TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Anthrax toxin proteins engineered to require activation by tumor-associated proteases show high specificity and potency in suppression of solid tumor growth through actions on tumor endothelial cells. The toxin strongly inhibits proliferation of tumor endothelial cells. Importantly, an immunosuppressive regimen(pentostatin plus cyclophosphamide) not only prevents induction of toxin-neutralizing antibodies, allowing multiple courses of toxin treatment, but also has strong synergy with the toxin on solid tumors.  1, record 1, English, - toxin%20therapy

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Emploi de toxines pour traiter certaines affections.  2, record 1, French, - toxinoth%C3%A9rapie

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

A mycosis caused by a fungus of low virulence that can establish an infection only as a consequence of factors such as the presence of debilitating disease or the administration of immunosuppressive and other therapeutic agents or radiation therapy.  1, record 2, English, - opportunistic%20mycosis

Record number: 2, Textual support number: 1 OBS

Most of the causal fungi are normally saprophytic in soil and decaying vegetation.  1, record 2, English, - opportunistic%20mycosis

Record number: 2, Textual support number: 2 OBS

B48.7: code used in the International Statistical Classification of Diseases and Related Health Problems.  2, record 2, English, - opportunistic%20mycosis

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Mycose causée par un champignon de faible virulence qui ne peut donner un état infectieux qu'en raison de la présence de certains facteurs tels que l'existence d'une maladie débilitante ou l'administration d'agents thérapeutiques immunosuppresseurs ou autres, ou de radiothérapie.  1, record 2, French, - mycose%20opportuniste

Record number: 2, Textual support number: 1 OBS

La plupart des champignons responsables sont des saprophytes habituels du sol et de végétaux en décomposition.  1, record 2, French, - mycose%20opportuniste

Record number: 2, Textual support number: 2 OBS

B48.7 : code de la Classification statistique internationale des maladies et des problèmes de santé connexes.  2, record 2, French, - mycose%20opportuniste

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

Any of a group of corticosteroids(as cortisol) that are involved especially in carbohydrate, protein, and fat metabolism, that are anti-inflammatory and immunosuppressive, and that are used widely in medicine(as to alleviate the symptoms of rheumatoid arthritis)...  2, record 3, English, - glucocorticoid

Record 3,  Textual support,  French

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

Antithymocyte globulin(ATG) is a concentrated anti-human T-lymphocyte immunoglobulin preparation derived from rabbits after immunization with a T-lymphoblast cell line. ATG is an immunosuppressive product for the prevention and treatment of acute rejection following organ transplantation. ATG reduces the host immune response against tissue transplants or organ allografts.  4, record 4, English, - antithymocyte%20globulin

Record number: 4, Textual support number: 2 CONT

Immunosuppressive therapy with antithymocyte globulin(ATG) plus cyclosporine is an effective alternative to stem-cell transplantation and improves blood counts and survival. Although horse ATG is the standard therapy, rabbit ATG is more potent in depleting peripheral-blood lymphocytes and is preferred in other clinical circumstances.  5, record 4, English, - antithymocyte%20globulin

Record 4,  Textual support,  French

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

Some of the AMPs [antimicrobial peptides] may be useful for humans. Clinical mycoses are on the increase with the increased use of immunosuppressants in transplants and also in immunosuppressive diseases. Antimicrobial peptides or drugs based on their mode of action may have pharmacological value in the future against human fungal pathogens.  2, record 5, English, - antimicrobial%20peptide

Record number: 5, Textual support number: 1 OBS

Antimicrobial peptide defenses: amino acid chains that generally disrupt the membranes of a target cell, causing the breakdown of the cell.  3, record 5, English, - antimicrobial%20peptide

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 CONT

Recherche de molécules à activité biologique: les peptides antimicrobiens. Depuis la découverte par le Professeur Hans Boman en 1980 du premier peptide antimicrobien, plus de cinq cents autres molécules ont été caractérisées. Ces peptides, mis en évidence dans tous les phyla, présentent un large spectre d'activité contre les bactéries, les champignons filamenteux et les levures. De nombreux travaux montrent qu'ils jouent un rôle clé dans les mécanismes immunitaires innés puisqu'ils participent efficacement, et cela chez tous les métazoaires, à la lutte contre les microorganismes que ce soit au niveau cellulaire (destruction des bactéries phagocytées), au niveau humoral ou encore au niveau des épithélia et des muqueuses.  2, record 5, French, - peptide%20antimicrobien

