TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

An enzyme that catalyzes the conversion of adenosine to the nucleoside inosine through the removal of an amino group.  4, record 1, English, - adenosine%20deaminase

Record number: 1, Textual support number: 1 OBS

A deficiency of ADA can lead to severe combined immunodeficiency syndrome.  4, record 1, English, - adenosine%20deaminase

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Enzyme qui catalyse une réaction d'hydrolyse de la fonction amine de l'adénosine la transformant en inosine.  2, record 1, French, - d%C3%A9saminase%20de%20l%27ad%C3%A9nosine

Record number: 1, Textual support number: 1 OBS

Le déficit en adénosine-désaminase peut être responsable d'un déficit immunitaire combiné sévère constitutionnel.  2, record 1, French, - d%C3%A9saminase%20de%20l%27ad%C3%A9nosine

Record number: 1, Textual support number: 2 OBS

désaminase de l'adénosine : désignation publiée au Journal officiel de la République française le 4 février 2021.  4, record 1, French, - d%C3%A9saminase%20de%20l%27ad%C3%A9nosine

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Enzima que cataliza la conversión de adenosina a inosina.  1, record 1, Spanish, - adenosina%20desaminasa

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

The measurement of hypxanthine, xanthine, inosine and uridine in umbilical cord blood and fetal scalp blood samples as a measure of fetal hypoxia.  2, record 2, English, - fetal%20scalp%20sample

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 OBS

Les auteurs rapportent un cas où le diagnostic d'anémie fœtale grave par saignement d'un vasa previa, complication obstétricale rare, a été porté à temps grâce à l'hématocrite prélevé sur le cuir chevelu du fœtus.  2, record 2, French, - pr%C3%A9l%C3%A8vement%20de%20sang%20provenant%20du%20cuir%20chevelu%20du%20f%26oelig%3Btus

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

In yeast, inosine(I) is found at position 34 of 7 different isoacceptor tRNA species. Using as substrates in vitro T7-transcripts of 31 plasmids carrying each natural or synthetic tRNA gene harbouring an anticodon with A-34, we have characterised a yeast enzyme that catalyses the conversion of A-34 to I-34. The base conversion occurs by a hydrolytic deamination-type reaction. This newly characterised tRNA : A-34 deaminase was partially purified from yeast.  1, record 3, English, - isoacceptor%20tRNA

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Terme qui décrit les différents tRNA (RNAt) spécifiques d'un même aminoacide.  2, record 3, French, - ARNt%20isoaccepteur

Record number: 3, Textual support number: 1 CONT

Tenant compte de ces faits, nous avons recherché les éléments d'identité responsables de l'arginylation spécifique chez la levure, en étudiant in vitro, les propriétés d'arginylation de toute une série de transcrits dérivés de l'ARNt-Asp, considéré comme un isoaccepteur pour l'arginine. En parallèle des expériences similaires ont été réalisées avec des transcrits dérivés de l'ARNt-Arg.  1, record 3, French, - ARNt%20isoaccepteur

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 OBS

An explanation of how a specific transfer RNA(tRNA) molecule can translate different codons in a messenger RNA template : there is some looseness in the alignment that allows the third base of the anticodon to pair with a base other than its normal complementary base. Other than the normal complementary pairs of guanine(G), with cytosine(C) and adenine(A) with uracil(U), G pairs with U, U pairs with G, and I(inosine) pairs with A, U, or C, where the first base of these pairs is the third base of the anticodon.  2, record 4, English, - Wobble

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 OBS

[L'hypothèse] indique que pour la 3e base du codon, la règle d'appariement stricte des bases avec celle de l'anticodon n'est pas respectée.  1, record 4, French, - Wobble

Record 4,  Textual support,  Spanish

Record number: 4, Textual support number: 1 DEF

[Hipótesis que] explica cómo un ARNt [ácido ribonucleico transmisor] puede reconocer a más de un codón.  1, record 4, Spanish, - hip%C3%B3tesis%20del%20titubeo

Record number: 4, Textual support number: 1 OBS

Las dos primeras bases del codón y anticodón del ARNm [ácido ribonucleico mensajero] se aparean correctamente, pero la tercera base del anticodón tiene cierta flexibilidad que le permite aparearse bien con la base esperada o con una alternativa.  1, record 4, Spanish, - hip%C3%B3tesis%20del%20titubeo

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

A chemical compound which appears under the form of odourless, colourless or white crystals, of a white crystalline powder or of a syrupy liquid, is derived from the biosynthesis of purine bases, is freely soluble in water, slightly soluble in ethanol, and is used as a flavour enhancer.  5, record 5, English, - inosinic%20acid

Record number: 5, Textual support number: 1 OBS

Chemical formula: C₁₀H₁₃N₄O₈P  5, record 5, English, - inosinic%20acid

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Liquide sirupeux dérivé de la biosynthèse des bases puriques, miscible à l'eau, [que l'on utilise] comme exhausteur de goût.  4, record 5, French, - acide%20inosinique

