TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

[A] large pentameric immunoglobulin [molecule] (five linked subunits), largely confined to plasma [that is] produced early in response to infecting organisms ...  4, record 1, English, - immunoglobulin%20M

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

Les IgM sont des immunoglobulines sécrétées lors du premier contact de l'organisme avec un antigène. Leur affinité pour l'antigène est plus faible que celle des IgG.  4, record 1, French, - immunoglobuline%20M

Record number: 1, Textual support number: 2 CONT

La principale caractéristique structurale des IgM réside dans l'existence de 2 formes moléculaires distinctes : 1) une forme monomère [...] 2) une forme pentamère [...]  5, record 1, French, - immunoglobuline%20M

Record number: 1, Textual support number: 3 CONT

La présence d'anticorps IgM [dirigés] contre le virus de l'hépatite A (anti-VHA), qui peut durer trois mois, permet de diagnostiquer une infection aiguë.  6, record 1, French, - immunoglobuline%20M

Record number: 1, Textual support number: 1 OBS

IgM: Ce terme figure dans l'article «immunoglobuline» du Larousse médical.  7, record 1, French, - immunoglobuline%20M

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Clase de anticuerpos producidos por el cuerpo como respuesta inicial a un antígeno.  1, record 1, Spanish, - inmunoglobulina%20M

Record number: 1, Textual support number: 1 OBS

Si la IgM se produce en respuesta a una vacuna, una vacuna de refuerzo producirá un "cambio" de IgM sobre todo a [la] inmunoglobulina G.  1, record 1, Spanish, - inmunoglobulina%20M

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

[An] immunoassay in which an enzyme is used as a marker to indicate the presence of specific antigens, [or] antibodies ...  4, record 2, English, - enzyme%20immunoassay

Record number: 2, Textual support number: 1 CONT

Several enzyme immunoassays(EIA) have been developed commercially to detect IgG [immunoglobulin G] or IgM [immunoglobulin M] to specific T. [Treponema] pallidum antigens and are useful in HIV co-infected patients.  5, record 2, English, - enzyme%20immunoassay

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Épreuve fondée sur la spécificité de la réaction antigène-anticorps et dans laquelle une enzyme est utilisée à titre de marqueur pour déterminer la présence ou la quantité d'antigènes ou d'anticorps spécifiques.  5, record 2, French, - %C3%A9preuve%20immunoenzymatique

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

An immunofixation electrophoresis yielded a dense, dark-staining band when patient's serum reacted with IgM [immunoglobulin M] antiserum. A band with the same electrophoretic mobility and similar density was seen when patient's serum reacted with kappa antiserum.  2, record 3, English, - kappa%20antiserum

Record 3,  Textual support,  French

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 OBS

There are five classes of immunoglobulins :(i) immunoglobulin G(IgG),(ii) immunoglobulin M(IgM),(iii) immunoglobulin A(IgA),(iv) immunoglobulin E(IgE), and(v) immunoglobulin D(IgD).  3, record 4, English, - immunoglobulin

Record number: 4, Textual support number: 2 OBS

For some authors, the term "immunoglobulin" is synonymous with the term "antibody." However, while all antibodies are immunoglobulins, not all immunoglobulins are antibodies.  4, record 4, English, - immunoglobulin

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

Les Ig comportent deux paires de chaînes polypeptidiques, une paire de chaînes légères et une paire de chaînes lourdes, reliées entre elles par des ponts disulfures.  3, record 4, French, - immunoglobuline

Record number: 4, Textual support number: 1 OBS

Les immunoglobulines sont divisées en cinq types : IgG, IgA, IgD, IgM et IgE; cette division est basée surtout sur la composante protéique la plus importante de l'immunoglobuline.  4, record 4, French, - immunoglobuline

Record number: 4, Textual support number: 2 OBS

Certains auteurs considèrent le terme «immunoglobuline» comme synonyme du terme «anticorps». Toutefois, tous les anticorps sont des immunoglobulines, mais les immunoglobulines ne sont pas toutes des anticorps.  5, record 4, French, - immunoglobuline

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

A mitogen acting mainly on B cells derived from the plant Phytolacca americana.  2, record 5, English, - pokeweed%20mitogen

Record number: 5, Textual support number: 1 CONT

Pokeweed mitogen stimulates both T and B cells, and can induce IgM synthesis by B cells.  3, record 5, English, - pokeweed%20mitogen

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Produit obtenu par le traitement de la phytolaque, qui a la propriété de provoquer la mitose des lymphocytes T et B.  1, record 5, French, - mitog%C3%A8ne%20de%20la%20phytolaque

Record number: 5, Textual support number: 1 CONT

Test de transformation blastique en présence de pokeweed mitogène (mitogène du phytolaque)  3, record 5, French, - mitog%C3%A8ne%20de%20la%20phytolaque

