TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Homologous recombination is that which we are taught about in introductory biology class. It is the crossing-over process observed during meiosis, though it occurs in bacteria as well. The process involves pairing up of similar DNA sequences, with then one sequence replacing the other, or indeed for meiotic crossing over, with the generation of now two recombinant strands, one for each chromosome homolog, rather than just one. In either case, key is that it is DNA that is highly similar in terms of DNA sequence that is being either replaced or swapped. This allows for a replacement of alleles following horizontal gene transfer, or allele swapping...  2, record 1, English, - homologous%20recombination

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Recombinaison qui s'effectue par échange de segments d'ADN entre deux séquences identiques ou proches.  2, record 1, French, - recombinaison%20homologue

Record number: 1, Textual support number: 1 OBS

La recombinaison homologue intervient notamment dans la recombinaison génétique au cours de la méiose.  2, record 1, French, - recombinaison%20homologue

Record number: 1, Textual support number: 1 CONT

recombinaison homologue : désignation et définition publiées au Journal officiel de la République française le 4 février 2021.  3, record 1, French, - recombinaison%20homologue

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Intercambio de fragmentos de ADN entre las dos cromátidas no hermanas del mismo cromosoma durante la meiosis.  1, record 1, Spanish, - recombinaci%C3%B3n%20hom%C3%B3loga

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

Morphologically conspicuous chromosome that can regularly be distinguished from its homologous partner.  1, record 2, English, - marker%20chromosome

Record number: 2, Textual support number: 1 CONT

A marker chromosome of completely unknown origin should be designated by the original Chicago Conference symbol mar.  1, record 2, English, - marker%20chromosome

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Chromosome ayant une forme qui frappe l'œil et que l'on peut facilement distinguer de son partenaire homologue.  1, record 2, French, - chromosome%20marqueur

Record number: 2, Textual support number: 1 CONT

Un chromosome marqueur d'origine inconnue, peut être désigné par le symbole mar.  1, record 2, French, - chromosome%20marqueur

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

Any two chromosomes that undergo pairing during the prophase of meiosis. They are very similar in length and shape, have centromeres at the same point, and contain the same gene loci. They occur in all diploid organisms and their presence infers that two copies of each gene occur in each cell, although these copies may differ in being allelic forms of the same sequence.  2, record 3, English, - homologous%20chromosome

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 OBS

Qualifie chacun des deux chromosomes d'une même paire dans une cellule diploïde.  2, record 3, French, - chromosome%20homologue

Record number: 3, Textual support number: 2 OBS

Quand il s'agit de gènes, on parle de préférence de gènes allèles car la notion d'allélisme est plus complexe, en particulier dans les cas de polyallélie.  2, record 3, French, - chromosome%20homologue

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

An unpaired loop formed by a deletion in a heterozygote containing paired homologous polytene chromosomes. The deletion causes the normal, nondeleted chromosome to form an unpaired loop opposite the deleted segment.  1, record 4, English, - deletion%20loop

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Boucle formée lors de l'appariement méiotique chez un organisme hétérozygote pour un chromosome normal et un chromosome porteur d'une délétion. Presque toutes les délétions sont létales à l'état homozygote; les délétions importantes peuvent même l'être à l'état hétérozygote.  2, record 4, French, - boucle%20de%20d%C3%A9l%C3%A9tion

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

Recombination between specific pairs of sequences. It is responsible for the integration of phage genomes into the bacterial chromosome. The recombination event involves a specific sequence of the phage DNA and a specific sequence of the bacterial DNA. Within these sequences, there is only a short stretch of homology, necessary for the recombination event, but not sufficient for it. The enzymes involved in this event cannot recombine other pairs of(homologous or nonhomologous) sequences, but act only on the particular pair of phage and bacterial sequences.  2, record 5, English, - site%2Dspecific%20recombination

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Recombinaison de fragments cohésifs d'ADN engendrés par des coupures nucléasiques à des sites très spécifiques. Un exemple est l'insertion d'une molécule circulaire d'ADN de lambda dans le site récepteur du chromosome d'E. coli.  2, record 5, French, - recombinaison%20%C3%A0%20des%20sites%20sp%C3%A9cifiques