Record number: 5, Textual support number: 1 OBS

Formule chimique : C₁₀H₁₃N₄O₈P  5, record 5, French, - acide%20inosinique

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 OBS

A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules.  2, record 6, English, - inosine

Record number: 6, Textual support number: 2 OBS

Chemical formula: C₁₀H₁₂N₄O₅  3, record 6, English, - inosine

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 OBS

Formule chimique : C₁₀H₁₂N₄O₅  2, record 6, French, - inosine

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

Chirality about the trigonal axis. The quenchers are 6-coordinate Co(III) complexes with the general stoichiometric formula Co(NH3) 4(ndp) or Co(NH3) 4(ntp), where ndp denotes a diphosphate nucleotide ligand and ntp denotes a triphosphate nucleotide ligand. In these complexes the nucleotide ligand is coordinated to Co(III) via bidentate chelation in which the donor moieties are oxygen atoms from adjacent phosphate groups(beta, alpha in ndp and gamma, beta in ntp nucleotides). The nucleotides used as ligands in Ln in this study are the following : adenosine diphosphate and triphosphate(adp and atp), guanosine diphosphate and triphosphate(gdp and gtp), inosine diphosphate and triphosphate(idp and itp), cytidine triphosphate(ctp), uridine triphosphate(utp), and deoxythymidine triphosphate(ttp). The Co(NH3) 4(nucleotide) complexes have dissymmetric structures both within and external to the Co(NH3) 4(phosphate) coordination unit, but under the conditions employed in this study, they exist as mixtures of diastereomers that are quasi-racemic with respect to chirality within the Co(NH3) 4(phosphate) coordination units.  1, record 7, English, - diphosphate%20nucleotide

Record 7,  Textual support,  French

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 DEF

An enzyme of the transferase class that catalyzes the reaction hypoxanthine(of guanine) + 5-phospho-alpha-Delta-ribose I-disphosphate=inosine 5’-monophosphate(or guanasine 5’-monoiphosphate) + pyrophosphate.  1, record 8, English, - hypoxanthine%20phosphoribosyltransf%C3%A9rase

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

Une modification directe du gène Hprt (hypoxanthine phosphoribosyltransférase), pour lequel il est possible de sélectionner les cellules possédant cette fonction (avec le milieu HAT : hypoxanthine-aminoptérine-thymidine) ou au contraire les cellules qui l'ont perdue (avec la 6-TG : 6-thioguanine) peut aussi être obtenue.  1, record 8, French, - hypoxanthine%20phosphoribosyltransf%C3%A9rase

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

("Unusual" means a base other than A, G, C, or U.) Many of the unusual bases differ from normal bases by the presence of one or more methyl(-CH₃) groups. Most, if not all, of the methyl groups are enzymatically added after the nucleotides are linked together by 3’-5’ phosphodiester linkages. Very probably, the other unusual bases also arise by the enzymatic modification of a preexisting polynucleotide. The function of the unusual bases is not yet clear. They are not limited to alanine tRNA but occur in varying proportions in all tRNA molecules. Our only hint of their role is the fact that several unusual bases cannot form conventional base pairs. Some of the unusual bases may thus have the function of disruption double-helical hairpin regions, thereby exposing free keto and amino groups which can then form secondary bonds. Depending upon the specific bases, the free groups may form secondary bonds to template RNA, to a ribosome, or to the enzyme needed to attach a specific amino acid to its specific tRNA molecule. [Examples of those rare nucleotides are :Inosine, 1-methylinosine, N²-dimethylguanosine, 1-methylguanosine, Ribothymidine, Dihydrouridine and Pseudouridine].  1, record 9, English, - unusual%20base

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 CONT

Les deux classes de bases trouvées dans tous les mononucléotides sont dérivées de corps aromatiques hétérocycliques appelés purine et pyrimidine. La purine dérive elle-même de la pyrimidine par la fusion d'un cycle pyrimidine et imidazole. Les trois bases pyrimidiques les plus communes sont : l'uracile, la thymine et la cytosine, désignées couramment par U, T et C respectivement. Les bases puriques intervenant le plus souvent comme composantes des mononucléotides sont l'adénine et la guanine, respectivement désignées par A et G. Il existe [aussi] de nombreuses bases rares, telles que la 5-méthylcytosine, ou la 5-hydroxyméthyl-cytosine, [l'ionosine, la pseudouridine, etc...] Le rôle de ces bases rares n'est pas clair pour l'instant. Elles (...) existent en proportions variables dans toutes les molécules de tARN. Seul indice connu sur leur rôle possible, ces bases rares ne peuvent pas s'apparier de la manière habituelle. Certaines de ces bases rares pourraient donc avoir pour fonction de provoquer l'ouverture de quelques régions en épingle à cheveux de la double hélice, exposant ainsi des groupements cétones et aminés libres susceptibles de former des liaisons secondaires. Selon la nature des bases exposées, ces groupements libres pourraient former des liaisons secondaires avec la matrice d'ARN, avec le ribosome ou avec l'enzyme qui attache l'acide aminé à son tARN spécifique.  1, record 9, French, - base%20rare

Record 9,  Textual support,  Spanish