Record number: 5, Textual support number: 2 CONT

Certains mitogènes sont spécifiques des cellules T (phytohémagglutinine, concavaline A), d'autres, des cellules B (endotoxines), d'autres, enfin, stimulent à la fois les cellules B et T (pokeweed).  2, record 5, French, - mitog%C3%A8ne%20de%20la%20phytolaque

Record number: 5, Textual support number: 1 OBS

mitogène de la phytolaque : Terme et définition recommandés par l'OLF.  4, record 5, French, - mitog%C3%A8ne%20de%20la%20phytolaque

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  French

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

The first antibodies produced in a humoral immune response are IgM, but activated B cells subsequently undergo isotype switching or class switching to secrete antibodies of different isotypes : IgG [inmunoglobulin G], IgA, and IgE. Isotype switching does not affect antibody specificity significantly, but alters the effector functions that an antibody can engage. Isotype switching occurs by a site-specific recombination involving the deletion of the intervening DNA.  7, record 7, English, - isotype%20switching

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 DEF

Processus par lequel une cellule B peut associer de nouveaux gènes de chaînes lourdes d'immunoglobulines à son gène V recombiné pour produire un anticorps de même spécificité mais de classe différente.  3, record 7, French, - commutation%20isotypique

Record number: 7, Textual support number: 1 OBS

Ce processus est aussi retrouvé dans la commutation isotypique générale que l'on observe au cours de la maturation d'une réponse immunitaire.  3, record 7, French, - commutation%20isotypique

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 DEF

Proceso durante el cual una célula plasmática deja de producir anticuerpos de una clase y comienza a producirlos de otro distinta.  2, record 7, Spanish, - cambio%20de%20clase

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

The Bartels PRIMA SystemTM Cytomegalovirus IgM Enzyme Immunoassay is a rapid, qualitative method for the detection of IgM Antibody to cytomegalovirus in human serum. Patient serum is diluted with specimen diluent that contains an absorbent to remove IgG. The absorbent prevents IgG/rheumatoid factor complexes from forming and prevents interfering competition from IgG during the test procedure. The treated serum is incubated with purified CMV antigens bound to EIA plate wells. If antibodies to CMV are present, they bind to the antigen and do not rinse off. Subsequently, when enzyme labeled anti-human IgM is added to the reaction site, it binds to the immobilized antibodies. After washing and the addition of a chromogenic substrate and stop solution, specimens containing antibodies to CMV produce a color endpoint reaction which is measured and compared to negative and positive controls, and may be measured spectrophotometrically.  1, record 8, English, - chromogenic%20substrate

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

Dans ce cas, les dNTP (2-désoxyribonucléotides triphosphates peuvent être marqués par la biotine [...] Les produits d'amplification sont ensuite détectés directement par l'avidine ou la streptavidine couplée à la phosphatase alcaline ou à la peroxydase et le substrat chromogène correspondant.  1, record 8, French, - substrat%20chromog%C3%A8ne

Record 8,  Textual support,  Spanish

Record number: 8, Textual support number: 1 DEF

Compuesto o sustancia que contiene un grupo que produce color.  1, record 8, Spanish, - sustrato%20cromog%C3%A9nico

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 OBS

Term(s) taken from a Canadian laboratory-equipment company’s catalogue.  1, record 9, English, - EBV%20IgM%20heterophile%20antibody

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 OBS

Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire.  1, record 9, French, - anticorps%20h%C3%A9t%C3%A9rophile%20EBV%20IgM

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  French

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 OBS

Term(s) taken from a Canadian laboratory-equipment company’s catalogue.  1, record 11, English, - anti%2Dhuman%20IgM%20conjugate

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 OBS

Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire.  1, record 11, French, - conjugu%C3%A9%20d%27IgM%20anti%2Dhumaine

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 OBS

Term(s) taken from a Canadian laboratory-equipment company’s catalogue.  1, record 12, English, - anti%2Dhuman%20IgM

Record 12,  Textual support,  French

Record number: 12, Textual support number: 1 OBS

Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire.  1, record 12, French, - IgM%20anti%2Dhumaine

Record 12,  Textual support,  Spanish

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 DEF

A primary immunodeficiency disorder characterized by recurrent staphylococcal abscesses of skin, lungs, joints, and other sites, pruritic dermatitis, very serum IgE levels, normal levels of IgG, IgA, and IgM, blood and sputum eosinophilia, low anamnestic antibody responses to booster immunization, and poor antibody and cell-mediated responses to neoantigens.  1, record 13, English, - hyperimmunoglobulinemia%20E%20syndrome

Record number: 13, Textual support number: 1 CONT

hyperimmunoglobulinemia E: extremely high levels of IgE in the serum, associated with cutaneous anergy and deficient antibody response, as occurs in Job’s syndrome.  1, record 13, English, - hyperimmunoglobulinemia%20E%20syndrome

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 DEF

Syndrome d'immunodéficience caractérisé par des infections staphylococciques à répétition, en particulier cutanées, et des taux nettement élevés d'IgE. L'infection staphylococciques peut atteindre la peau, les poumons, les articulations et d'autres localisations.  1, record 13, French, - hypergammaglobulin%C3%A9mie%20IgE