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

[Referring to] chromosome complements, cells or organisms with more than 2 sets of homologous chromosomes.  2, record 6, English, - autopolyploid

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 DEF

Dont les génomes, en nombre supérieur à deux, proviennent de la même espèce.  3, record 6, French, - autopolyplo%C3%AFde

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

The complementary action of different genetic factors.  2, record 7, English, - complementation

Record number: 7, Textual support number: 1 OBS

The term usually implies two homologous chromosomes or chromosome sets, each defective because of mutation and unable by itself to promote the normal development or metabolism of the organism, but able to do so jointly when brought together in the same cell.  2, record 7, English, - complementation

Record 7,  Textual support,  French

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 DEF

Situación que se produce cuando dos moléculas de ADN [ácido desoxirribonucleico] en la misma célula producen juntas una función que ninguna de ellas podría realizar por sí sola.  2, record 7, Spanish, - complementaci%C3%B3n

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

During the normal production of sperm and egg cells, DNA strands occasionally break and rejoin in different places on the same chromosome or on the other copy of the same chromosome(i. e., the homologous chromosome). This process(called meiotic recombination) can result in the separation of two markers orginally on the same chromosome.  1, record 8, English, - meiotic%20recombination

Record number: 8, Textual support number: 2 CONT

A genetic linkage map shows the relative locations of specific DNA markers along the chromosome. Any inherited physical or molecular characteristic that differs among individuals and is easily detectable in the laboratory is a potential genetic marker.  1, record 8, English, - meiotic%20recombination

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

Nos travaux concernent l'étude des sites d'initiation et la caractérisation des lésions initiatrices. Il s'agit de cassures double-brin de l'ADN (CDBs) dont la réparation sur le chromosome homologue conduit à la recombinaison méiotique, qui est une étape nécessaire à la ségrégation réductionnelle des chromosomes homologues lors de la 1ère division de méiose.  1, record 8, French, - recombinaison%20m%C3%A9iotique

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 DEF

A unit of chromatin stained by the C-staining methods i. e., methods which demonstrate "constitutive heterochromatin"(i. e., the heterochromatin generally present in homologous chromosome regions).  1, record 9, English, - C%2Dband

Record number: 9, Textual support number: 1 CONT

The c-bands on chromosomes Nos 1, 9 and 16 and the large distal band on the Yq are all associated with obvious morphologic variability.  2, record 9, English, - C%2Dband

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 DEF

Unité de chromatine colorée par les méthodes de coloration C, c'est-à-dire celles qui mettent en évidence «l'hétérochromatine constitutive».  1, record 9, French, - bande%20C

Record number: 9, Textual support number: 1 CONT

D'autres techniques sont utilisées dans des buts particuliers. Bandes C : coloration des centromères.  1, record 9, French, - bande%20C

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 DEF

Pattern formed by three homologous chromosomes, after their partial opening and the joining of the corresponding segments. This phenomenon occurs at the zygotene or pachytene stages and is reversible.  2, record 10, English, - trivalent

Record number: 10, Textual support number: 1 CONT

(Chromosome mutation) The three homologous chromosomes in the trisomic parent may pair in a variety of ways forming either a bivalent and a univalent, or a trivalent or they may fail to pair so that three univalents are formed.  2, record 10, English, - trivalent

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 DEF

Figure formée par trois chromosomes homologues, après leur ouverture partielle et l'accolement des segments correspondants. Ce phénomène apparaît aux stades zygotène et pachytène, et est réversible.  2, record 10, French, - trivalent

Record number: 10, Textual support number: 1 CONT

Cette trisomie morphologiquement très probable, est d'autre part confirmée par l'existence de trivalents à la méiose chez les trisomiques 21 [...]  2, record 10, French, - trivalent

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 DEF

Any chromosome other than the sex chromosomes. These occur in homologous pairs in diploid cells.  4, record 11, English, - autosome

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 DEF

Chromosome présent dans les cellules somatiques comme dans les gamètes et dont les informations génétiques n'interviennent pas dans la détermination du sexe (par opposition aux gonosomes). Dans les cellules somatiques, ils existent sous forme de paires homologues l'un étant d'origine paternelle, l'autre d'origine maternelle. (D'après MEDEC, 1985, p. 91).  2, record 11, French, - autosome

