TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

Model, explaining the great specificity of enzymes for their substrates, in which the enzyme has an active site complementary to the shape of the substrate. If the substrate has a different shape, it not bind.  2, record 1, English, - lock%2Dand%2Dkey%20relationship

Record number: 1, Textual support number: 1 CONT

One of the first important studies on the specificity of enzymes was carried out by Emil Fischer, who found that enzymes capable of hydrolyzing glycosides can distinguish between their stereoisomeric forms. In 1894 this observation led him to enunciate the principle that the substrate molecule fits the active site of the enzyme in a... lock-and-key relationship.... Nowadays, the modified concept of transition state stabilization is gaining favor. According to this idea, it is not that the substrate is distorted but rather that the transition state makes better contacts with the enzyme than the substrate does, so that the full binding energy is not realized until the transition state is reached. Nevertheless, we shall use the term strain to cover the general situation on enzyme-transition state complementary.  3, record 1, English, - lock%2Dand%2Dkey%20relationship

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Modèle de complémentarité structurale évoqué par E. Fischer qui implique une structure rigide de l'enzyme, s'adaptant rigoureusement à son substrat. Cependant, les variations d'entropie, relativement élevées, observées lors de la formation du complexe enzyme-substrat, ont conduit à admettre que ce processus est accompagné de changements de conformation des molécules.  2, record 1, French, - mod%C3%A8le%20clef%2Dserrure

Record number: 1, Textual support number: 1 CONT

Les enzymes montrent une grande spécificité à l'égard de leur substrat et souvent, elles n'accepteront pas de molécules apparentées dont la conformation est légèrement différente. Ceci peut s'expliquer en supposant que l'enzyme et le substrat ont une relation de clé à serrure. [...] L'enzyme possède un site actif complémentaire de la forme du substrat. Si la conformation du substrat est différente, il ne sera pas lié.  3, record 1, French, - mod%C3%A8le%20clef%2Dserrure

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

Examination of the aircraft engine at the accident site found that a steel blanking cap from the engine's fuel supply system was missing. That cap covered a test port on a threaded ’T-fitting’ that led to the engine fuel control unit. The test port allowed for the checking of un-metered fuel pressure from the engine driven fuel pump. The cap was normally fastened to the T-fitting and a torque applied to it to ensure that it remained securely fastened.  2, record 2, English, - blanking%20cap

Record number: 2, Textual support number: 1 PHR

Pressure refuel blanking cap.  3, record 2, English, - blanking%20cap

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Appareil, dispositif servant à obturer quelque chose.  2, record 2, French, - obturateur

Record number: 2, Textual support number: 1 OBS

obturer : Boucher (une ouverture, un trou) de manière relativement complète.  2, record 2, French, - obturateur

Record number: 2, Textual support number: 2 OBS

obturateur : terme uniformisé par le Comité d'uniformisation de la terminologie aéronautique (CUTA) - Maintenance.  3, record 2, French, - obturateur

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 OBS

LED: linguistic eligibility determination  2, record 3, English, - LED%20site

Record number: 3, Textual support number: 2 OBS

Terminology used by Citizenship and Immigration Canada.  2, record 3, English, - LED%20site

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 OBS

DACL : détermination de l'admissibilité à un cours de langue  2, record 3, French, - centre%20de%20DACL

Record number: 3, Textual support number: 2 OBS

Cours de langue pour les immigrants au Canada (CLIC)  2, record 3, French, - centre%20de%20DACL

Record number: 3, Textual support number: 3 OBS

Terminologie employée par Citoyenneté et Immigration Canada.  2, record 3, French, - centre%20de%20DACL

Record 3,  Textual support,  Spanish