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IMMUNE MEDIATED [13 records]

Record 1 2023-04-18

English

Subject field(s)
  • Human Diseases - Various
  • Immunology
  • Muscles and Tendons
CONT

IMNM can present much like polymyositis and causes muscle cell death (necrosis) that leads to weakness of the skeletal muscles on both sides of the body (symmetrical), commonly those closest to the body’s core (proximal), such as the hips, thighs, upper arms, shoulders, and neck. ... IMNM may look the same as necrotizing myopathies, but they have other features that prove they are autoimmune.

Key term(s)
  • immune mediated necrotizing myopathy
  • necrotizing auto-immune myopathy

French

Domaine(s)
  • Maladies humaines diverses
  • Immunologie
  • Muscles et tendons
Key term(s)
  • myopathie nécrosante autoimmune
  • myopathie nécrosante à médiation autoimmune

Spanish

Save record 1

Record 2 2011-08-17

English

Subject field(s)
  • Nervous System
CONT

Acute disseminated encephalomyelitis is an uncommon acute inflammatory disease of the CNS which occurs following viral infections or vaccination. ADEM is thought to be immune mediated. Brain and spinal cord involvement is usually widespread but may at times be limited to discrete areas such as the optic nerves or a single spinal cord level. Various names have been used to describe this syndrome but the term ADEM is appropriately descriptive.

French

Domaine(s)
  • Système nerveux
DEF

Démyélisation aiguë du système nerveux central pouvant être liée à un désordre immunologique, une maladie allergique, une maladie infectieuse, une prise de médicaments ou à une vaccination.

Key term(s)
  • encéphalo-myélite aiguë disséminée

Spanish

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Record 3 2010-06-04

English

Subject field(s)
  • Immunology
CONT

T cells are the regulators of the immune system. With the exception of cytotoxic T cells, many of the regulatory effects of T cells are exerted indirectly through other lymphocytes or nonlymphoid cells such as macrophages. In many instances T-cell function appears to be mediated by limphokines. Immunoregulatory lymphokines fall into two classes :...

French

Domaine(s)
  • Immunologie
CONT

Aspects immuno-régulateurs de la fonction placentaire : La grossesse peut être assimilée à la transplantation réussie d'une «greffe semi-allogénique». Les mécanismes immunitaires qui permettent l'implantation, puis le développement de l'embryon dans l'utérus, sont multiples mais intéressent principalement le placenta.

Spanish

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Record 4 2005-04-11

English

Subject field(s)
  • Symptoms (Medicine)
  • The Skin
CONT

Erythema multiforme is an immunologic reaction in the skin and mucous membranes often mediated by circulating immune complexes that evolve in response to a number of antigenic stimulae(infections, drugs, connective tissue disease). As the name implies, the skin reaction is characterized by a variety of lesions, namely, erythematous plaques, blisters, and target or bull' s-eye lesions. The mucous membranes of the mouth and eye may also be involved, and this is referred to as Stevens-Johnson syndrome.

French

Domaine(s)
  • Symptômes (Médecine)
  • Appareil cutané
DEF

Forme grave d'érythème polymorphe caractérisée par des lésions cutanées maculo-vésiculeuses ou bulleuses, avec atteinte simultanée des muqueuses (conjonctivite, stomatite, urétrite) et symptômes généraux (fièvre, anorexie).

Spanish

Campo(s) temático(s)
  • Síntomas (Medicina)
  • Piel
DEF

Forma de eritema multiforme que puede ser muy severo [...] y que se caracteriza por conjuntivitis que puede terminar en ceguera y por ulceraciones en los genitales y el ano.

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Record 5 2003-10-17

English

Subject field(s)
  • Cytology
CONT

The peripheral expression of CMI [cell-mediated immunity] usually represents a cooperation between immune T lymphocytes and macrophages, mediated by such LK [lymphokines] as chemotactic factor or macrophage activating factor.

OBS

chemotaxis: Directional migration of cells in response to chemical substances.

French

Domaine(s)
  • Cytologie
DEF

Relatif au chimiotactisme.

CONT

Les lymphokines manifestent un pouvoir chimiotactique puissant à l'égard des cellules sanguines, activent les macrophages et présentent de multiples propriétés [...]

OBS

chimiotactisme : Orientation des déplacements de cellules mobiles par des substances présentes dissymétriquement dans le milieu où les cellules se trouvent. [...] Ce sont des substances chimiques qui dans tous les cas sont responsables de la sensibilité.

Spanish

Campo(s) temático(s)
  • Citología
Save record 5

Record 6 2002-09-23

English

Subject field(s)
  • Immunology
CONT

Baudouin et al.(1992) assessed the possible ocular-protective effect of Ginkgo extract(EGb761) in rabbits. A model of periretinal proliferation was used to simulate retinal detachment by means of an immunologically-mediated inflammatory reaction, which in turn stimulated intra-ocular growth of vitreous stands. Their test followed observations of a possible immunologically-mediated activation of cell proliferation which they observed in specimens from human cases of periretinal proliferative disorders, which are the main cause of retinal-origin blindness. The researchers also found evidence of intravitreal macrophages and lymphocytes in the rabbits, indicating an immune-mdiated inflammatory response involved in the pathological state induced, and hypothesized in the etiology of proliferative retinal diseases in humans.