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 CONT

Macroglobulinemia is the result of an uncontrolled proliferation of lymphocytes and plasma cells in which a large IgM M-protein is produced. The cause is unknown...  1, record 14, English, - Waldenstr%C3%B6m%26rsquo%3Bs%20macroglobulinemia

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Hémopathie lymphoïde B caractérisée par la présence d'une immunoglobuline M monoclonale (macroglobuline) à un taux supérieur à 5g/litre de sang associée à une infiltration lymphoplasmocytaire de la moelle osseuse et éventuellement d'autres organes.  1, record 14, French, - macroglobulin%C3%A9mie%20de%20Waldenstr%C3%B6m

Record 14,  Textual support,  Spanish

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 CONT

Coinfection [means] infection with more than one virus, bacterium, or other micro-organism at a given time. For example, an HIV-infected individual may be coinfected with hepatitis C virus (HCV) or tuberculosis (TB).  3, record 15, English, - coinfected

Record number: 15, Textual support number: 2 CONT

Several enzyme immunoassays(EIA) have been developed commercially to detect IgG [immunoglobulin G] or IgM [immunoglobulin M] to specific T. [Treponema] pallidum antigens and are useful in HIV co-infected patients.  2, record 15, English, - coinfected

Record 15,  Textual support,  French

Record number: 15, Textual support number: 1 CONT

Lorsqu'une personne a le VIH et une autre infection grave comme l'hépatite C, on dit qu'elle est co-infectée.  3, record 15, French, - co%2Dinfect%C3%A9

Record number: 15, Textual support number: 2 CONT

Il existe sur le marché plusieurs essais immuno-enzymatiques (EIA) servant à déceler les IgG [immunoglobulines G] ou les IgM [immunoglobulines M] dirigées contre des antigènes spécifiques de T. [Treponema] pallidum; [ceux-ci] sont utiles chez les patients co-infectés par le VIH.  4, record 15, French, - co%2Dinfect%C3%A9

Record 15,  Textual support,  Spanish

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 DEF

Antibody, usually IgM but occasionally IgG, that reacts less efficiently with antigen at 37 ° C than at lower temperatures.  1, record 16, English, - cold%20antibody

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 DEF

Anticorps dont la mise en évidence in vitro n'est franche qu'à basse température.  2, record 16, French, - anticorps%20froid

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 DEF

An antigen which does not require T lymphocyte participation to elicit an immune response in B lymphocytes. Animals lacking a thymus can respond to these antigens.  3, record 17, English, - thymus%2Dindependent%20antigen

Record number: 17, Textual support number: 2 DEF

An antigen that can trigger B cells to produce antibodies without the participation of T cells; most are polymers with a simple repeating pattern and are B cell mitogens; only IgM is produced and few memory cells are formed.  4, record 17, English, - thymus%2Dindependent%20antigen

Record number: 17, Textual support number: 1 CONT

T-independent antigens can directly stimulate B cells....  2, record 17, English, - thymus%2Dindependent%20antigen

Record 17,  Textual support,  French

Record number: 17, Textual support number: 1 DEF

Antigène vis-à-vis duquel la production des anticorps (essentiellement IgM) ne nécessite pas la présence des cellules T. La production de ces anticorps n'est cependant pas strictement thymo-indépendante car elle peut être soumise à l'action régulatrice de cellules T suppressives et amplificatrices.  1, record 17, French, - antig%C3%A8ne%20thymo%2Dind%C3%A9pendant

Record number: 17, Textual support number: 1 CONT

Antigènes thymo-indépendants: Type 1 (T.I.-1) : lipopolysaccharides (LPS), flagelline polymérisée, polyvinylpyrrolidone; Type 2 (T.I.-2) : polysaccharides solubles (par ex. polysaccharides SIII polymères synthétiques de D-acides aminés. (J.-F. Bach, P. Lesavre, Op. cit. p. 43.  3, record 17, French, - antig%C3%A8ne%20thymo%2Dind%C3%A9pendant

Record 17,  Textual support,  Spanish

Record 18,  Textual support,  English

Record number: 18, Textual support number: 1 DEF

Antibody that binds to erythrocytes or bacteria but does not produce agglutination.  1, record 18, English, - incomplete%20antibody

Record number: 18, Textual support number: 1 CONT

The nonagglutinating antibody is detectable with the antiglobulin(Coombs) test. For example, IgG anti-Rh antibodies do not agglutinate erythrocytes in physiologic saline whereas IgM antibodies do(the large IgM molecule can cross-link the erythrocytes at a wider separation so that there is less electrostatic repulsion due to the zeta potential).  1, record 18, English, - incomplete%20antibody

Record 18,  Textual support,  French

Record number: 18, Textual support number: 1 CONT

Un anticorps est dit «agglutinant» (les hématies) quand il entraîne l'hémagglutination en milieu salin (CINa 0,15 mol/l). Dans le cas contraire, on parle d'anticorps «non agglutinant».  1, record 18, French, - anticorps%20non%20agglutinant

