TERMIUM Plus^®

Record 1,  Textual support,  French

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

There are too few of at least two types of blood cells(red blood cells, platelets, or white blood cells) ;less than 5% of the cells in the bone marrow are blasts and less than 1% of the cells in the blood are blasts; if red blood cells are affected, they may have extra iron; refractory cytopenia may progress to acute myeloid leukemia(AML).  3, record 2, English, - refractory%20cytopenia%20with%20multilineage%20dysplasia

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Il y a trop peu d'au moins 2 types de cellules sanguines (globules rouges, globules blancs, plaquettes) dans le sang; si les globules rouges sont affectés, ils pourraient contenir trop de fer; moins de 1 % des cellules dans le sang et moins de 5 % des cellules dans la moelle osseuse sont des blastes; la CRDM peut évoluer en LAM [leucémie aiguë myéloblastique].  2, record 2, French, - cytop%C3%A9nie%20r%C3%A9fractaire%20avec%20dysplasie%20multilign%C3%A9e

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

Refractory anemia with excess blasts (RAEB) is an MDS [myelodysplastic syndrome] characterized by increased myeloblasts in the bone marrow and/or blood or the presence of Auer rods. The thresholds of what constitutes an increase in blasts differ in the blood and bone marrow.  3, record 3, English, - refractory%20anemia%20with%20excess%20blasts

Record number: 3, Textual support number: 2 CONT

There are too few red blood cells in the blood and the patient has anemia; five percent to 19% of the cells in the bone marrow are blasts; there also may be changes to the white blood cells and platelets; refractory anemia with excess blasts may progress to acute myeloid leukemia(AML).  4, record 3, English, - refractory%20anemia%20with%20excess%20blasts

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Il y a trop peu de globules rouges dans le sang et présence d'anémie; des changements peuvent avoir affecté les globules blancs et les plaquettes; le nombre de blastes dans le sang est normal (moins de 5 %); l'AREB est divisée en 2 catégories qui se basent sur le pourcentage de blastes dans la moelle osseuse : AREB-1 – de 5 à 9 % des cellules dans la moelle osseuse sont des blastes; AREB-2 – de 10 à 19 % des cellules dans la moelle osseuse sont des blastes. Environ 25 % des cas d'AREB-1 et 33 % des cas d'AREB-2 évoluent en LAM [leucémie aiguë myéloblastique].  2, record 3, French, - an%C3%A9mie%20r%C3%A9fractaire%20avec%20exc%C3%A8s%20de%20blastes

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

The occurrence of myeloid tissue in extramedullary sites; specifically, a syndrome characterized by splenomegaly, anemia, the presence of nucleated erythrocytes and immature granulocytes in the circulating blood, and extramedullary hematopoiesis in the liver and spleen.  2, record 4, English, - myeloid%20metaplasia

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Transformation de cellules épithéliales glandulaires, en cellules myoépithéliales.  1, record 4, French, - m%C3%A9taplasie%20my%C3%A9lo%C3%AFde

Record number: 4, Textual support number: 1 OBS

du foie et de la rate. Enviroguide Benzène, chap. 7.  1, record 4, French, - m%C3%A9taplasie%20my%C3%A9lo%C3%AFde

Record 4,  Textual support,  Spanish

Record number: 4, Textual support number: 1 DEF

Enfermedad hematológica rara, caracterizada por fibrosis (proliferación del tejido conectivo fibroso) de la médula ósea, esplenomegalia (bazo anormalmente grande) y anemia (disminución de los hematíes o glóbulos rojos circulantes) con hematíes en forma de lágrima.  1, record 4, Spanish, - metaplasia%20mieloide

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 CONT

The myeloproliferative disorders comprise a group of usually neoplastic diseases, which may be related histogenetically by a common multipotential stem cell, that includes among others acute and chronic granulocytic leukemias, acute and chronic myelomonocytic leukemias, polycythemia vera, myelofibrosis, myeloid metaplasia, essential thrombocytemia, and erythroleukemia. An interrelationship with the lymphoproliferative disorders is thought to exist.  1, record 5, English, - myeloproliferative%20disorder

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Hémopathie caractérisée par une prolifération des cellules de la série myéloïde se produisant électivement au niveau de la moelle osseuse.  1, record 5, French, - syndrome%20my%C3%A9loprolif%C3%A9ratif

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 DEF

Término que designa cuatro trastornos sanguíneos diferentes, de los que sólo la leucemia mieloide crónica es cancerosa. Los otros son policitemia vera, metaplasia mieloide agnogénica y trombocitemia esencial.  1, record 5, Spanish, - trastorno%20mieloproliferativo

Record number: 5, Textual support number: 1 CONT

Los hematólogos tratan los trastornos mieloproliferativos, de los que un número considerable acaban leucemia mieloide aguda.  1, record 5, Spanish, - trastorno%20mieloproliferativo