Record 11,  Textual support,  Spanish

Record number: 11, Textual support number: 1 DEF

Cromosoma no sexual.  1, record 11, Spanish, - autosoma

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 DEF

Having or being a diploid chromosome complement in which one or more than one pair of homologous chromosomes is lacking. Hence as n., a nullisomic individual.  2, record 12, English, - nullisomic

Record 12,  Textual support,  French

Record number: 12, Textual support number: 1 DEF

Cellule ou organisme dont le complément chromosomique a perdu deux membres de l'une des paires chromosomiques du complément normal.  2, record 12, French, - nullisomique

Record 12,  Textual support,  Spanish

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 DEF

In meiotic cells, a protein with broad phyletic distribution and unique cellular localization which shows a high binding efficiency for single-stranded DNA and the property of catalyzing the renaturation of thermally denatured DNA. The protein is assumed to play a role in meiotic recombination and to promote chromosome pairing and crossing over between homologous chromosomes. It is absent from somatic tissues.  1, record 13, English, - DNA%2Dbinding%20protein

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 CONT

Le déroulement des deux biens de la molécule de DNA entraîne la formation de zones monocoténaires. Ces zones simple brin doivent être stabilisées (suppression du réappariement des deux brins de la molécule de DNA) et protégées de l'action des DNases. Ces fonctions semblent être assurées par une protéine appelée «DNA binding protein» qui se lie spécifiquement au DNA simple chaîne [...]. C'est le complexe formé par l'association entre le DNA monocoténaire et la protéine de liaison au DNA qui constitue en fait le substrat de la DNA polymérase III et des autres protéines qui jouent un rôle dans la réplication.  1, record 13, French, - prot%C3%A9ine%20de%20liaison%20au%20DNA

Record number: 13, Textual support number: 2 CONT

La régulation de l'expression d'un gène passe, entre autres mécanismes, par l'association de protéines à certaines des séquences d'acides nucléiques qui le constituent. L'analyse de ces séquences et celles des protéines régulatrices qui s'y fixent est donc d'une importance capitale pour la compréhension des mécanismes de régulation de l'expression des gènes.  2, record 13, French, - prot%C3%A9ine%20de%20liaison%20au%20DNA

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 DEF

In meiosis, the stage following synapsis in which the homologous chromosome threads shorten, thicken, and intertwine.  2, record 14, English, - pachytene

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Troisième stade de la première division méiotique où les 2 chromosomes homologues accolés apparaissent sous forme de bivalents. (FLAME)  1, record 14, French, - stade%20pachyt%C3%A8ne

Record number: 14, Textual support number: 1 CONT

Dès la phase zygotène de la prophase 1 (synapsis), les deux chromosomes X homologues (paternel et maternel) s'apparient et s'accolent suivant leur longueur. Cet accolement forme donc un bivalent qui, à la phase suivante (pachytène) va se raccourcir et s'épaissir. (ESSE Vol. 14, 3, 1977, p. 2)  1, record 14, French, - stade%20pachyt%C3%A8ne

Record 14,  Textual support,  Spanish

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 DEF

A mediocentric chromosome with homologous arms, probably resulting from an abnormal transverse division of the centromere during meiosis.  2, record 15, English, - isochromosome

Record 15,  Textual support,  French

Record number: 15, Textual support number: 1 DEF

Chromosome anormal résultant d'une division transversale du centromère et dont les deux bras sont d'égale longueur.  2, record 15, French, - isochromosome

Record 15,  Textual support,  Spanish

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 DEF

That portion of the original chromosome of a merozygote that is homologous to the exogenote.(KIDIG)  2, record 16, English, - endogenote

Record number: 16, Textual support number: 1 CONT

Names have also been coined to denote the components of a heterogenote, the immigrant fragment of donor chromosome being termed an exogenote, and the recipient chromosome an endogenote. (HAGEB p. 628)  2, record 16, English, - endogenote

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 DEF

Dans les processus parasexués des bactéries, la partie du matériel génétique de la bactérie réceptrice qui est homologue du segment d'acide désoxyribonucléique appelé exogénote, qui est transféré de la bactérie donatrice à la bactérie réceptrice. (HEDGE)  2, record 16, French, - endogenote