Record number: 18, Textual support number: 2 CONT

En raison du faible nombre de site antigénique Rhésus [...], le nombre de molécules d'IgG anti-Rhésus fixées sur chaque hématie est insuffisant pour agglutiner les globules rouges : ces anticorps sont improprement appelés «incomplets» par opposition aux IgM anti-Rhésus qui sont agglutinants (anticorps complets).  2, record 18, French, - anticorps%20non%20agglutinant

Record number: 18, Textual support number: 1 OBS

anticorps incomplet (impropre). Source : J.-F. Bach, P. Lesavre, Op, Cit., p. 50.  2, record 18, French, - anticorps%20non%20agglutinant

Record 18,  Textual support,  Spanish

Record 19,  Textual support,  English

Record number: 19, Textual support number: 1 CONT

Selective IgA deficiency is the most common immuno-deficiency disorder, with a prevalence in the normal population of about 1 : 600. The IgA level is less than 5 mg %, while the level of other immunoglobulins(IgG, IgM) is normal. Most persons with selective IgA deficiency are asymptomatic. However, a variety of disorders are associated with this particular immunodeficiency : respiratory infections, autoimmune diseases; allergy....  1, record 19, English, - selective%20IgA%20deficiency

Record 19,  Textual support,  French

Record number: 19, Textual support number: 1 CONT

Le déficit en IgA est fréquent, touchant environ un individu sur 700 dans la population générale. Très souvent asymptomatique et de découverte fortuite, le déficit en IgA peut cependant être responsable d'infections ORL, bronchiques ou digestives. [...] Des manifestations allergiques sont parfois observées [...] On note également une fréquence anormale de manifestations auto-immunes [...]  1, record 19, French, - d%C3%A9ficit%20en%20IgA

Record 19,  Textual support,  Spanish

Record 20,  Textual support,  English

Record number: 20, Textual support number: 1 CONT

EAC rosette assay. An assay for human B lymphocytes using complement receptors, a B cell marker. Peripheral blood cell are mixed with ox red blood cells, IgM antierythrocyte antibody, and complement deficient in C5(to prevent red cell lysis). The antibody-and-complement-coated erythrocytes(EAC) form rosettes with B cells, which are counted using a hemocytometer.  1, record 20, English, - EAC%20rosette

Record 20,  Textual support,  French

Record number: 20, Textual support number: 1 CONT

De nombreuses cellules présentent sur leur membrane des récepteurs pour certains facteurs du complément, notamment le C3b, le C4b et peut-être le C1q. Ces récepteurs peuvent être objectivés par la formation de rosettes EAC avec des hématies recouvertes d'anticorps IgM anti-érythrocytaires et de complément à concentration non hémolytique. Ces récepteurs sont retrouvés sur la majorité des lymphocytes B, mais aussi sur les monocytes et les polynucléaires [...]  1, record 20, French, - rosette%20EAC

Record number: 20, Textual support number: 1 OBS

EAC = érythrocyte-anticorps-complément.  2, record 20, French, - rosette%20EAC

Record 20,  Textual support,  Spanish

Record 21,  Textual support,  English

Record number: 21, Textual support number: 1 CONT

EA Rosettes. Cells which have Fc receptors for IgM or IgG can be isolated by mixing with red cells sensitized with antibody(EA) of the appropriate class. The antibody crosslinks the red cell to the Fc receptor and the rosettes are then isolated.  1, record 21, English, - EA%20rosette

Record 21,  Textual support,  French

Record number: 21, Textual support number: 1 CONT

Ces récepteurs sont mis en évidence par fixation d'IgG agrégées préalablement rendues fluorescentes, ou mieux par formation de rosettes EA («érythrocytes-anticorps») avec des érythrocytes sensibilisés par des anticorps anti-érythrocytaires, à des concentrations non agglutinantes.  1, record 21, French, - rosette%20EA

Record number: 21, Textual support number: 1 OBS

EA = érythrocytes recouverts d'anticorps.  2, record 21, French, - rosette%20EA

Record 21,  Textual support,  Spanish

Record 22,  Textual support,  English

Record number: 22, Textual support number: 1 DEF

An immunogiobolin, usually IgM or IgG, that is defined by its reactivity with the Fc portion of IgG. It is commonly present in the serum of patients with chematoid arthritis.  1, record 22, English, - rheumatoid%20factor

Record 22,  Textual support,  French

Record number: 22, Textual support number: 1 DEF

Auto-anticorps, de classe IgM ou IgG reconnaissant des épitopes localisés au niveau de la portion Fc des IgG. Ils sont retrouvés chez les patients atteints de maladies inflammatoires touchant les articulations.  1, record 22, French, - facteur%20rhumato%C3%AFde

Record 22,  Textual support,  Spanish

Record 23,  Textual support,  English

Record number: 23, Textual support number: 1 DEF

A monomorphic polypeptide present in, and required for the polymerization of polymeric IgA and IgM.  2, record 23, English, - J%20Chain