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

A form of acute myeloid leukemia(AML) involving the cells that give rise to the erythrocytes(the red blood cells).  4, record 6, English, - erythroleukemia

Record number: 6, Textual support number: 1 OBS

In this type of leukemia, the body produces large numbers of abnormal, immature red blood cells.  4, record 6, English, - erythroleukemia

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 DEF

Affection sanguine caractérisée par l'apparition dans le sang périphérique d'érythroblastes et de myéloblastes atypiques.  1, record 6, French, - %C3%A9rythroleuc%C3%A9mie

Record number: 6, Textual support number: 1 CONT

Les caractères cytologiques de l'érythroleucoblastose sont à la fois ceux d'une leucose aiguë et ceux d'une érythroblastose maligne.  1, record 6, French, - %C3%A9rythroleuc%C3%A9mie

Record 6,  Textual support,  Spanish

Record number: 6, Textual support number: 1 DEF

Extraño tipo de leucemia no linfocítica aguda que afecta tanto a los glóbulos rojos como a los blancos.  1, record 6, Spanish, - eritroleucemia

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

A bifunctional cytotoxic alkylating agent, 1, 4-butanediol dimethanesulfonate, an antineoplastic agent unrelated to the nitrogen mustards; used primarily for treatment of chronic granulocytic leukemia and also polycythemia vera and myeloid metaplasia; the major side effect is bone marrow depression.  4, record 7, English, - busulfan

Record number: 7, Textual support number: 1 OBS

Chemical formula: C₆H₁₄O₆S₂ or C₆H₁₄S₂O₆  5, record 7, English, - busulfan

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 DEF

Poudre cristalline, insoluble dans l'eau, peu soluble dans l'alcool utilisé entre autres dans le traitement de la leucémie myéloïde.  5, record 7, French, - busulfan

Record number: 7, Textual support number: 1 OBS

Formule chimique : C₆H₁₄S₂O₆ ou C₆H₁₄O₆S₂  6, record 7, French, - busulfan

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 DEF

Fármaco alquilante antineoplásico.  2, record 7, Spanish, - busulfano

Record number: 7, Textual support number: 1 OBS

[...] utilizado para el tratamiento de la leucemia mielógena crónica, y neoplasia de la médula ósea.  2, record 7, Spanish, - busulfano

Record number: 7, Textual support number: 2 OBS

Fórmula química: C₆H₁₄O₆S₂ o C₆H₁₄S₂O₆  3, record 7, Spanish, - busulfano

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 DEF

A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow.  3, record 8, English, - leukemia

Record number: 8, Textual support number: 1 CONT

leukemia... is classified according to degree of cell differentiation as acute or chronic(terms no longer referring to duration of disease), and according to predominant type of cell involved as myelogenous [myeloid] or lymphocytic [lymphoid].  3, record 8, English, - leukemia

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 DEF

Maladie maligne et évolutive affectant les organes hémapoïétiques, marquée par une prolifération et un développement anormaux des leucocytes et de leurs précurseurs dans le sang et la moelle osseuse.  2, record 8, French, - leuc%C3%A9mie

Record number: 8, Textual support number: 1 CONT

[...] la leucémie [...] peut être aiguë ou chronique, myéloïde ou lymphoïde (en fonction du type de prolifération cellulaire).  3, record 8, French, - leuc%C3%A9mie

Record 8,  Textual support,  Spanish

Record number: 8, Textual support number: 1 DEF

Enfermedad consistente en la producción excesiva de leucocitos por los órganos encargados de ello.  2, record 8, Spanish, - leucemia

Record number: 8, Textual support number: 1 OBS

Cáncer de las células precursoras de los glóbulos blancos.  3, record 8, Spanish, - leucemia

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 DEF

Any of several hematopoietic stem cells identified by their ability to give rise to monoclonal colonies in the spleen when transplanted into isogeneic, lethally irradiated mice, including pluripotent myeloid stem cells and the precursors of neutrophils and monocytes, eosinophils, erythrocytes and megakariocytes.  1, record 9, English, - colony%2Dforming%20unit

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 CONT

Les cellules souches CFU de chaque lignée se différencient ensuite vers les précurseurs identifiables sur un frottis de moelle par la cytolyse classique. Différents facteurs inducteurs et inhibiteurs régulent la production de cellules matures à partir de la cellule souche unipotente.  1, record 9, French, - cellule%20souche%20unipotente

Record 9,  Textual support,  Spanish

Record number: 9, Textual support number: 1 DEF

Célula viva y aislada que se encuentra en un sustrato y en condiciones ambientales adecuadas [...] produce una colonia en un lapso de tiempo breve.  1, record 9, Spanish, - unidad%20formadora%20de%20colonias