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 OBS

Proteínas de origen natural que tienen propiedades antibióticas [...]  1, record 5, Spanish, - p%C3%A9ptido%20antimicrobiano

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

A therapy designed to suppress the immune response.  2, record 6, English, - immunosuppressive%20therapy

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

La seule thérapie immuno-suppressive a consisté à administrer, par voie intraveineuse à des souris ayant subi une allogreffe de rein, deux doses d'anticorps (30 µg de chacune), le jour même de l'intervention et le lendemain.  1, record 6, French, - th%C3%A9rapie%20immuno%2Dsuppressive

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

A derivative of b-mercaptopurine, which is used as an immunosuppressive drug.  1, record 7, English, - azathioprine

Record number: 7, Textual support number: 1 OBS

Chemical formula: C₉H₇N₇O₂S  2, record 7, English, - azathioprine

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

L'azathioprine est indiquée comme traitement d'appoint pour la prévention du rejet d'homogreffe rénale.  2, record 7, French, - azathioprine

Record number: 7, Textual support number: 2 CONT

L'azathioprine est un immunodépresseur à action cytotoxique qui agit principalement sur les lymphocytes T.  3, record 7, French, - azathioprine

Record number: 7, Textual support number: 1 OBS

Formule chimique : C₉H₇N₇O₂S.  4, record 7, French, - azathioprine

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 DEF

Agente inmunosupresor utilizado sobre todo para prevenir el rechazo de órganos en pacientes transplantados.  2, record 7, Spanish, - azatioprina

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 DEF

An antibiotic produced by Steptomyces chrysomallus that inhibits the transcription of DNA to RNA by binding to DNA and that also has immunosuppressive activity.  3, record 8, English, - dactinomycin

Record number: 8, Textual support number: 1 CONT

Because actinomycin D inhibits RNA elongation in intact cells, as well as in cell extracts, it has become a very useful diagnostic tool for [the] identification of cell processes that depend upon RNA synthesis.  4, record 8, English, - dactinomycin

Record number: 8, Textual support number: 1 OBS

dactinomycin: International nonproprietary name (INN) of the World Health Organization (WHO).  5, record 8, English, - dactinomycin

Record number: 8, Textual support number: 2 OBS

Chemical formula: C₆₂H₈₆N₁₂O₁₆  6, record 8, English, - dactinomycin

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 DEF

Antibiotique antinéoplastique agissant par fixation sur la guanine du DNA, inhibant ainsi l'action de la DNA polymérase, administré par voie veineuse.  3, record 8, French, - dactinomycine

Record number: 8, Textual support number: 1 OBS

[La] forte toxicité [de la dactinomycine] pour le tissu hématopoïétique et l'épithélium digestif fait réserver son utilisation au traitement du néphroblastome, du choriocarcinome et de certains sarcomes.  3, record 8, French, - dactinomycine

Record number: 8, Textual support number: 2 OBS

dactinomycine : Dénomination commune internationale (DCI) de l'Organisation mondiale de la santé (OMS).  4, record 8, French, - dactinomycine

Record number: 8, Textual support number: 3 OBS

Formule chimique : C₆₂H₈₆N₁₂O₁₆  5, record 8, French, - dactinomycine

Record 8,  Textual support,  Spanish

Record number: 8, Textual support number: 1 DEF

Fármaco antibiótico antineoplásico.  3, record 8, Spanish, - actinomicina%20D

Record number: 8, Textual support number: 1 OBS

[...] utilizado en el tratamiento de tumores germinales, tumor del Wilms, sarcoma de Ewing, rabdomiosarcoma embrionario, enfermedad trofoblástica gestacional y sarcoma de Kaposi.  3, record 8, Spanish, - actinomicina%20D

Record number: 8, Textual support number: 2 OBS

Fórmula química: C₆₂H₈₆N₁₂O₁₆  4, record 8, Spanish, - actinomicina%20D

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 DEF

Cytostatic agent with antiviral and immunosuppressive properties.  5, record 9, English, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dmethoxyphenyl%5Dmethanesulfonamide

Record number: 9, Textual support number: 1 OBS

N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide: The capital letter "N" must be italicized; form recommended by the IUPAC (International Union of Pure and Applied Chemistry).  1, record 9, English, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dmethoxyphenyl%5Dmethanesulfonamide

Record number: 9, Textual support number: 2 OBS

N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide: The capital letter "N" must be italicized.  6, record 9, English, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dmethoxyphenyl%5Dmethanesulfonamide