Record 23,  Textual support,  French

Record number: 23, Textual support number: 1 DEF

Pièce de jonction polypeptidique qui, dans les IgA et les IgM, réunit les sous-unités.  1, record 23, French, - cha%C3%AEne%20J

Record 23,  Textual support,  Spanish

Record 24,  Textual support,  English

Record number: 24, Textual support number: 1 CONT

Waldenström’s macroglobulinemia is included in the B-cell lymphoproliferative syndromes that have a low degree of malignancy.  1, record 24, English, - Waldenstr%C3%B6m%26rsquo%3Bs%20macroglobulinemia

Record number: 24, Textual support number: 1 OBS

The disease results from a malignant proliferation of lymphoplasmacellular elements. As in multiple myeloma, a paraproteinemia is found which is always type IgM.  1, record 24, English, - Waldenstr%C3%B6m%26rsquo%3Bs%20macroglobulinemia

Record 24,  Textual support,  French

Record number: 24, Textual support number: 1 CONT

Syndromes lymphoprolifératifs [...] La macroglobulinémie (ou maladie de Waldenström) est caractérisée par l'association d'une prolifération lymphoïde généralement polymorphe et d'un pic d'IgM monoclonale sérique responsable d'une hyperviscosité sanguine. Les hémorragies sont fréquentes.  1, record 24, French, - maladie%20de%20Waldenstr%C3%B6m

Record 24,  Textual support,  Spanish

Record number: 24, Textual support number: 1 DEF

Extraño tipo de trastorno linoproliferativo crónico que afecta a los linfocitos B y que presenta un crecimiento lento. En cierto modo, evolución como el mieloma, en el sentido de que se origina en una cavidad de la médula ósea y causa malformaciones óseas.  1, record 24, Spanish, - macroglobulinemia%20de%20Waldenstrom

Record number: 24, Textual support number: 1 CONT

La macroglobulinemia de Waldenstrom presenta una incidencia más alta en varones mayores de 60 años.  1, record 24, Spanish, - macroglobulinemia%20de%20Waldenstrom

Record 25,  Textual support,  English

Record number: 25, Textual support number: 1 DEF

Increased viscosity of the blood occur(ring) with IgM and IgA myelomas because of the high levels of macroglobulins; causes increased resistance to blood, hypoxia, organ failure, retinal lesions, abnormalities in platelet function, coagulation defects and cardiac failure.  2, record 25, English, - serum%20hyperviscosity%20syndrome

Record 25,  Textual support,  French

Record number: 25, Textual support number: 1 OBS

Syndrome qui touche le sang des carnivores et qui peut se greffer à une autre affection, le myélome multiple.  2, record 25, French, - syndrome%20d%27hyperviscosit%C3%A9

Record 25,  Textual support,  Spanish

Record 26,  Textual support,  English

Record number: 26, Textual support number: 1 DEF

Monomeric IgM, IgD, and(on memory cell only) IgG that is attached to the cell membrane of B lymphocytes and which, in conjunction with T cell helper, triggers B cell activation on contact with antigen.  2, record 26, English, - B%20cell%20receptor

Record 26,  Textual support,  French

Record number: 26, Textual support number: 1 DEF

Immunoglobuline de type IgM, ancrée dans la membrane, et susceptible de lier l'antigène au niveau des parties variables NHS-terminales des chaînes lourdes (H) et légères (L), qui constituent le site de reconnaissance, support de la spécificité.  3, record 26, French, - r%C3%A9cepteur%20de%20l%27antig%C3%A8ne%20des%20lymphocytes%20B

Record 26,  Textual support,  Spanish

Record 27,  Textual support,  English

Record number: 27, Textual support number: 1 DEF

The presence of circulating antibodies, usually IgM, that can agglutinate red cells and do so most efficiently at temperatures below 37 °C. The cold agglutinins are directed against three types of polysaccharide red cell antigens :"I antigens, "expressed primarily on adult red cells, "i antigens, "expressed primarily on cells of fetuses and infants, and "Pr antigens, "which, unlike I and i antigens, are protease sensitive.  1, record 27, English, - cold%20agglutinin%20syndrome

Record 27,  Textual support,  French

Record number: 27, Textual support number: 1 CONT

(Les agglutinines froides) s'observent au cours de maladies infectieuses (infections à mycoplasma pneumoniae, mononucléose infectieuse, syphilis) ou peuvent révéler une maladie lymphoïde proche de la maladie de Waldenström dite maladie des agglutinines froides.  1, record 27, French, - maladie%20des%20agglutinines%20froides

Record 27,  Textual support,  Spanish

Record 28,  Textual support,  French

Record 28,  Textual support,  Spanish

Record 29,  Textual support,  French

Record 29,  Textual support,  Spanish

Record 30,  Textual support,  English

Record number: 30, Textual support number: 1 CONT

It appears... that T-ind antigens do not usually induce the maturation of a response involving class switching to IgG... Isotype switching from IgM to IgD is not a random event... Switching to IgA or IgE also occurs and cells producing these isotypes are concentrated in the appropriate mucosal areas... although there is universal agreement that T cells are important in controlling this phenomenon, the signals which control the switch are less well understood.  1, record 30, English, - switching