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 DEF

Chemical substance, produced by microorganisms, inhibiting or preventing the development of neoplasms.  2, record 10, English, - cytotoxic%20antibiotic

Record number: 10, Textual support number: 1 CONT

Gemtuzumab ozogamicin is targeted against CD33, a surface marker expressed by 90% of myeloid leukemic blasts but absent from stem cells, and is armed with calicheamicin, a potent cytotoxic antibiotic that inhibits DNA synthesis and induces apoptosis.  3, record 10, English, - cytotoxic%20antibiotic

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 CONT

La mithramycine, ou plicamycine, est un antibiotique cytotoxique, utilisé parfois comme agent antitumoral.  2, record 10, French, - antibiotique%20cytotoxique

Record number: 10, Textual support number: 2 CONT

La bléomycine est un antibiotique cytotoxique utilisé dans le traitement des lymphomes, des carcinomes épimerdoïdes et des tumeurs testiculaires.  3, record 10, French, - antibiotique%20cytotoxique

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 DEF

Pertaining to, derived from, or manifesting certain features of the bone marrow.  2, record 11, English, - myeloid

Record number: 11, Textual support number: 1 CONT

Chronic myeloid disorders.  1, record 11, English, - myeloid

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 DEF

Qui se rapporte à la moelle osseuse, qui lui ressemble ou qui en provient.  2, record 11, French, - my%C3%A9lo%C3%AFde

Record number: 11, Textual support number: 1 CONT

Cellules hématopoïétiques dérivant de la lignée myéloïde.  1, record 11, French, - my%C3%A9lo%C3%AFde

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record 12,  Textual support,  French

Record 12,  Textual support,  Spanish

Record number: 12, Textual support number: 1 DEF

Leucemia caracterizada por la proliferación incontrolada de los mielocitos y sus precursores en la médula espinal y otras localizaciones.  1, record 12, Spanish, - leucemia%20mieloide

Record number: 12, Textual support number: 1 CONT

El síndrome mielodisplásico y la leucemia mieloide son complicaciones tardías de la terapia mieloablativa con apoyo autólogo de médula ósea o de células madres de la sangre periférica.  1, record 12, Spanish, - leucemia%20mieloide

Record 13,  Textual support,  French

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 DEF

A cancer of blood cells, characterized by replacement of the bone marrow with malignant leukemic cells.  1, record 14, English, - chronic%20myeloid%20leukemia

Record number: 14, Textual support number: 1 OBS

Many of these leukemic cells can be found circulating in the blood and can cause enlargement of the spleen, liver and other organs.  1, record 14, English, - chronic%20myeloid%20leukemia

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Affection néoplasique, appartenant au groupe des syndromes myéloprolifératifs, se traduisant par une accumulation de cellules myéloides.  1, record 14, French, - leuc%C3%A9mie%20my%C3%A9lo%C3%AFde%20chronique

Record 14,  Textual support,  Spanish

Record number: 14, Textual support number: 1 DEF

Uno de los cuatro tipos más importantes de leucemia, caracterizado por un aumento de la producción de leucocitos que se acumulan en el torrente sanguíneo y en la médula ósea.  1, record 14, Spanish, - leucemia%20mieloide%20cr%C3%B3nica

Record number: 14, Textual support number: 1 CONT

La leucemia mieloide crónica se asocia a la anomalía cromosómica denominada cromosoma Filadelfia.  1, record 14, Spanish, - leucemia%20mieloide%20cr%C3%B3nica

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 CONT

The cost-effectiveness of idarubicin/cytosine arabinoside versus daunorubicin/ccytosine arabinoside in the treatment of adults with acute myeloid leukemia.  1, record 15, English, - idarubicin

Record 15,  Textual support,  French

Record 15,  Textual support,  Spanish

Record number: 15, Textual support number: 1 DEF

Fármaco antibiótico antineoplásico.  1, record 15, Spanish, - idarubicina

Record number: 15, Textual support number: 1 OBS

[...] utilizado en el tratamiento de la leucemia mielógena crónica, leucemia no linfocítica aguda y leucemia linfocítica aguda.  1, record 15, Spanish, - idarubicina

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 CONT

Multiparametric analysis including clinical, biochemical, morphological, immunological, and cytogenetic investigations were performed in 100 patients with primary acute myeloid leukemia(AML). Patients were treated according to the protocol of the German AML Cooperative Group. Patients over 60 years of age received a study protocol of our department(idarubicin plus cytarabin).  1, record 16, English, - cytarabin

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 OBS

La cytarabine est la seule molécule antitumorale d'origine marine actuellement commercialisée (sous le nom de Aracytine) dans le monde, isolée chez Thetya crypta (éponge) qui provient de la Mer des Caraïbes.  2, record 16, French, - cytarabine