Record number: 9, Textual support number: 3 OBS

Chemical formula: C₂₁H₁₉N₃O₃S  7, record 9, English, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dmethoxyphenyl%5Dmethanesulfonamide

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 OBS

[...] puissant agent cytotoxique.  4, record 9, French, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dm%C3%A9thoxyph%C3%A9nyl%5Dm%C3%A9thanesulfonamide

Record number: 9, Textual support number: 2 OBS

N-[4-(acridin-9-ylamino)-3-méthoxyphényl]méthanesulfonamide : La lettre majuscule «N» s'écrit en italique; forme recommandée par l'UICPA (Union internationale de chimie pure et appliquée).  1, record 9, French, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dm%C3%A9thoxyph%C3%A9nyl%5Dm%C3%A9thanesulfonamide

Record number: 9, Textual support number: 3 OBS

N,-4-(9-acridinylamino)-3-méthoxyphényl-méthanesulfonamide : La lettre majuscule «N» s'écrit en italique.  5, record 9, French, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dm%C3%A9thoxyph%C3%A9nyl%5Dm%C3%A9thanesulfonamide

Record number: 9, Textual support number: 4 OBS

Formule chimique : C₂₁H₁₉N₃O₃S  5, record 9, French, - N%2D%5B4%2D%28acridin%2D9%2Dylamino%29%2D3%2Dm%C3%A9thoxyph%C3%A9nyl%5Dm%C3%A9thanesulfonamide

Record 9,  Textual support,  Spanish

Record number: 9, Textual support number: 1 OBS

Fórmula química: C₂₁H₁₉N₃O₃S  2, record 9, Spanish, - amsacrina

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 OBS

A fungal toxin produced by various species of Trichoderma, Gladiocladium fimbriatum, Aspergillus fumigatus, and Penicillium. It is used as an immunosuppressive agent.  2, record 10, English, - gliotoxin

Record number: 10, Textual support number: 2 OBS

Chemical formula: C₁₃H₁₄N₂O₄S₂  3, record 10, English, - gliotoxin

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 OBS

Formule chimique : C₁₃H₁₄N₂O₄S₂  2, record 10, French, - gliotoxine

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 DEF

Any drug ... used to suppress antibody production.  5, record 11, English, - immunosuppressive%20drug

Record number: 11, Textual support number: 1 CONT

The sixth lookback has a lower count [of CD4 lymphocytes] not because of HIV but because he has a disease being treated with immune suppressants.  3, record 11, English, - immunosuppressive%20drug

Record number: 11, Textual support number: 2 CONT

His studies involve collection of comprehension of drug safety and effectiveness. He is particularly interested in anti-immune drug and drug digoxin.  4, record 11, English, - immunosuppressive%20drug

Record number: 11, Textual support number: 1 OBS

anti-immune : tending to block or inhibit immunity.  6, record 11, English, - immunosuppressive%20drug

Record number: 11, Textual support number: 2 OBS

immunity : A state of increased resistance against the harmful effects of a noxious agent, as an infectious agent or toxin.  6, record 11, English, - immunosuppressive%20drug

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 DEF

[...] médicament [...] capable de diminuer, voire de supprimer les réactions immunitaires d'un organisme vis-à-vis d'un antigène.  1, record 11, French, - m%C3%A9dicament%20immunod%C3%A9presseur

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 DEF

A method of inducing a strong immunosuppressive effect in patients undergoing bone marrow transplants, treatment of certain lymphomas, or other therapies requiring immunosuppression.  2, record 12, English, - total%20lymphoid%20irradiation

Record 12,  Textual support,  French

Record number: 12, Textual support number: 1 CONT

L'irradiation lymphoïde totale (ILT) supprime pour longtemps la fonction des lymphocytes T auxiliaires.  1, record 12, French, - irradiation%20lympho%C3%AFde%20totale

Record 12,  Textual support,  Spanish

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 DEF

A protein to which immunosuppressive drugs bind.  2, record 13, English, - immunophilin

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 DEF

Protéine cytoplasmique, à laquelle se lient les drogues immunosuppressives, comme la cyclosporine A.  1, record 13, French, - immunophilline

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 DEF

Equine antiserum against human lymphocytes, a powerful nonspecific immunosuppressive agent that causes destruction of circulating lymphocytes.  1, record 14, English, - antilymphocyte%20serum