Record 30,  Textual support,  French

Record number: 30, Textual support number: 1 CONT

Commutation de classe (...) Un réarrangement génique supplémentaire est nécessaire à l'expression des autres classes d'immunoglobulines (autres que IgM et IdD). Cette commutation s'effectue dans des régions de structure particulière (S pour "switch") situées en amont de chaque gène de partie constante de chaîne lourde, à l'exception du gène oméga.  1, record 30, French, - commutation

Record 30,  Textual support,  Spanish

Record 31,  Textual support,  English

Record number: 31, Textual support number: 1 CONT

The lupus band test demonstrates the deposition of complement and immunoglobulin in the skin at the demoepidermal junction, shown here as a continuous band of IgM by direct immunofluorescence... Non-lesional, light-exposed skin should be used for this test.  1, record 31, English, - lupus%20band

Record 31,  Textual support,  French

Record number: 31, Textual support number: 1 CONT

Détection des bandes lupiques par immunofluorescence directe (pour le diagnostic du lupus érythémateux). Cet examen révèle un dépôt de complément et immunoglobulines à la jonction dermo-épidermique, représenté par une bande continue d'IgM. [...] Ce test doit être pratiqué sur un échantillon de peau extra-lésionnelle et exposé à la lumière.  1, record 31, French, - bande%20lupique

Record 31,  Textual support,  Spanish

Record 32,  Textual support,  English

Record number: 32, Textual support number: 1 DEF

An autoantibody that is active only at temperature below 37 ° C.  1, record 32, English, - cold%20autoantibody

Record number: 32, Textual support number: 1 CONT

Autoimmune haemolytic anemias.(...) Cold-reactive autoantibodies are often present in higher titres than the warm-reactive autoantibodies. The antibodies are primarily IgM and fix complement strongly. In most cases they are specific for the Ii blood group system.  1, record 32, English, - cold%20autoantibody

Record 32,  Textual support,  French

Record number: 32, Textual support number: 1 CONT

La majorité des autoanticorps froids de classe IgM reconnaissent l'antigène public I. (...) Les autoanticorps anti-I de classe IgM ne se fixent sur les hématies qu'à basse température (4 ° C) et non à la température du corps. Cette particularité n'est pas liée à une modification de l'autoanticorps IgM par la température mais aux propriétés particulières de la membrane érythrocytaire au froid comme le démontre la réactivité identique de l'anticorps à 0 ° C et à 37 ° C avec l'antigène I purifié.  1, record 32, French, - autoanticorps%20froid

Record number: 32, Textual support number: 2 CONT

Anémie hémolytique à auto-anticorps "froids" (...)  2, record 32, French, - autoanticorps%20froid

Record 32,  Textual support,  Spanish

Record 33,  Textual support,  English

Record number: 33, Textual support number: 1 DEF

Antibody to the Rh group of antigens found on human erythrocytes. Anti Rh antibodies may be synthesized either by a Rh+ mother with an Rh-fetus or an Rh+ patient who receives a transfusion of Rh-blood. Agglutinating anti-Rh antibodies are of IgM class. IgG anti-Rh antibodies can cross the placenta and cause hemolytic disease of the newborn.  1, record 33, English, - anti%2DRh%20antibody

Record 33,  Textual support,  French

Record number: 33, Textual support number: 1 CONT

Si une unité de sang D-positif est transfusée à un sujet Rhésus-négatif, des anticorps anti-D sont produits dans 60 à 80 p. cent des cas, alors que des anticorps anti-c et anti E n'apparaissent que dans 2 p. cent des cas de transfusions incompatibles. [...] Il n'existe pas d'anticorps naturels anti-Rhésus. Les anticorps anti-Rhésus apparaissent après une grossesse ou une transfusion incompatible; ils ont presque toujours de classe IgG. [...] ces anticorps sont improprement appelés "incomplets" par opposition aux IgM anti-Rhésus qui sont agglutinantes (anticorps complets).  1, record 33, French, - anticorps%20anti%2DRh%C3%A9sus

Record 33,  Textual support,  Spanish

Record 34,  Textual support,  English

Record number: 34, Textual support number: 1 DEF

Antibody that reacts with red cells carrying the A antigen, causing agglutination. Agglutinating anti-A antibodies are usually of the IgM class. Anti-A antibodies are found in the sera of subjects of blood group O and B.  1, record 34, English, - anti%2DA%20antibody

Record 34,  Textual support,  French

Record number: 34, Textual support number: 1 CONT

Système ABO. Landsteiner conclut : 1. à l'existence de deux antigènes ou substances de groupes sanguins différents : A et B [...]; 2. à la présence d'alloanticorps anti-A et anti-B chez les sujets qui n'ont pas l'antigène correspondant. [...] Tout sujet possède dans son sérum des agglutinines anti-A ou anti-B quand l'antigène correspondant est absent. [...] ce sont des anticorps naturels. [...] Par opposition, il existe de façon irrégulière chez certains sujets des anticorps anti-A ou anti-B immuns apparus à la suite d'une immunisation.  1, record 34, French, - alloanticorps%20anti%2DA