Key term(s)
  • immunologically mediated-inflammatory response
  • immunologically mediated inflammatory response
  • immune mediated inflammatory reaction
  • immune-mediated inflammatory reaction
  • immunologically mediated inflammatory reaction
  • immune mediated inflammatory response

French

Domaine(s)
  • Immunologie
CONT

Des souris immunisées dans le coussinet plantaire avec C.P. (Corynebacterium parvum) développent un mécanisme général capable de détruire les cellules tumorales de sensibilité générale aux antigènes de C.P. qui permet à une réaction inflammatoire à médiation immunologique de se concentrer au siège d'une injection de cellules tumorales ou dans le lit d'une tumeur établie, ce qui entraîne l'inhibition complète de la croissance des premières et la régression de la dernière.

OBS

réaction inflammatoire à médiation immunologique : terme tiré de la base de données PASCAL no : 76-0151428.

Spanish

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Record 7 2001-03-01

English

Subject field(s)
  • Immunology
OBS

This relatively new scientific discipline has shown that you are what you think! The relationship between cells of the immune system and cells of the nervous system is an intimate one mediated by cytokinins, chemical messengers secreted into the bloodstream(immune system) or the cerebro-spinal fluid(nervous system).

French

Domaine(s)
  • Immunologie
CONT

La recherche s'oriente depuis quelques années dans le domaine de la relation existante entre les trois systèmes : psychologique, neurologique et immunologique. Cette branche nouvelle de la science a pris pour nom «psychoneuroimmunologie».

Spanish

Save record 7

Record 8 1998-06-12

English

Subject field(s)
  • Pharmacology
Key term(s)
  • immune mediated

French

Domaine(s)
  • Pharmacologie

Spanish

Save record 8

Record 9 1996-11-06

English

Subject field(s)
  • Biochemistry
  • Genetics
CONT

Activation of macrophages by bacterial lipopolysaccharide(LPS) induces transcription of genes that encode for proinflammatory regulators of the immune response. Previous work has suggested that activation of the transcription factor activator protein 1(AP-1) is one LPS-induced event that mediates this response. Consistent with this notion, we found that LPS stimulated AP-1-mediated transcription of a transfected reporter gene in the murine macrophage cell line RAW 264. 7. As AP-1 activity is regulated in part by activation of the c-Jun N-terminal kinase(JNK), which phosphorylates and subsequently increases the transcriptional activity of c-Jun, we examined whether LPS treatment of macrophages resulted in activation of this kinase.

OBS

PNAS Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-sti. Proceedings of the National Academy of Sciences Volume 93, Number 07; Pages: 2774-2778 Immunology.

French

Domaine(s)
  • Biochimie
  • Génétique
OBS

JNK

Spanish

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Record 10 1996-03-29

English

Subject field(s)
  • Immunology
CONT

Sarcoidosis and eosinophilic gastro-enteritis are two other immune mediated diseases.

French

Domaine(s)
  • Immunologie
OBS

Terme construit sur le modèle de l'exemple suivant : L'origine de cette affection reste imprécise. Une origine allergique ou immunologique a été suspectée dans la description originelle [...] (Relevé dans EMEST, 1980, vol. 3 n° 9053A10, p. 10)

Spanish

Save record 10

Record 11 1993-03-23

English

Subject field(s)
  • Immunology
CONT

A regulatory group of T cells(T suppressors) are responsible for controlling the activity of T helper and B cells. Suppression is antigen-, idiotype-or non-specific. Antigen-specific suppression is often MHC restricted.... Suppression mediated by T cells is one mechanism by which the immune system could prevent the development of immune reactions to self molecules. Suppression is an active process and can be differentiated from tolerance by transferring the suppression with T cells.

French

Domaine(s)
  • Immunologie
CONT

Une suppression non spécifique de l'antigène peut être observée au cours de nombreuses réactions immunitaires à médiation humorale [...] ou cellulaire [...], toutes réactions faisant intervenir les cellules T.

Spanish

Save record 11

Record 12 1993-03-23

English

Subject field(s)
  • Immunology
CONT

A regulatory group of T cells(T suppressors) are responsible for controlling the activity of T helper and B cells. Suppression is antigen-, idiotype-or non-specific. Antigen-specific suppression is often MHC restricted.... Suppression mediated by T cells is one mechanism by which the immune system could prevent the development of immune reactions to self molecules. Suppression is an active process and can be differentiated from tolerance by transferring the suppression with T cells.

French

Domaine(s)
  • Immunologie
CONT

Suppression idiotypique. La réponse aux polysaccharides des streptocoques A fait intervenir des cellules Ts, qui sont apparemment analogues aux cellules Ts spécifiques d'allotypes [...]. L'injection d'anticorps anti-idiotypiques à des souris peut supprimer la synthèse des anticorps porteurs des spécificités idiotypiques correspondantes.

Spanish

Save record 12

Record 13 1993-03-22

English

Subject field(s)
  • Immunology
DEF

(Gell and Coombs classification) : Type 3 reactions are initiated by antigen-antibody complexes formed either at the site of tissue damage (Arthus reactions) or localizing from the circulation (soluble immune complex reactions).

French

Domaine(s)
  • Immunologie
DEF

Réaction d'immunité humorale. La combinaison antigène-anticorps susceptible de fixer le complément forme des immuncomplexes qui se déposent dans les parois vasculaires où ils provoquent une inflammation (phénomène d'Arthus). Les anticorps sont des IgG ou des IgM de type précipitant; les manifestations pathologiques apparaissent après quelques heures et la réaction est dite semi-retardée. En clinique, les alvéolites allergiques, la maladie sérique, certaines urticaires et glomérulonéphrites, le lupus érythémateux sont causés par réaction de type III.

Spanish

Save record 13

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