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Globuline obtenue en injectant au cheval des lymphocytes animaux ou humains, utilisés comme immunosuppresseur dans les greffes d'organes.  1, record 14, French, - s%C3%A9rum%20antilymphocytaire

Record 14,  Textual support,  Spanish

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 DEF

Any of a group of biologically active metabolites of Tolypocladium inflatum Gams and certain other fundi.  2, record 15, English, - cyclosporin

Record number: 15, Textual support number: 1 CONT

Immunosuppressants (azathioprine, cyclosporin).  3, record 15, English, - cyclosporin

Record number: 15, Textual support number: 1 OBS

The major forms are cyclosporin A and C, which are cyclic oligopeptides with immunosuppressive, antifungal, and antipyretic effects. As immunosuppressants, cyclosporins affect primarily the T cell lymphocytes.  2, record 15, English, - cyclosporin

Record 15,  Textual support,  French

Record number: 15, Textual support number: 1 DEF

Médicament immunosuppresseur utilisé contre le rejet des greffes, contre les maladies auto-immunes, et contre les agents du paludisme et de la schistosomiase. (D'après le Monde, 5 mars 1984, p. V).  3, record 15, French, - cyclosporine

Record number: 15, Textual support number: 1 OBS

Polypeptide produit par un champignon, Tolypocladium inflatum.  2, record 15, French, - cyclosporine

Record 15,  Textual support,  Spanish

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 DEF

immunosuppressive agent : A physical(e. g. X-irradiation), chemical(e. g. azathiopine), or biological agent(e. g. anti-lymphocyte serum), that inhibits the stimulation of an immune response by an antigen.  1, record 16, English, - immunosuppressive

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 CONT

Les thérapeutiques immunosuppressives administrées pour combattre les rejets de greffe pourraient donc être responsables de l'apparition de cancers cutanés après transplantation d'organes. Les cancers cutanés consécutifs aux greffes représentent donc un modèle d'étude approprié permettant d'élargir les recherches en immunologie et en pharmacologie.  1, record 16, French, - immunosuppressif

Record number: 16, Textual support number: 1 OBS

Le féminin de immunosuppressif est immunosuppressive.  3, record 16, French, - immunosuppressif

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 DEF

An immunosuppressive agent used to control rejection of organ transplantation and autoimmune diseases.  1, record 17, English, - cyclosporin%20A

Record 17,  Textual support,  French

Record number: 17, Textual support number: 1 DEF

Prototype d'une famille de drogues à activité immunosuppressive, qui préviennent l'activation des lymphocytes T en bloquant les voies de signalisation de la membrane au noyau.  1, record 17, French, - cyclosporine%20A

Record 17,  Textual support,  Spanish

Record 18,  Textual support,  English

Record number: 18, Textual support number: 1 CONT

Phagocytic dysfunction disorder may be extrinsic(e. g., suppression of the number of phagocytes by immunosuppressive agents, or dysfunction caused by corticosteroids) or intrinsic(related to enzymes deficiencies) ;they are marked by bacterial or, sometimes, fungal infections, which range from mild recurrent skin infection to fatal systemic infection.  1, record 18, English, - phagocytic%20dysfunction%20disorder

Record 18,  Textual support,  French

Record number: 18, Textual support number: 1 CONT

Déficit des cellules phagocytaires. Les cellules phagocytaires jouent un rôle prépondérant dans l'immunité non spécifique. Les déficits des principaux types de cellules phagocytaires (polynucléaires, monocytes et macrophages) peuvent être quantitatifs (neutropénies ou agranulocytoses) ou qualitatifs (granulomatose septique et maladie de Chediak-Higsashi).  1, record 18, French, - d%C3%A9ficit%20des%20cellules%20phagocytaires

Record 18,  Textual support,  Spanish

Record 19,  Textual support,  English

Record number: 19, Textual support number: 1 OBS

(Results) suggest that microsurgical tubal transplantation with an appropriate immunosuppressive regimen warrants further investigation as potential treatment for certain infertility problems in the human.(abstract)(Pregnancy after Tubo-ovarian Transplantation)(Obstet. Gynecol., 1987, 70(2), pp. 229-234)  1, record 19, English, - tubal%20transplantation

Record 19,  Textual support,  French

Record number: 19, Textual support number: 1 OBS

Huit transplantations tubaires vascularisées ont été réalisées dans le monde et confrontées lors du premier colloque international sur la transplantation tubaire (Grenoble, février 1980).  1, record 19, French, - transplantation%20tubaire

Record 19,  Textual support,  Spanish