Record 34,  Textual support,  Spanish

Record 35,  Textual support,  English

Record number: 35, Textual support number: 1 DEF

Antibody that reacts with red cells carrying the B antigen, causing agglutination. Agglutinating anti-B antibodies are usually of the IgM class. Anti-B antibodies are found in the sera of subjects of blood group O and A.  1, record 35, English, - anti%2DB%20antibody

Record 35,  Textual support,  French

Record number: 35, Textual support number: 1 CONT

Système ABO. Landsteiner conclut : 1) à l'existence de deux antigènes ou substances de groupes sanguins différents : A et B (...); 2) à la présence d'alloanticorps anti-A et anti-B chez les sujets qui n'ont pas l'antigène correspondant. (...) Tout sujet possède dans son sérum des agglutinines anti-A ou anti-B quand l'antigène correspondant est absent. (...) ce sont des anticorps naturels. (...) Par opposition, il existe de façon irrégulière chez certains sujets des anticorps anti-A ou anti-B immuns apparus à la suite d'une immunisation.  1, record 35, French, - alloanticorps%20anti%2DB

Record 35,  Textual support,  Spanish

Record 36,  Textual support,  English

Record number: 36, Textual support number: 1 CONT

The company was also in the news last April when it reported developing a diagnostic assay for Alzheimer’s disease based on cerebrospinal fluid (CSF).  1, record 36, English, - diagnostic%20assay

Record number: 36, Textual support number: 2 CONT

Comparison of hepatitis B core antigens derived from human liver or synthesized in Escherichia coli and evaluation of their use in diagnostic assays for anti-HBc IgM.  2, record 36, English, - diagnostic%20assay

Record number: 36, Textual support number: 3 CONT

Diagnostic assays of the resistance of Aedes aegypti to organophosphate insecticides.  2, record 36, English, - diagnostic%20assay

Record number: 36, Textual support number: 1 OBS

Second context and example extracted from PASCAL data base.  2, record 36, English, - diagnostic%20assay

Record 36,  Textual support,  French

Record number: 36, Textual support number: 1 CONT

Comparaison des antigènes HBc dérivés de foie humain ou synthétisés dans Escherichia coli et évaluation de leur utilisation dans les méthodes diagnostiques pour l'IgM anti-HBc.  1, record 36, French, - m%C3%A9thode%20diagnostique

Record number: 36, Textual support number: 2 CONT

Doses diagnostiques de la résistance d'Aedes aegypti aux insecticides organophosphorés.  1, record 36, French, - m%C3%A9thode%20diagnostique

Record number: 36, Textual support number: 1 OBS

Contexte et exemple tirés de la base de données PASCAL.  1, record 36, French, - m%C3%A9thode%20diagnostique

Record 36,  Textual support,  Spanish

Record 37,  Textual support,  English

Record number: 37, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 37, English, - measle%20specific%20IgM

Record 37,  Textual support,  French

Record number: 37, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 37, French, - IgM%20rougeoleuse%20sp%C3%A9cifique

Record 37,  Textual support,  Spanish

Record 38,  Textual support,  English

Record number: 38, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 38, English, - rubella%20specific%20IgM

Record 38,  Textual support,  French

Record number: 38, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 38, French, - IgM%20rub%C3%A9oleuse%20sp%C3%A9cifique

Record 38,  Textual support,  Spanish

Record 39,  Textual support,  English

Record number: 39, Textual support number: 1 DEF

The heavy chain component of the immunoglobulin IgM.  1, record 39, English, - mu%20chain

Record 39,  Textual support,  French

Record number: 39, Textual support number: 1 DEF

Région constante de la chaîne lourde de l'immunoglobuline IgM.  2, record 39, French, - cha%C3%AEne%20mu

Record 39,  Textual support,  Spanish

Record 40,  Textual support,  English

Record number: 40, Textual support number: 1 CONT

By careful screening and mutation, a human-murine hybridoma suitable as a fusion partner for immortalizing an antibody-secreting B cell has been generated. The trioma fusion products of this immortalizing partner are stable producers of human monoclonal antibodies. A trioma which produces monoclonal human anti-varicella zoster is disclosed. A human anti-A IgM is also produced using this general method by the trioma S-H22 and by an alternate hybrid  1, record 40, English, - fusion%20partner

Record 40,  Textual support,  French

Record 40,  Textual support,  Spanish

Record 41,  Textual support,  English

Record number: 41, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 41, English, - rubella%20IgM%20antibody%20testing

Record 41,  Textual support,  French

Record number: 41, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 41, French, - d%C3%A9pistage%20des%20anticorps%20IgM%20antirub%C3%A9oliques

