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IMMUNOLOGIC RECEPTOR [2 records]

Record 1 2011-12-15

English

Subject field(s)
  • Immunology
DEF

The sum total of functionally diverse B and T cells in ones circulation at any given moment.

CONT

To allow recognition of many antigens, the immune system creates a large population of receptor molecules that differ in the primary sequence of their antigen-binding regions. This population is called the ‘immunologic repertoire’ and is formed by a process of diversification and selection quite different from the way other gene products are produced in our cells.

CONT

This lymphocyte "homing" process disperses the immunologic repertoire, directs lymphocyte subsets to the specialized microenvironments that control their differentiation and regulate their survival, and targets immune effector cells to sites of antigenic or microbial invasion.

French

Domaine(s)
  • Immunologie
CONT

Chaque lymphocyte porte des structures de reconnaissance ou sites récepteurs à l'antigène, tous identiques pour la même cellule, qui lui permettent d'identifier un motif chimique [...]. Le motif de l'antigène qui réagit avec ces sites récepteurs est dénommé déterminant antigénique. L'ensemble des sites de reconnaissance portés par les populations lymphocytaires définit le répertoire immunologique possédé par un organisme. On ne connaît pas exactement le nombre de possibilités de reconnaissance des lymphocytes ou le nombre de déterminants antigéniques.

Spanish

Save record 1

Record 2 2011-11-07

English

Subject field(s)
  • Immunology
DEF

A cell surface molecules on cell of the immune system that specifically binds surface molecules or messenger molecules and trigger changes in the behavior of cells.

CONT

Cells of the immune system expres s a wide variety of receptors, defined as immunoreceptors. These receptors are involved in antigen recognition, B and T lymphocytes express clonally distributed receptors which recognize soluble antigen for the B cell receptor (BcR) or peptide associated to major histocompatibility complex (MHC) molecules for the T cell receptor (TcR).

OBS

Although these receptors were first identified in the immune system, many have important functions elsewhere.

French

Domaine(s)
  • Immunologie
DEF

Récepteur spécifique exprimé par les cellules immunocompétentes.

CONT

Signalisation et transport cellulaire des immunorécepteurs. Des récepteurs spécifiques exprimés par les cellules immunocompétentes reconnaissent les antigènes: l'immunoglobuline membranaire exprimée par les lymphocytes B (BcR) les reconnaît sous forme soluble; le récepteur de l'antigène des lymphocytes T (TcR) reconnaît le complexe peptide antigénique-CMH exprimé à la surface des cellules présentatrices.

Spanish

Campo(s) temático(s)
  • Inmunología
Save record 2

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