TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

MYELODYSPLASIA [3 records]

Record 1 2003-11-21

English

Subject field(s)
  • National Bodies and Committees (Canadian)
  • Blood
OBS

Aplastic anemia is a rare but extremely serious disorder that results when the marrow fails to produce blood cells. Aplastic anemia may be either acquired or inherited. Myelodysplasia is similar to aplastic anemia in that production of blood cells is decreased; however, the blood cells which are produced in myelodysplasia may not function properly. Aplastic anemia patients who do not receive a bone marrow transplant may go on to develop myelodysplasia which, in turn, can progress to leukemia.

French

Domaine(s)
  • Organismes et comités nationaux canadiens
  • Sang
OBS

Appellations et abréviations confirmées par l'organisme.

Spanish

Save record 1

Record 2 1997-05-14

English

Subject field(s)
  • Biochemistry
  • Genetics
CONT

Marrow Colony Assay is designed to quantitate the frequency of progenitor cells(BFU-E and CFU-GM) in the marrow and to determine if BFU-E and CFU-GM mature appropriately under optimal conditions in culture. This assay may help discriminate pure red cell aplasia that results from an immunologic process(where BFU-E growth is normal in culture) from pure red cell aplasia secondary to myelodysplasia(where BFU-E growth is low or absent).

French

Domaine(s)
  • Biochimie
  • Génétique
CONT

A l'origine, ces facteurs de croissance ont été introduits en pratique clinique afin de corriger ou de limiter les cytopénies induites par les chimiothérapies. Il a cependant été rapidement constaté qu'ils étaient aussi capables d'augmenter la concentration des progéniteurs circulants de tous types, comme les [CFU-GM], les BFU-E (burst-forming unit erythrocytes), les [CFU-GEMM].,ou le LTC-IC.

OBS

Utilisé en thérapie cellulaire.

Spanish

Save record 2

Record 3 1991-10-21

English

Subject field(s)
  • Blood
DEF

Abnormal formation of blood cell precursors in bone marrow.

French

Domaine(s)
  • Sang
CONT

Une augmentation de la fréquence de leucémies aiguës myéloïdes après traitement pour maladie de Hodgkin est devenue évidente. Ces leucémies sont habituellement précédées d'une phase de myélodisplasie qui dure plusieurs mois.

Spanish

Save record 3

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