Record 41,  Textual support,  Spanish

Record 42,  Textual support,  English

Record number: 42, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 42, English, - IgM%20antibody%20response

Record 42,  Textual support,  French

Record number: 42, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 42, French, - %C3%A9laboration%20d%27anticorps%20IgM

Record 42,  Textual support,  Spanish

Record 43,  Textual support,  English

Record number: 43, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 43, English, - rubella%20IgM%20antibody

Record 43,  Textual support,  French

Record number: 43, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 43, French, - anticorps%20IgM%20antirub%C3%A9olique

Record 43,  Textual support,  Spanish

Record 44,  Textual support,  English

Record number: 44, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 44, English, - rubella%20IgM%20antibody%20positivity

Record 44,  Textual support,  French

Record number: 44, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 44, French, - positivit%C3%A9%20%C3%A0%20l%27%C3%A9gard%20de%20l%27anticorps%20IgM%20antirub%C3%A9olique

Record 44,  Textual support,  Spanish

Record 45,  Textual support,  English

Record number: 45, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 45, English, - rubella%20IgM%20antibody%20test

Record 45,  Textual support,  French

Record number: 45, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 45, French, - analyse%20de%20d%C3%A9tection%20de%20l%27anticorps%20IgM%20antirub%C3%A9olique

Record 45,  Textual support,  Spanish

Record 46,  Textual support,  English

Record number: 46, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 46, English, - rubella%20IgM

Record 46,  Textual support,  French

Record number: 46, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 46, French, - IgM%20rub%C3%A9oleuse

Record 46,  Textual support,  Spanish

Record 47,  Textual support,  English

Record number: 47, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 47, English, - measles%20IgM

Record 47,  Textual support,  French

Record number: 47, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 47, French, - IgM%20rougeoleuse

Record 47,  Textual support,  Spanish

Record 48,  Textual support,  English

Record number: 48, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 48, English, - specific%20IgM

Record 48,  Textual support,  French

Record number: 48, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 48, French, - IgM%20sp%C3%A9cifique

Record 48,  Textual support,  Spanish

Record 49,  Textual support,  English

Record number: 49, Textual support number: 1 OBS

Serum hepatitis A specific immunoglobulin M.  2, record 49, English, - serum%20hepatitis%20A%20specific%20IGM

Record number: 49, Textual support number: 2 OBS

Canada Diseases Weekly Report.  2, record 49, English, - serum%20hepatitis%20A%20specific%20IGM

Record 49,  Textual support,  French

Record number: 49, Textual support number: 1 OBS

Immunoglobuline M spécifique contre l'hépatite A dans le sérum des malades.  2, record 49, French, - IGM%20sp%C3%A9cifique%20contre%20l%27h%C3%A9patite%20A%20dans%20le%20s%C3%A9rum%20des%20malades

Record number: 49, Textual support number: 2 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 49, French, - IGM%20sp%C3%A9cifique%20contre%20l%27h%C3%A9patite%20A%20dans%20le%20s%C3%A9rum%20des%20malades

Record 49,  Textual support,  Spanish

Record 50,  Textual support,  English

Record number: 50, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 50, English, - IgM%20quantitation

Record 50,  Textual support,  French

Record number: 50, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 50, French, - dosage%20des%20IgM

Record 50,  Textual support,  Spanish

Record 51,  Textual support,  English

Record number: 51, Textual support number: 1 DEF

A method used to detect and enumerate antibody producing cells. Cells obtained from, e. g. the spleen of an animal that has been immunized against sheep erythrocytes, are mixed into molten Agarose containing sheep erythrocytes. The agarose is poured into a Petri dish, allowed to set and then incubated at 37 ° C. Later, complement is poured into the dish, and any cells that have secreted antibody are revealed by the appearance of a zone of haemolysis round each of them. The agarose layer can be dried and stained so that the cells may be identified. The technique described reveals IgM secreting cells forming direct plaques. By the addition of an anti-IgG serum before the complement, indirect plaques due to IgG secreting cells can be revealed. Cells producing antibodies to antigens other than erythrocytes can be detected by coating the rythrocytes with the antigen as in passive haemolysis.  1, record 51, English, - balmolytic%20plaque%20test

Record 51,  Textual support,  French

Record number: 51, Textual support number: 1 CONT

La méthode de numération par la technique des plages de lyse est utilisée dans certains laboratoires [...] pour le titrage de suspensions de cultures pures.  2, record 51, French, - technique%20des%20plages%20de%20lyse

Record 51,  Textual support,  Spanish

Record 52,  Textual support,  English

Record number: 52, Textual support number: 1 OBS

Canada Diseases Weekly Report.  2, record 52, English, - hepatitis%20A%20specific%20IGM

Record 52,  Textual support,  French

Record number: 52, Textual support number: 1 OBS

Rapport hebdomadaire des maladies au Canada.  2, record 52, French, - IGM%20sp%C3%A9cifique%20contre%20l%27h%C3%A9patite%20A

Record 52,  Textual support,  Spanish