutic%20vaccination

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 CONT

L'idée de stimuler le système immunitaire pour s'opposer à la multiplication des cellules cancéreuses date des travaux de l'allemand Paul Ehrlich, au début du siècle [...]Mais ce n'est que vers les années quatre-vingt que le concept a commencé à être mis en pratique avec des méthodes modernes chez l'homme par injection de cytokines telles que l'interleulike 2 et l'interféron alpha, puis par introduction des gènes codant ces molécules dans les cellules cancéreuses, et dernièrement par «vaccination thérapeutique», une immunothérapie qui cherche à induire des réponses immunitaires cytotoxiques et mémorisables, contre les antigènes portés par les cellules tumorales.  1, record 10, French, - vaccination%20th%C3%A9rapeutique

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  French

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 CONT

As well, we are continuing to explore a new approach to subunit vaccine design introduced by our laboratory a number of years ago(see Carayanniotis and Barber(1987) Nature 327, 59). By conjugation of purified protein or synthetic peptide antigens to monoclonal antibodies specific for defined cell surface determinants in vivo(e. g. class II MHC), it is possible to induce an effective antibody response to the "targeted" antigen(for recent data see Skea and Barber(1993) J. Immunol. 151, 3557). We are currently using recombinant DNA approaches to "engineer" specific B-and T-cell epitopes into selected sites on immunotargeting antibodies. In addition to our work using influenza virus as a model, we are also studying conserved B-and T-cell epitopes from HIV in order to develop a candidate AIDS vaccine.  2, record 12, English, - immunotargeting

Record 12,  Textual support,  French

Record 12,  Textual support,  Spanish