Record number: 16, Textual support number: 1 CONT

Ce facteur F' apparemment alterne rapidement entre l'insertion et la désinsertion chromonémique et ce à cause des possibilités d'appariement et de recombinaisons entre les régions alléliques de l'exogénote et de l'endogénote. (LISYL p. 2.56)  2, record 16, French, - endogenote

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 DEF

[Of or having to do with] changes of chromosome structure in which the arms of homologous chromosomes are included.  2, record 17, English, - allelobrachial

Record 17,  Textual support,  French

Record 17,  Textual support,  Spanish

Record 18,  Textual support,  English

Record number: 18, Textual support number: 1 CONT

In a polyploid derivative of an interspecific hybrid each parental chromosome is represented twice(amphidiploid) or one genome occurs twice and the other only once(sesquidiploid). So there is a choice of pairing between homologous chromosomes(autosyndesis) or homologous chromosomes(allosyndesis). For estimating the amount of allosyndesis in a polyploid derivative of an interspecific hybrid, allosyndetic bivalents should also be taken into consideration in addition to multivalents.  2, record 18, English, - allosyndesis

Record 18,  Textual support,  French

Record number: 18, Textual support number: 1 DEF

À la méiose d'un hybride entre deux espèces polyploïdes, appariement entre les chromosomes de ces deux espèces.  1, record 18, French, - allosynd%C3%A8se

Record 18,  Textual support,  Spanish

Record 19,  Textual support,  English

Record number: 19, Textual support number: 1 DEF

the chromosomes of a matching pair in the diploid complement that contains the alleles of specific genes.  1, record 19, English, - homologous%20chromosome

Record 19,  Textual support,  French

Record number: 19, Textual support number: 1 OBS

Les chromosomes homologues provenant d'un gamète parental différent (ou de progéniture différent) ont la propriété de s'échanger du matériel génétique à une certaine étape de la méiose.  2, record 19, French, - chromosome%20homologue

Record 19,  Textual support,  Spanish

Record 20,  Textual support,  English

Record number: 20, Textual support number: 1 CONT

One short-term goal of the genome project is to develop a high-resolution genetic map(2 to 5_cM) ;recent consensus maps of some chromosome have averaged 7 to 10_cM between genetic markers. e., the homologous chromosome) This process(called meiotic recombination) can result in the separation of two markers orginally on the same chromosome.  1, record 20, English, - high%2Dresolution%20genetic%20map

Record 20,  Textual support,  French

Record 20,  Textual support,  Spanish

Record 21,  Textual support,  English

Record number: 21, Textual support number: 1 CONT

In the ideal world, the diseases would be cured for life by one treatment, with no side effects. And gene insertion into a chromosome in a target somatic cell would be site specific; in what is called homologous recombination, the healthy, or "therapeutic, "gene would exactly replace the damaged copy  1, record 21, English, - therapeutic%20gene

Record 21,  Textual support,  French

Record number: 21, Textual support number: 1 CONT

Des gènes marqueurs aux gènes thérapeutiques. De nombreux participants ont manifesté la volonté d'utiliser des approches de marquage avant d'aborder le problème du transfert génique en vue d'une action thérapeutique.  2, record 21, French, - g%C3%A8ne%20th%C3%A9rapeutique

Record 21,  Textual support,  Spanish

Record 22,  Textual support,  English

Record number: 22, Textual support number: 1 CONT

The pairing of the homologous chromosomes in the preliminary prophase of meiosis divides the number of chromosomes in half; a pair of homologues behaves as one chromosome. Each homologue has replicated before the pairing; after pairing, the chromosomes are bivalents, structures consisting of two parts(homologues), each of which is a pair of sister chromosome strands.  2, record 22, English, - pairing

Record 22,  Textual support,  French

Record number: 22, Textual support number: 1 DEF

Phénomène qui, au cours de la méiose, consiste en le rapprochement des chromosomes homologues.  3, record 22, French, - appariement

Record number: 22, Textual support number: 1 CONT

[Le] stade zygotène [...] est caractérisé par l'appariement des chromosomes homologues de chaque paire, ou synapsis. Un tel appariement est un fait nouveau qui ne se produit pas dans une mitose normale.  4, record 22, French, - appariement

Record 22,  Textual support,  Spanish