TERMIUM Plus®

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IMMUNOISOLATION [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2006-05-11

English

Subject field(s)
  • Immunology
CONT

[Immunoisolation, an] approach to eliminate the need for powerful anti-rejection drugs [, involves] the creation of protective barriers between the immune system and transplanted cells. The objective is to create a biocompatible "envelope" that can contain the transplanted islets, allow nutrients to flow in to maintain their health, allow glucose to enter the cells and, in response, to enable the secreted insulin to easily flow out and enter the blood stream.

Key term(s)
  • immuno-isolation

French

Domaine(s)
  • Immunologie
CONT

L'immunoisolement vient contrecarrer les attaques du système immunitaire en interposant une membrane semi-perméable entre le greffon et l'hôte [, ce qui] empêche l'entrée de substances de poids moléculaire plus élevé tels les anticorps [...] et les cellules du système immunitaire [...]

Key term(s)
  • immuno-isolation
  • immuno-isolement

Spanish

Save record 1

Record 2 2006-05-02

English

Subject field(s)
  • Immunology
CONT

Researchers are trying to develop methods of transplanting islet cells to reduce or eliminate the need for immunosuppression and the risk of rejection. Immunoisolation methods separate the islets from the immune system of the patient by coating cells or encapsulating them into microscopic containers. Immunoalteration tries to change the surface of islet cells so that the patient's immune system does not notice or attack them.

Key term(s)
  • immuno-alteration

French

Domaine(s)
  • Immunologie
DEF

Type d'immunoprotection qui consiste à réduire le caractère immunogène d'un greffon de sorte que, en théorie, le receveur n'ait pas à recevoir de traitement immunosuppresseur.

CONT

Tester sur ce modèle deux méthodes d'immunoaltération des îlots pancréatiques humains (suppression des cellules porteuses de molécules HLA [Human Leucocyte Antigen] de classe II (cellules non endocrines contaminant le greffon), masquage des molécules HLA de classe I, seules exprimées à la surface des îlots).

Key term(s)
  • immuno-altération

Spanish

Save record 2

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