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INHIBITING CHROMOSOMES [1 record]

Record 1 1979-03-27

English

Subject field(s)
  • Genetics
CONT

Based on the observation that somatic-cell hybrids between normal and malignant mouse cells are malignant only when there is a loss of mouse chromosomes, several investigators have suggested in recent years that normal cells must contain genes capable of suppressing the cells’ ability to induce tumors; the loss of the "inhibiting chromosomes" carrying these genes would therefore result in the expression of malignancy.

French

Domaine(s)
  • Génétique
DEF

Chromosome susceptible d'enrayer la capacité des cellules à produire des tumeurs.

CONT

C'est pourquoi la perte des "chromosomes inhibiteurs" portant ces gènes se traduirait par l'expression de la malignité.

OBS

inhibition: Blocage d'un processus physiologique par une intervention extérieure également d'origine physiologique (...)

Spanish

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