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 CONT

Multiple genes encoding type I transmembrane molecules and belonging to the immunoglobulin superfamily have recently been localized to human chromosome 19q13. 4. These include a family of genes encoding killer cell inhibitory receptors(KIR) expressed on natural killer(NK) cells and subsets of T-lymphocytes, immunoglobulin-like transcripts(ILT-1,-2 and 3) expressed on myeloid cells and subsets of lymphoid cells, the gp49 family of receptors expressed on mast cells and NK cells and the gene encoding human myeloid immunoglobulin A Fc receptor(CD89).  3, record 17, English, - killer%20cell%20inhibitory%20receptor

Record 17,  Textual support,  French

Record number: 17, Textual support number: 1 CONT

[...] l'identification et la caractérisation des récepteurs de types inhibiteurs spécifiques des allèles du CMH de classe 1 (KIR, killer cell inhibitory receptor) ont permis de comprendre les mécanismes de reconnaissance spécifique et de lyse de cellules tumorales ayant perdu l'expression de certaines molécules de classe 1.  1, record 17, French, - r%C3%A9cepteur%20inhibiteur%20de%20la%20lyse%20NK

Record 17,  Textual support,  Spanish

Record 18,  Textual support,  English

Record number: 18, Textual support number: 1 CONT

Mutations of CBP has recently been discovered to be responsible for cases of heritable Rubinstein-Taybi syndrome, an autosomal-dominant disorder which causes mental retardation and a predisposition to several forms of cancers. Further, transposition of CBP, which fuses the histone acetyl transferase domain of CBP to MOZ gene has been found in acute myeloid leukemia. The above two observations suggest that p300 and CBP may be tumor suppressor genes.  1, record 18, English, - MOZ%20gene

Record 18,  Textual support,  French

Record number: 18, Textual support number: 1 CONT

Le clonage positionnel du point de cassure de translocation a été réalisé de façon à rechercher les gènes impliqués dans le déterminisme de la maladie. Cela a mis en évidence l'existence au niveau du point de cassure d'un gène chimérique provenant de la fusion du gène codant pour le co-activateur de transcription CBP (CREB binding protein) en 16p13.3 avec un gène nouvellement identifié, MOZ (monocytic leukaemia zinc finger protein) sur le chromosome 8p11.  1, record 18, French, - g%C3%A8ne%20MOZ

Record 18,  Textual support,  Spanish

Record 19,  Textual support,  French

Record 19,  Textual support,  Spanish

Record 20,  Textual support,  English

Record number: 20, Textual support number: 1 CONT

Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor-beta in patients with myelofibrosis with myeloid metaplasia.  3, record 20, English, - transforming%20growth%20factor%20beta

Record number: 20, Textual support number: 1 OBS

Tiré de: British Journal of Haematology, 1991, 77 (11), 80-86.  3, record 20, English, - transforming%20growth%20factor%20beta

Record 20,  Textual support,  French

Record number: 20, Textual support number: 1 CONT

Comme pour la régulation des chaînes A et B du PDGF, très peu de choses sont connues sur la régulation des sous-unités du récepteur. Le TGF-bêta (transforming growth factor beta) diminue l'expression des ARNm de la sous-unité alpha et augmente celle de la sous-unité Bêta sur des fibroblastes murins.  3, record 20, French, - facteur%20de%20croissance%20transformant%20b%C3%AAta

Record 20,  Textual support,  Spanish

Record 21,  Textual support,  French

Record 21,  Textual support,  Spanish

Record 22,  Textual support,  French

Record 22,  Textual support,  Spanish

Record 23,  Textual support,  English

Record number: 23, Textual support number: 1 DEF

A granulocytic precursor cell which grows in vitro culture in the presence of appropriate stimulators.  1, record 23, English, - colony%2Dforming%20unit%2Dculture

Record number: 23, Textual support number: 1 CONT

... colony forming cells giving rise to ... granulocytes (G-CFC) or ... macrophages (M-CFC) or ... both (GM-CFC) ... are collectively referred to as CFU-C....  3, record 23, English, - colony%2Dforming%20unit%2Dculture

Record number: 23, Textual support number: 2 CONT

... Hematopoietic stem cell(giving rise to) common myeloid progenitor, common lymphoid progenitor....  2, record 23, English, - colony%2Dforming%20unit%2Dculture

Record 23,  Textual support,  French

Record number: 23, Textual support number: 1 CONT

Trois catégories de cellules phagocytaires. [...] Leur origine est connue, dans la moelle osseuse, sous la forme des cellules souches hématopoïétiques (CFU-S) et des cellules souches myéloïdes (CFU-C), ces dernières donnant naissance en présence d'un médiateur, le CSF ("colony stimulating factor") à des colonies mixtes de macrophages et de polynucléaires.  1, record 23, French, - cellule%20souche%20my%C3%A9lo%C3%AFde

Record 23,  Textual support,  Spanish